ヘキサフルオロアセトン 化学特性,用途語,生産方法
用途
テトラフルオロエチレン、フッ化ビニル、フッ化ビニリデン、エチレンとの共重合体として用いる。ポリエチレン、ポリプロピレン、ポリブタジエン、アクリル、スチレン等へのヘキサフルオロプロパノールの側鎖導入剤、医薬品、農薬の合成原料
化学的特性
Hexafluoroacetone is a colorless, nonflamma ble poison gas. Musty odor. Shipped as a liquefied com pressed gas.
使用
Hexafluoroacetone is a protecting and activatng reagent used in the synthesis of (S)-isoserine from (S)-malic acid. It is also an intermediate used to prepare hexafluorocarbinols as liver X receptor-α agonists.
定義
ChEBI: A ketone that is acetone in which all the methyl hydrogens are replaced by fluoro groups.
一般的な説明
Hexafluoroacetone is a colorless, toxic, and highly reactive gas. At ambient temperatures, Hexafluoroacetone is likely to generate a considerable amount of vapor. Hexafluoroacetone is an irritant to skin, eyes and mucous membranes and is toxic by ingestion, skin absorption, and inhalation. When heated to high temperatures Hexafluoroacetone emits toxic fluoride fumes. Prolonged exposure of the container to fire or intense heat may cause Hexafluoroacetone to violently rupture and rocket. Hexafluoroacetone is used in the production of other chemicals.
空気と水の反応
Hygroscopic (i.e., absorbs moisture from the air); reacts with moisture to form a highly acidic sesquihydrate. .
反応プロフィール
Hexafluoroacetone is incompatible with the following: Water, acids [Note: Hygroscopic (i.e., absorbs moisture from the air); reacts with moisture to form a highly acidic sesquihydrate.] .
危険性
Toxic by inhalation and skin absorption.
Reacts vigorously with water and other substances,
releasing considerable heat. Nonflammable.
健康ハザード
TOXIC; may be fatal if inhaled, ingested or absorbed through skin. Vapors are extremely irritating and corrosive. Contact with gas or liquefied gas may cause burns, severe injury and/or frostbite. Fire will produce irritating, corrosive and/or toxic gases. Runoff from fire control may cause pollution.
火災危険
Some may burn but none ignite readily. Vapors from liquefied gas are initially heavier than air and spread along ground. Some of these materials may react violently with water. Cylinders exposed to fire may vent and release toxic and/or corrosive gas through pressure relief devices. Containers may explode when heated. Ruptured cylinders may rocket.
職業ばく露
Hexafluoroacetone is used as a chemi cal intermediate. A gas at room temperature, it forms vari ous hydrates with water which are used as solvents for
resins and polymers. Other derivatives are used to make
water repellent coatings for textiles and also to produce
polymers.
輸送方法
UN2420 Hexafluoroacetone, Hazard Class: 2.3;
Labels: 2.3-Poisonous gas, 8-Corrosive material, Inhalation
Hazard Zone B. Cylinders must be transported in a secure
upright position, in a well-ventilated truck. Protect cylinder
and labels from physical damage. The owner of the com pressed gas cylinder is the only entity allowed by federal
law (49CFR) to transport and refill them. It is a violation
of transportation regulations to refill compressed gas cylin ders without the express written permission of the owner.
純化方法
Dehydrate hexafluoroacetone by passing the vapours over P2O5. Ethylene is removed by passing the dried vapours through a tube containing Pyrex glass wool moistened with conc H2SO4. Further purification is by low temperature distillation using Warde-Le Roy stills. Store it in the dark at -78o. [Holmes & Kutschke Trans Faraday Soc 58 333 1962, Beilstein 1 IV 3215.]
不和合性
Reacts with water, oxidizers, strong
acids. Hygroscopic (i.e., absorbs moisture from the air);
reacts with moisture to form a highly acidic sesquihydrate
and considerable heat.
廃棄物の処理
Return refillable compressed
gas cylinders to supplier. Nonrefillable cylinders should be
disposed of in accordance with local, state and federal
regulations. Allow remaining gas to vent slowly into
atmosphere in an unconfined area or exhaust hood.
Refillable-type cylinders should be returned to original sup plier with any valve caps and outlet plugs secured and
valve protection caps in place.
ヘキサフルオロアセトン 上流と下流の製品情報
原材料
ヘキサフルオロアセトン 水和物
1,1,2,3,3,3-ヘキサフルオロ-1,2-エポキシプロパン
2-トリフルオロメチル-1,1,3,3,3-ペンタフルオロ-1-プロペン
テトラフルオロエテン
過マンガン酸カリウム
準備製品