BACAMPICILLIN

BACAMPICILLIN 구조식 이미지
카스 번호:
50972-17-3
상품명:
BACAMPICILLIN
동의어(영문):
Carampicillin;BACAMPICILLIN;BACAMPICILLIN USP/EP/BP;BACAMPICILLIN HCL USP(CRM STANDARD);Bacampicillin (base and/or unspecified salts);6α-[[(R)-2-Amino-2-phenylacetyl]amino]penicillanic acid 1-[(ethoxycarbonyl)oxy]ethyl ester;(2S,5R,6R)-6-[[(2R)-2-Amino-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 1-(ethoxycarbonyloxy)ethyl ester;4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[(2R)-aminophenylacetyl]amino]-3,3-dimethyl-7-oxo-, 1-[(ethoxycarbonyl)oxy]ethyl ester, (2S,5R,6R)-;(2S,5R,6R)-6-[[(2R)-2-amino-1-oxo-2-phenylethyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 1-ethoxycarbonyloxyethyl ester;4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[(aminophenylacetyl)amino]-3,3-dimethyl-7-oxo-, 1-[(ethoxycarbonyl)oxy]ethyl ester, [2S-[2α,5α,6β(S*)]]-
CBNumber:
CB1343108
분자식:
C21H27N3O7S
포뮬러 무게:
465.52
MOL 파일:
50972-17-3.mol

BACAMPICILLIN 속성

끓는 점
678.4±55.0 °C(Predicted)
밀도
1.37±0.1 g/cm3(Predicted)
저장 조건
Store at -20°C
용해도
DMSO에 용해됨
산도 계수 (pKa)
pKa 6.8 (Uncertain)
CAS 데이터베이스
50972-17-3

안전

BACAMPICILLIN C화학적 특성, 용도, 생산

정의

ChEBI: A penicillanic acid ester that is the 1-ethoxycarbonyloxyethyl ester of ampicillin. It is a semi-synthetic, microbiologically inactive prodrug of ampicillin.

신진 대사

Although comparatively well absorbed (30–55%), the oral efficacy of ampicillin for systemic infections can be enhanced significantly through the preparation of pro-drugs. In contrast to ampicillin itself, which is amphoteric, bacampicillin is a weak base and is very well absorbed in the duodenum (80–98%). Enzymatic ester hydrolysis in the gut wall liberates carbon dioxide and ethanol, followed by spontaneous loss of acetaldehyde and production of ampicillin. The acetaldehyde is metabolized oxidatively by alcohol dehydrogenase to produce acetic acid, which joins the normal metabolic pool.

BACAMPICILLIN 준비 용품 및 원자재

원자재

준비 용품


BACAMPICILLIN 공급 업체

글로벌( 32)공급 업체
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Shaanxi Dideu Medichem Co. Ltd
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TargetMol Chemicals Inc.
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Career Henan Chemica Co
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Shaanxi Dideu Medichem Co. Ltd
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BOC Sciences
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Amadis Chemical Company Limited
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sales@amadischem.com China 131981 58
Beijing HuaMeiHuLiBiological Chemical 010-56205725
waley188@sohu.com China 12338 58
MedChemexpress LLC 021-58955995
sales@medchemexpress.cn United States 4863 58
Musechem +1-800-259-7612
info@musechem.com United States 4662 60
Shanghai Han-Xiang Chemical Co., Ltd. 15971444841
amber@biochempartner.com China 3063 58

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