Isepamicine
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Isepamicine 속성
- 끓는 점
- 633.08°C (rough estimate)
- 밀도
- 1.3531 (rough estimate)
- 굴절률
- 1.7500 (estimate)
- 산도 계수 (pKa)
- 11.01±0.35(Predicted)
안전
Isepamicine C화학적 특성, 용도, 생산
개요
Isepamicin is a aminoglycoside antibiotic indicated for use in the treatment of urinary and respiratory tract infections. Although it is less potent than most other aminoglycosides, it is also less nephrotoxic. The broad-spectrum activity of isepamicin generally parallels that of amikacin in vitro.용도
Antibacterial (aminoglyco side).Antimicrobial activity
Hydroxyamino propionyl gentamicin B. A semisynthetic derivative of gentamicin B, modified to render it more resistant to microbial inactivation.In-vitro activity is comparable to or slightly greater than amikacin against Staph. aureus and most enterobacteria; it is much more active against Ser. marcescens, Enterobacter spp. and Klebsiebella pneumoniae. It is also active in vitro against the Mycobacterium avium complex and Nocardia asteroides. It is less susceptible than amikacin or gentamicin to inactivation by β-lactam antibiotics. It retains activity against some strains resistant to most other aminoglycosides.
Pharmacokinetics in neonatal, pediatric, adult, elderly and renally impaired patients are similar to those of other aminoglycosides. In adult volunteers the plasma half-life was 2.1 h. Clearance is reduced in neonates and the elderly. A 7.5 mg/kg once-daily dosage is recommended for children less than 16 days old. No dosage adjustment is required for the elderly unless renal function is impaired. Clearance is proportional to creatinine clearance in patients with chronic renal impairment, and it is eliminated by hemodialysis.
It has been used in respiratory tract infections, urinary tract infections and intra-abdominal infections, in adults and children. It appears to be as effective and well tolerated as amikacin. It is available in Japan.
Isepamicine 준비 용품 및 원자재
원자재
준비 용품
Isepamicine 공급 업체
글로벌( 74)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
CONIER CHEM AND PHARMA LIMITED | +8618523575427 |
sales@conier.com | China | 49390 | 58 |
career henan chemical co | +86-0371-86658258 15093356674; |
factory@coreychem.com | China | 29826 | 58 |
Shaanxi Dideu Medichem Co. Ltd | +86-29-87569265 +86-18612256290 |
1056@dideu.com | China | 3581 | 58 |
Hubei Ipure Biology Co., Ltd | +8613367258412 |
ada@ipurechemical.com | China | 10326 | 58 |
Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418671 |
sales@tnjchem.com | China | 34572 | 58 |
Shaanxi Dideu Medichem Co. Ltd | +86-029-89586680 +86-18192503167 |
1026@dideu.com | China | 9320 | 58 |
Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 |
1026@dideu.com | China | 29220 | 58 |
Hebei Duling International Trade Co. LTD | +8618032673083 |
sales05@hbduling.cn | China | 15745 | 58 |
ZHEJIANG JIUZHOU CHEM CO., LTD | +86-0576225566889 +86-13454675544 |
admin@jiuzhou-chem.com;jamie@jiuzhou-chem.com;alice@jiuzhou-chem.com | China | 20000 | 58 |
GIHI CHEMICALS CO.,LIMITED | +8618058761490 |
info@gihichemicals.com | China | 49999 | 58 |
Isepamicine 관련 검색:
6-아미노 카프로산 트리스(하이드록시메틸)아미노메탄 글리신 3-아미노프로필-N-시클로헥실아민
ALTRENOGEST
Omeprazole magnesium
Isepamicin sulfate
Miboplatin
GENTAMICIN B
4-ACETAMIDOCYCLOHEXANOL
4-O-(6-Amino-6-deoxy-α-D-glucopyranosyl)-2-deoxy-D-streptamine
(1R,2R)-2-(PROPYLAMINO)CYCLOHEXANOL
(1R,2R)-2-(ETHYLAMINO)CYCLOHEXANOL
METHYL 6-AMINO-6-DEOXY-GALACTOPYRANOSIDE
AMINO ACIDS
Isepamicine
METHYL 6-AMINO-6-DEOXY-GALACTOPYRANOSIDE
Nojirimycin