alpha-2-Chloroisodurene
- CAS No.
- 1585-16-6
- Chemical Name:
- alpha-2-Chloroisodurene
- Synonyms
- MESITYL ALCOHOL;MESITYLMETHANOL;AKOS BBS-00003968;AZ-CHLOROISODURENE;α2-Chloroisodurene;A-2-CHLOROISODURENE;α-2-Chloroisodurene;RARECHEM AL BD 0049;à(2)-chloroisodurene;Mesitylmethyl chloride
- CBNumber:
- CB9155491
- Molecular Formula:
- C10H13Cl
- Molecular Weight:
- 168.66
- MDL Number:
- MFCD00000901
- MOL File:
- 1585-16-6.mol
- MSDS File:
- SDS
| Melting point | 87-89 °C(lit.) |
|---|---|
| Boiling point | 140 °C15 mm Hg(lit.) |
| Density | 1.0131 (estimate) |
| refractive index | 1.5162 (estimate) |
| Flash point | 223 °F |
| storage temp. | Inert atmosphere,2-8°C |
| solubility | Chloroform (Sparingly), Ethyl Acetate (Slightly) |
| form | Fused Solid, Crystals, and/or Chunks |
| color | White |
| BRN | 386678 |
| Stability | Air Sensitive, Moisture Sensitive |
| InChI | 1S/C10H13Cl/c1-7-4-8(2)10(6-11)9(3)5-7/h4-5H,6H2,1-3H3 |
| InChIKey | UNRGEIXQCZHICP-UHFFFAOYSA-N |
| SMILES | Cc1cc(C)c(CCl)c(C)c1 |
| CAS DataBase Reference | 1585-16-6(CAS DataBase Reference) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS05 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H314 | |||||||||
| Precautionary statements | P260-P280-P303+P361+P353-P304+P340+P310-P305+P351+P338-P363 | |||||||||
| PPE | Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges | |||||||||
| Hazard Codes | C | |||||||||
| Risk Statements | 34-20/21/22 | |||||||||
| Safety Statements | 26-27-28-36/37/39-45-23 | |||||||||
| RIDADR | UN 3261 8/PG 2 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | DP1402000 | |||||||||
| HazardClass | 8 | |||||||||
| PackingGroup | II | |||||||||
| HS Code | 29036990 | |||||||||
| Storage Class | 8A - Combustible corrosive hazardous materials | |||||||||
| Hazard Classifications | Skin Corr. 1B | |||||||||
| Limited Quantities | 1 Kg (2.2 lbs) (solid) | |||||||||
| Excepted Quantities | Max Inner Pack (30g or 30ml) and Max Outer Pack (500g or 500ml) | |||||||||
| NFPA 704 |
|
alpha-2-Chloroisodurene price More Price(45)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 136980 | α2-Chloroisodurene 98% | 1585-16-6 | 5g | $124 | 2023-06-20 | Buy |
| TCI Chemical | T1763 | 2,4,6-Trimethylbenzyl Chloride | 1585-16-6 | 5G | $43 | 2026-04-30 | Buy |
| TCI Chemical | T1763 | 2,4,6-Trimethylbenzyl Chloride | 1585-16-6 | 25G | $140 | 2026-04-30 | Buy |
| TRC | TRC-T795955-5G | 2,4,6-Trimethylbenzyl Chloride | 1585-16-6 | 5g | $65 | 2026-06-03 | Buy |
| TRC | TRC-T795955-25G | 2,4,6-Trimethylbenzyl Chloride | 1585-16-6 | 25g | $199 | 2026-06-03 | Buy |
alpha-2-Chloroisodurene Chemical Properties, Uses, Production
Chemical Properties
white to light yellow crystal powde
Uses
2,4,6-Trimethylbenzyl Chloride (cas# 1585-16-6) is a compound useful in organic synthesis.
General Description
α2-Chloroisodurene undergoes coupling reaction with methylmagnesium iodide to yield 1,2-dimesitylethane.
Synthesis
4170-90-5
1585-16-6
General procedure for the synthesis of 2,4,6-trimethylbenzyl chloride from 2,4,6-trimethylbenzyl alcohol: 2,4,6-trimethylbenzyl alcohol (150 mg, 1.0 mmol) was dissolved in dichloromethane (DCM, 4 mL). Thionyl chloride (87 μL, 1.2 mmol) was added slowly at 0 °C. The reaction mixture was stirred for 1 h at room temperature. Upon completion of the reaction, the solvent was removed by distillation under reduced pressure to afford the target product 2,4,6-trimethylbenzyl chloride (168 mg, 100% yield) as a white powder. The product was identified by 1H NMR (300 MHz, CDCl3): δ 2.29 (s, 3H), 2.42 (s, 6H), 4.68 (s, 2H), 6.89 (s, 2H). Mass spectrometry analysis showed [M + H]+ peak at 133.
References
[1] Patent: WO2016/16238, 2016, A1. Location in patent: Page/Page column 126
[2] Beilstein Journal of Organic Chemistry, 2014, vol. 10, p. 1397 - 1405
[3] Organic Letters, 2002, vol. 4, # 11, p. 1975 - 1977
[4] Journal of Medicinal Chemistry, 1981, vol. 24, # 4, p. 382 - 389
[5] Synlett, 2014, vol. 25, # 18, p. 2639 - 2643
alpha-2-Chloroisodurene Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Changzhou Wanyao Biotechnology Co., Ltd. | 0519-89185693 15312551983 | 2410037592@qq.com | China | 280 | 55 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44852 | 61 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32273 | 50 |
| Shandong Xiya Chemical Co., Ltd | 13355009207 13355009207 | 3007715519@qq.com | China | 18722 | 57 |
View Latest Price from alpha-2-Chloroisodurene manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-02 | alpha-2-Chloroisodurene
1585-16-6
|
$1.00-100.00 | 1KG | 99% | Henan Fengda Chemical Co., Ltd | ||
 |
2025-05-23 | alpha-2-Chloroisodurene
1585-16-6
|
$50.00 | 1kg | 99 | 5000 | Hebei Zhuanglai Chemical Trading Co Ltd | |
 |
2020-01-09 | alpha-2-Chloroisodurene
1585-16-6
|
$9.80 | 1g | ≥99% | 100kg | Career Henan Chemical Co |
-
- alpha-2-Chloroisodurene
1585-16-6
- $1.00-100.00
- 99%
- Henan Fengda Chemical Co., Ltd
-
- alpha-2-Chloroisodurene
1585-16-6
- $50.00
- 99
- Hebei Zhuanglai Chemical Trading Co Ltd
-
- alpha-2-Chloroisodurene
1585-16-6
- $9.80
- ≥99%
- Career Henan Chemical Co
