Pomalidomide-PEG2-N3
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Pomalidomide-PEG2-N3 속성
- 녹는점
- 188 °C
- 저장 조건
- 2-8°C
- 용해도
- DMSO: 90 mg/mL (202.52 mM)
안전
Pomalidomide-PEG2-N3 C화학적 특성, 용도, 생산
용도
Protein degrader builiding block Pomalidomide-PEG2-azide enables the synthesis of molecules for targeted protein degradation and PROTAC (proteolysis-targeting chimeras) technology. This conjugate contains a Cereblon (CRBN)-recruiting ligand and a PEGylated crosslinker with pendant azide for click chemistry with a target ligand. Because even slight alterations in ligands and crosslinkers can affect ternary complex formation between the target, E3 ligase, and PROTAC, many analogs are prepared to screen for optimal target degradation. When used with other protein degrader building blocks with a pendant azide group, parallel synthesis can be used to more quickly generate PROTAC libraries that feature variation in crosslinker length, composition, and E3 ligase ligand.Pomalidomide-PEG2-N3 준비 용품 및 원자재
원자재
준비 용품
Pomalidomide-PEG2-N3 공급 업체
글로벌( 13)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
Xian confluore Biological Technology Co., Ltd. | +86-15680926068 +86-15680926068 |
1924344760@confluore.cn | China | 2893 | 58 |
Aladdin Scientific | +1-833-552-7181 |
sales@aladdinsci.com | United States | 57511 | 58 |
Shanghai Chaolan Chemical Technology Center | QQ:65489617 15618227136 |
info@SuperLan-chem.com | China | 9445 | 58 |
Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 18892239720 |
psaitong@jm-bio.com | China | 12308 | 58 |
Xi'an Confluore Biological Technology Co., Ltd. | +86-156-80926068 +86-15680926068 |
1924344760@qq.com | China | 4955 | 58 |
Jiangsu aikang biomedical research and development co., LTD | 025-66110311 13155353615 |
qzhang@aikonchem.com | China | 15527 | 58 |
Jilin Province Woda Biotechnology Co., Ltd. | 13504435624 |
1927928688@qq.com | China | 1290 | 58 |
Shaanxi borno biotechnology co., LTD | +86-13759708231 |
asherw9@hotmail.com | China | 2351 | 58 |
Shanghai Kaiwei Chemical Technology Co., Ltd. | 021-58461859 15821823057 |
service@aiviche.com | China | 49323 | 58 |
Shanghai Haohong Pharmaceutical Co., Ltd. | 400-8210725 4008210725 |
malulu@leyan.com | China | 39997 | 58 |
Pomalidomide-PEG2-N3 관련 검색:
Pomalidomide-PEG1-azide
Pomalidomide-PEG3-N3
E3 ligase Ligand-Linker Conjugates 50
Pomalidomide-PEG3-CO2H
Pomalidomide-PEG4-azide
E3 Ligase Ligand-Linker Conjugates 22
4-((2-(2-(2-(2-aminoethoxy)ethoxy)ethoxy)ethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione
Pomalidomide-PEG4-CO2H
E3 Ligase Ligand-Linker Conjugates 1
POMALIDOMIDE-PEG2-CO2H
Pomalidomide-PEG5-CO2H
POMALIDOMIDE-PEG1-CO2H
Pomalidomide-O-C4-NH2
Propanoic acid, 3-[[17-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]-3,6,9,12,15-pentaoxaheptadec-1-yl]oxy]-
Pomalidomide-PEG6-butyl iodide
Pomalidomide-PEG2-butyl iodide
Pomalidomide-NH-CO-PEG6-N3
Pomalidomide-PEG5-N3