1 NM-PP1
- CAS No.
- 221244-14-0
- Chemical Name:
- 1 NM-PP1
- Synonyms
- CS-920;1 NM-PP1;NM-PP1, 1-;Chebi:52309;PP1 ANALOG II;PP1 Analog II, 1NM-PP1;1NM-PP1(PP1 Analog II);MUTANT KINASES INHIBITOR II;PP1 Analog II, 1NM-PP1 - CAS 221244-14-0 - Calbiochem;4-AMINO-1-TERT-BUYTL-3-(1-NAPHTHYLMETHYL)PYRAZOLO[3,4-D]PYRIMIDINE
- CBNumber:
- CB9146400
- Molecular Formula:
- C20H21N5
- Molecular Weight:
- 331.41
- MDL Number:
- MFCD03425470
- MOL File:
- 221244-14-0.mol
- MSDS File:
- SDS
Melting point | 175-176°C |
---|---|
Boiling point | 545.7±45.0 °C(Predicted) |
Density | 1.25±0.1 g/cm3(Predicted) |
storage temp. | Keep in dark place,Sealed in dry,Store in freezer, under -20°C |
solubility | Chloroform (Slightly), Methanol (Slightly, Heated) |
pka | 4.50±0.30(Predicted) |
form | White solid |
color | White to Beige |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07,GHS03 |
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Signal word | Warning | |||||||||
Hazard statements | H315-H319-H272 | |||||||||
Precautionary statements | P501-P220-P210-P221-P264-P280-P302+P352-P370+P378-P337+P313-P305+P351+P338-P362+P364-P332+P313 | |||||||||
NFPA 704 |
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1 NM-PP1 price More Price(33)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | 529606 | InSolution PP1 Analog II, 1NM-PP1 - CAS 221244-14-0 - Calbiochem | 221244-14-0 | 1mg | $172 | 2024-03-01 | Buy |
Sigma-Aldrich | 529581 | PP1 Analog II, 1NM-PP1 - CAS 221244-14-0 - Calbiochem PP1 Analog II, CAS 221244-14-0, is a cell-permeable PP1 analog that acts as a potent, reversible, selective, ATP-competitive inhibitor of mutant over wild-type kinases. | 221244-14-0 | 1mg | $159 | 2024-03-01 | Buy |
Cayman Chemical | 13330 | 1-NM-PP1 ≥95% | 221244-14-0 | 1mg | $75 | 2024-03-01 | Buy |
Cayman Chemical | 13330 | 1-NM-PP1 ≥95% | 221244-14-0 | 5mg | $150 | 2024-03-01 | Buy |
Cayman Chemical | 13330 | 1-NM-PP1 ≥95% | 221244-14-0 | 10mg | $263 | 2024-03-01 | Buy |
1 NM-PP1 Chemical Properties,Uses,Production
Description
1-
Chemical Properties
White Cyrstalline Solid
Uses
A highly potent (IC50=4.3 nM) and uniquely specific tyrosine kinase inhibitor of a rationally engineered v-Src tyrosine kinase
Definition
ChEBI: 1-NM-PP1 is a pyrazolopyrimidine. It has a role as a tyrosine kinase inhibitor.
References
[1] bishop ac1, ubersax ja, petsch dt, matheos dp, gray ns, blethrow j, shimizu e, tsien jz, schultz pg, rose md, wood jl, morgan do, shokat km. a chemical switch for inhibitor-sensitive alleles of any protein kinase. nature. 2000 sep 21; 407 (6802): 395-401.
1 NM-PP1 Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32836 | 60 |
career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29888 | 58 |
Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10311 | 58 |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49392 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
Chemia Biotechnology(Shanghai) Co., Ltd | +8613816753574 | info@chemia-pharm.com | CHINA | 311 | 58 |
Finetech Industry Limited | +86-27-87465837 +8618971612321 | info@finetechnology-ind.com | China | 9640 | 58 |
Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10522 | 58 |
InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
Coresyn Pharmatech Co., Ltd. | +86-571-86626709 +86-18157142896 | cbc@coresyn.com | China | 9991 | 58 |