말로닐우레아
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말로닐우레아 속성
- 녹는점
- 248-252 °C (dec.) (lit.)
- 끓는 점
- 260℃ (decomposition)
- 밀도
- 1.6006 (rough estimate)
- 굴절률
- 1.4610 (estimate)
- 인화점
- 150 °C
- 저장 조건
- Store below +30°C.
- 용해도
- 11.45g/L
- 물리적 상태
- 분말/고체
- 산도 계수 (pKa)
- 4.01(at 25℃)
- 색상
- 가벼운 크림
- 냄새
- 냄새 없는
- 수소이온지수(pH)
- 2-3 (50g/l, H2O, 60℃)
- 수용성
- 142g/L(20℃)
- Merck
- 14,963
- BRN
- 120502
- InChIKey
- HNYOPLTXPVRDBG-UHFFFAOYSA-N
- CAS 데이터베이스
- 67-52-7(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 위험 카페고리 넘버 | 36/37/38 | ||
|---|---|---|---|
| 안전지침서 | 24/25 | ||
| WGK 독일 | 1 | ||
| RTECS 번호 | CP8000000 | ||
| TSCA | Yes | ||
| HS 번호 | 29335200 | ||
| 독성 | LD50 orally in Rabbit: > 5000 mg/kg | ||
| 기존화학 물질 | KE-34294 97-3-1 |
말로닐우레아 C화학적 특성, 용도, 생산
화학적 성질
cream coloured fine crystalline powder. Odorless. Soluble in water and ether, insoluble in water and alcohol.정의
ChEBI: Barbituric acid is a barbiturate, the structure of which is that of perhydropyrimidine substituted at C-2, -4 and -6 by oxo groups. Barbituric acid is the parent compound of barbiturate drugs, although it is not itself pharmacologically active. It has a role as an allergen and a xenobiotic. It is a conjugate acid of a barbiturate, a barbiturate(2-) and a barbiturate(1-).제조 방법
Barbituric acid is derived By the reaction of diethyl malonate and urea. First put Urea in a reaction tank containing methanol ,heat , reflux , dissolve, then add the dried diethyl malonate and sodium methoxide, the reaction is refluxed at 66-68°C for 4-5h, after distillation to recover methanol, cooling to 40-50°C, add dilute hydrochloric acid to adjust to pH 1-2.Cool to room temperature, throw to obtain crude, wash with distilled water once, dry to get crude , and then purify with water and activated carbon, dry to obtain products. Industrial barbituric acid is white or pink crystalline powder, strongly acidic, more than 98% content, melting point ≥245°C. Material consumption fixed: diethyl malonate 1098kg/t, urea 476kg/t, hydrochloric acid (reagent grade III) 681kg/t, sodium methanol (28%) 369kg/t, methanol 1025kg/t.화학 반응
Barbituric acid with aromatic aldehydes was used in an experimental study, meant to demonstrate the increased efficiency of Knoevenagel condensation reaction for barbituric acid and various aromatic aldehydes on basic alumina, in the absence of organic solvents under microwave irradiation. It may also be used in electrochemical oxidation of iodine, using cyclic voltammetry and controlled-potential coulometry.일반 설명
Barbituric acid is a useful acid for organic and drug syntheses. Its dihydrate form can be synthesized from barbituric acid via crystallization from aqueous solution. Crystal structure of barbituric acid (in tautomeric form) has been investigated by a three dimensional fourier transform method. Its enol crystal form has been reported to be thermodynamically stable.Purification Methods
Recrystallise it twice from H2O, then dry it for 2 days at 100o. [Beilstein 24 III/IV 1873.]말로닐우레아 준비 용품 및 원자재
원자재
Diethyl ester
메틸산 나트륨
Dilute hydrochloric acid
말론산
5-FLUORODIHYDRO-6-HYDROXY-2,4-(1H,3H)-PYRIMIDINEDIONE
준비 용품
Vitamin B2
2,4,6-TRICHLOROPYRIMIDIN-5-AMINE
5-BROMO-6-HYDROXY-1H-PYRIMIDINE-2,4-DIONE
2,4,6-TRIBROMOPYRIMIDINE
리보플라빈
5-NITROBARBITURIC ACID
디에틸바비틀산 나트륨
N-(2-Amino-4,6-dichloro-5-pyrimidinyl)formamide
URAMIL
ALLOXAN MONOHYDRATE
1,3-디(2,4,6-트리옥소헥사히드로-5-피리미딘일리덴)아이소인돌
6-BROMO-2,4-DIMETHOXYPYRIMIDINE
2,4,6-TRICHLORO-5-NITROPYRIMIDINE
2,4,6-트리아미노피리미딘
리보플라빈부틸산에스테르
C.I. 염료 황색 185
6-Chlorouracil
2,4,6-TRIMETHOXYPYRIMIDINE
DIRECT YELLOW 147
말로닐우레아 공급 업체
글로벌( 547)공급 업체
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| Shanxi Naipu Import and Export Co.,Ltd | +86-13734021967 +8613734021967 |
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