Isepamicine
- CAS No.
- 58152-03-7
- Chemical Name:
- Isepamicine
- Synonyms
- hapa-b;sch21420;isepamicin;ISEPAMICINE;hapa-gentamycinb;ISEPAMICIN SULPHATE;Isepamicine USP/EP/BP;(s)-y-1-oxopropyl)-2-deoxy;Isepamicin Sulfate Impurity Ⅲ:Isepamicine;Isepamicin Sulfate Impurity Ⅲ:Isepamicine
- CBNumber:
- CB3245233
- Molecular Formula:
- C22H43N5O12
- Molecular Weight:
- 569.6
- MDL Number:
- MFCD00864928
- MOL File:
- 58152-03-7.mol
Boiling point | 633.08°C (rough estimate) |
---|---|
Density | 1.3531 (rough estimate) |
refractive index | 1.7500 (estimate) |
pka | 11.01±0.35(Predicted) |
FDA UNII | G7K224460P |
ATC code | J01GB11 |
Isepamicine price
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Biorbyt Ltd | orb134569 | Isepamicin >99% | 58152-03-7 | 100mg | $510 | 2021-12-16 | Buy |
Biorbyt Ltd | orb134569 | Isepamicin >99% | 58152-03-7 | 250mg | $765 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | ING0005409 | ISEPAMICIN 95.00% | 58152-03-7 | 250MG | $1146.05 | 2021-12-16 | Buy |
Biorbyt Ltd | orb134569 | Isepamicin >99% | 58152-03-7 | 1g | $1504.5 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | ING0005409 | ISEPAMICIN 95.00% | 58152-03-7 | 1G | $1758.49 | 2021-12-16 | Buy |
Isepamicine Chemical Properties,Uses,Production
Description
Isepamicin is a aminoglycoside antibiotic indicated for use in the treatment of urinary and respiratory tract infections. Although it is less potent than most other aminoglycosides, it is also less nephrotoxic. The broad-spectrum activity of isepamicin generally parallels that of amikacin in vitro.
Originator
Schering Plough (USA)
Uses
Antibacterial (aminoglyco side).
brand name
Isepacin; Exacin
Antimicrobial activity
Hydroxyamino propionyl gentamicin B. A semisynthetic
derivative of gentamicin B, modified to render it more resistant
to microbial inactivation.
In-vitro activity is comparable to or slightly greater than
amikacin against Staph. aureus and most enterobacteria; it is
much more active against Ser. marcescens, Enterobacter spp.
and Klebsiebella pneumoniae. It is also active in vitro against
the Mycobacterium avium complex and Nocardia asteroides. It
is less susceptible than amikacin or gentamicin to inactivation
by β-lactam antibiotics. It retains activity against some strains
resistant to most other aminoglycosides.
Pharmacokinetics in neonatal, pediatric, adult, elderly and
renally impaired patients are similar to those of other aminoglycosides.
In adult volunteers the plasma half-life was 2.1 h.
Clearance is reduced in neonates and the elderly. A 7.5 mg/kg
once-daily dosage is recommended for children less than 16
days old. No dosage adjustment is required for the elderly unless
renal function is impaired. Clearance is proportional to creatinine
clearance in patients with chronic renal impairment, and it
is eliminated by hemodialysis.
It has been used in respiratory tract infections, urinary
tract infections and intra-abdominal infections, in adults and
children. It appears to be as effective and well tolerated as
amikacin. It is available in Japan.
Isepamicine Preparation Products And Raw materials
Isepamicine Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49392 | 58 |
career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29822 | 58 |
Hubei Ipure Biology Co., Ltd | +8613367258412 | ada@ipurechemical.com | China | 10326 | 58 |
Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34571 | 58 |
Shaanxi Dideu Medichem Co. Ltd | +86-029-89586680 +86-18192503167 | 1026@dideu.com | China | 7830 | 58 |
GIHI CHEMICALS CO.,LIMITED | +8618058761490 | info@gihichemicals.com | China | 50003 | 58 |
Beijing HuaMeiHuLiBiological Chemical | 010-56205725 | waley188@sohu.com | China | 12338 | 58 |
Shanghai T&W Pharmaceutical Co., Ltd. | +86 21 61551611 | China | 9900 | 58 | |
AdooQ BioScience, LLC | +1 (866) 930-6790 | info@adooq.com | United States | 2784 | 58 |
ChemStrong Scientific Co.,Ltd | 0755-0755-66853366 13670046396 | sales@chem-strong.com | China | 18021 | 56 |
Related articles
- Clinical Uses of Isepamicin
- Isepamicin is inactivated less than gentamicin by high concentration of various penicillins and beta-lactamase inhibitors.
- Mar 15,2022
View Lastest Price from Isepamicine manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2021-07-02 | Isepamicine
58152-03-7
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd | ||
2020-01-13 | isepamicin
58152-03-7
|
US $1.00 / g | 1g | 95-99% | 1ton | Career Henan Chemical Co | ||
2020-01-13 | Isepamicine
58152-03-7
|
US $1.00 / g | 1g | 99% | 200kg | Career Henan Chemical Co |
- Isepamicine
58152-03-7
- US $15.00-10.00 / KG
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
- isepamicin
58152-03-7
- US $1.00 / g
- 95-99%
- Career Henan Chemical Co
- Isepamicine
58152-03-7
- US $1.00 / g
- 99%
- Career Henan Chemical Co