Methyl 3-amino-4-methylthiophene-2-carboxylate
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Methyl 3-amino-4-methylthiophene-2-carboxylate 속성
- 녹는점
- 85-88 °C (lit.)
- 끓는 점
- 318.6±37.0 °C(Predicted)
- 밀도
- 1.264±0.06 g/cm3(Predicted)
- 인화점
- >100°C
- 저장 조건
- Keep in dark place,Sealed in dry,Room Temperature
- 용해도
- 클로로포름(약간 용해됨), 메탄올(약간 용해됨)
- 산도 계수 (pKa)
- 1.71±0.10(Predicted)
- 물리적 상태
- 고체
- 물리적 상태
- 단단한 모양
- 색상
- 옅은 노랑
- 수용성
- 1g/L at 35℃
- BRN
- 973196
- InChIKey
- YICRPERKKBDRSP-UHFFFAOYSA-N
- LogP
- 1.28
- CAS 데이터베이스
- 85006-31-1(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
위험품 표기 | Xi | ||
---|---|---|---|
위험 카페고리 넘버 | 36/37/38 | ||
안전지침서 | 26-36-24/25-22 | ||
WGK 독일 | 2 | ||
위험 참고 사항 | Irritant | ||
HS 번호 | 29349990 |
Methyl 3-amino-4-methylthiophene-2-carboxylate C화학적 특성, 용도, 생산
화학적 성질
white to light yellow crystal powder용도
Methyl 3-Amino-4-methylthiophene-2-carboxylate is a versatile reactant used in various syntheses. It is used in the preparation of (oxalylamino)benzoic acids and (carboxyheteroarylamino)oxalic acids as selective and orally bioavailable nonpeptide inhibitors of protein-tyrosine phosphatase 1B.주요 응용
methyl 3-amino-4-methylthiophene-2-carboxylate is the starting material used in the synthesis of the local anesthetic articaine.7-Methylthieno[3,2-d]pyrimidin-4(3H)-one was prepared using methyl 3-amino-4-methylthiophene-2-carboxylate.
The reaction of 4-bromotoluene (0.171 g, 1 mmol), methyl 3-amino-4-methylthiophene-2-carboxylate(0.342 g, 2 mmol) and KOAc (0.196 g, 2 mmol) in the presence of PdCl(C3H5)(dppb) (12.2 mg, 0.02mmol) in DMAc at 120 °C affords the corresponding Methyl 3-amino-4-methyl-5-p-tolylthiophene-2-carboxylate in 81% (0.212 g) isolated yield.
Methyl 3-amino-4-methylthiophene-2-carboxylate 준비 용품 및 원자재
원자재
메틸티오글라이콜레이트
수소화나트륨
에틸알코올
염산 히드록실아민
메틸메타크릴레이트
메틸2-메틸-3-옥소-테트라히드로티오펜-2-탄산염
4-메틸-3-아미노-2-(메톡시카르보닐)-4,5-디히드로티오펜
준비 용품
Methyl 3-amino-4-methylthiophene-2-carboxylate 공급 업체
글로벌( 406)공급 업체
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Hebei Xinsheng New Material Technology Co., LTD. | +86-16632316109 |
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Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
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Beijing Cooperate Pharmaceutical Co.,Ltd | 010-60279497 |
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Hi-Tech Chemistry Corp | 0519-86626038 |
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Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 |
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career henan chemical co | +86-0371-86658258 +8613203830695 |
sales@coreychem.com | China | 29888 | 58 |