Monensin
- CAS No.
- 17090-79-8
- Chemical Name:
- Monensin
- Synonyms
- MONENSIN SODIUM;a3823a;monelan;MONENSIN;Romensin;elancoban;Monensin A;MONENSIN NA;Monensin 20%;monensicacid
- CBNumber:
- CB9748019
- Molecular Formula:
- C36H62O11
- Molecular Weight:
- 670.87
- MDL Number:
- MFCD00799192
- MOL File:
- 17090-79-8.mol
- MSDS File:
- SDS
| Melting point | 103-105°C |
|---|---|
| alpha | D +47.7° |
| Boiling point | 608.24°C (rough estimate) |
| Density | 1.0773 (rough estimate) |
| refractive index | 1.5465 (estimate) |
| storage temp. | 2-8°C |
| pka | 6.6 (in 66% DMF) |
| CAS DataBase Reference | 17090-79-8(CAS DataBase Reference) |
| FDA 21 CFR | 556.420; 558.355; 558.4 |
| FDA UNII | 906O0YJ6ZP |
| EPA Substance Registry System | Monensin (17090-79-8) |
SAFETY
Risk and Safety Statements
| Hazard Codes | T |
|---|---|
| Risk Statements | 25 |
| Safety Statements | 36/37/39-45 |
| WGK Germany | 3 |
| RTECS | JH2830000 |
| Toxicity | LD50 of monensin complex in mice, chicks (mg/kg): 43.8 ± 5.2, 284 ± 47 orally (Haney, Hoehn) |
Monensin price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | M4900-01 | Monensin A | 17090-79-8 | 5mg | $362 | 2021-12-16 | Buy |
| Usbiological | M4435-02 | Monensin | 17090-79-8 | 500ul | $393 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb593405 | Monensin | 17090-79-8 | 50μg | $425 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0008060 | MONENSIN 95.00% | 17090-79-8 | 5MG | $497.06 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb593405 | Monensin | 17090-79-8 | 100μg | $635.8 | 2021-12-16 | Buy |
Monensin Chemical Properties,Uses,Production
Description
Monensin was found in the mycelium of Streptomyces cinnamonensis by Eli Lilly & Co. in 1967 in the course of screening for anticoccidial and growth-promoting substances for cattle, swine, and chickens. It shows antiprotozoal, antibacterial, and antifungal activities, as well as anticoccidial activity. Monensin is widely used to treat such infections and as a feed additive to promote the growth of livestock.
Chemical Properties
Crystallin Solid
Uses
Monensin A is a polyether antibiotic first isolated from Streptomyces cinnamonensis in 1967. Monensin A is a broad-spectrum anticoccicidial antibiotic, also exhibiting antifungal and antiviral activity. Monensin A forms complexes with monovalent cations such as Li+, Na+, K+, Rb+, Ag+ and Tl+ and is thus able to transport these cations across lipid membranes of cells, playing an important role as an Na+/H+ antiporter. It blocks intracellular protein transport and is used in animals to prevent coccidiosis, promote growth and prevent bloat. Derivatives of monensin, monensin methyl ester and particularly monensin decyl ester, are used in ion selective electrodes.
Uses
Poliether antibiotic. Coccidiostat
Uses
Monensin (2) C36H62O11, a carboxylic acid which is used as its water-soluble sodium salt (Coban, Rumensin). Monensin is also used to treat histomoniasis. The polyether ionophoric antibiotics are capable of complexing and interfacing with specific alkali metal cations to render them lipid-soluble and diffusible across parasite mitochondrial membranes. Related useful polyether antibiotics are narasin and lasalocid (3, Lasalocid A, C34H54O8,).
Definition
ChEBI: Monensin A is a spiroketal, monensin A is the major component of monensin, a mixture of antibiotic substances produced by Streptomyces cinnamonensis. An antiprotozoal, it is used as the sodium salt as a feed additive for the prevention of coccidiosis in poultry and as a growth promoter in cattle. It has a role as a coccidiostat, an antifungal agent and an ionophore. It is a monocarboxylic acid, a cyclic hemiketal, a spiroketal and a polyether antibiotic.
brand name
Coban [as sodium salt] (Lilly);Rumensin [as sodium salt] (Lilly).
Safety Profile
Poison by ingestion and intraperitoneal routes. An eye and skin irritant. When heated to decomposition it emits acrid smoke and irritating fumes.
Monensin Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| XI'AN TIANGUANGYUAN BIOTECH CO., LTD. | +86-029-86333380 18829239519 | sales06@tgybio.com | China | 959 | 58 |
| shandong perfect biotechnology co.ltd | +86-53169958659; +8618596095638 | sales@sdperfect.com | China | 294 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 7845 | 58 |
| Shaanxi TNJONE Pharmaceutical Co., Ltd | +8618740459177 | sarah@tnjone.com | China | 893 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21691 | 55 |
| Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 | fandachem@gmail.com | China | 9348 | 55 |
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3620 | 58 |
| Chengdu GLP biotechnology Co Ltd | 028-87075086 13350802083 | scglp@glp-china.com | CHINA | 1824 | 58 |
| Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 | sales@biopurify.com | China | 3424 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22968 | 58 |
View Lastest Price from Monensin manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-04-07 | Monensin
17090-79-8
|
US $0.00 / kg | 1kg | 99% | 1000kg | Shaanxi TNJONE Pharmaceutical Co., Ltd | |
 |
2024-03-23 | Monensin
17090-79-8
|
US $34.00-1.20 / kg | 1kg | 99% | g-kg-tons, free sample is available | Henan Fengda Chemical Co., Ltd | |
 |
2024-03-12 | Monensin
17090-79-8
|
US $0.00 / g | 1g | 98% HPLC | 100KG | shandong perfect biotechnology co.ltd |