Pomalidomide-PEG5-CO2H
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Pomalidomide-PEG5-CO2H 속성
- 끓는 점
- 791.0±60.0 °C(Predicted)
- 밀도
- 1.360±0.06 g/cm3(Predicted)
- 저장 조건
- 2-8°C
- 산도 계수 (pKa)
- 4.28±0.10(Predicted)
- 물리적 상태
- Solid-Liquid Mixture
- 색상
- White to yellow
안전
Pomalidomide-PEG5-CO2H C화학적 특성, 용도, 생산
용도
Protein degrader builiding block Pomalidomide-PEG5-CO2H enables the synthesis of molecules for targeted protein degradation and PROTAC (proteolysis-targeting chimeras) technology. This conjugate contains a Cereblon (CRBN)-recruiting ligand and a PEGylated crosslinker with pendant carboxylic acid for reactivity with an amine on the target ligand. Because even slight alterations in ligands and crosslinkers can affect ternary complex formation between the target, E3 ligase, and PROTAC, many analogs are prepared to screen for optimal target degradation. When used with other protein degrader building blocks with a pendant carboxyl group, parallel synthesis can be used to more quickly generate PROTAC libraries that feature variation in crosslinker length, composition, and E3 ligase ligand.Pomalidomide-PEG5-CO2H 준비 용품 및 원자재
원자재
준비 용품
Pomalidomide-PEG5-CO2H 공급 업체
글로벌( 41)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| BOC Sciences | +1-631-485-4226 |
inquiry@bocsci.com | United States | 19552 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 |
1026@dideu.com | China | 20284 | 58 |
| Henan Alfa Chemical Co., Ltd | +8615838112936 |
alfa10@alfachem.cn | China | 12921 | 58 |
| HANGZHOU LEAP CHEM CO., LTD. | +86-571-87711850 |
market18@leapchem.com | China | 43339 | 58 |
| Nanjing Bicbiotechnology Co., Ltd | +86-2552131256 +86-18251840740 |
sales@bicbiotech.com | China | 5994 | 58 |
| Xian confluore Biological Technology Co., Ltd. | +86-15680926068 |
1924344760@confluore.cn | China | 2997 | 58 |
| Aladdin Scientific | |
tp@aladdinsci.com | United States | 57505 | 58 |
| Shanghai Aladdin Bio-Chem Technology Co.,LTD | 400-6206333 13167063860 |
anhua.mao@aladdin-e.com | China | 25003 | 65 |
| Mashilabs (Shanghai) Co.,Ltd. | 19916721580 |
mafarm@126.com | China | 4542 | 58 |
| Sigma-Aldrich | 021-61415566 800-8193336 |
orderCN@merckgroup.com | China | 51395 | 80 |
Pomalidomide-PEG5-CO2H 관련 검색:
Pomalidomide-PEG3-CO2H
E3 Ligase Ligand-Linker Conjugates 1
POMALIDOMIDE-PEG2-CO2H
Pomalidomide-PEG1-azide
Pomalidomide-O-C4-NH2
Propanoic acid, 3-[[17-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]-3,6,9,12,15-pentaoxaheptadec-1-yl]oxy]-
Pomalidomide-PEG3-N3
Pomalidomide-PEG6-butyl iodide
POMALIDOMIDE-PEG1-CO2H
Pomalidomide-PEG3-Amine HCl salt
Pomalidomide-PEG4-CO2H
4-((2-(2-(2-(2-aminoethoxy)ethoxy)ethoxy)ethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione
E3 Ligase Ligand-Linker Conjugates 22
Pomalidomide-PEG2-butyl iodide
Pomalidomide-PEG4-azide
Pomalidomide-PEG2-N3
E3 ligase Ligand-Linker Conjugates 50
POMALIDOMIDE-PEG1-ALKYNE