beta-Cyclodextrin hydrate

beta-Cyclodextrin hydrate 구조식 이미지
카스 번호:
68168-23-0
상품명:
beta-Cyclodextrin hydrate
동의어(영문):
CD;β-CycL;U in HNO3 1%;odextrin hydrate;CYCLOHEPTAAMYLOSE;10ug/l each of Ba;Cyclodextrin,Hydrate;schardinger á-dextrin;á-cyclodextrin hydrate;B-CYCLODEXTRIN HYDRATE
CBNumber:
CB3270383
분자식:
C42H70O35
포뮬러 무게:
1134.98
MOL 파일:
68168-23-0.mol
MSDS 파일:
SDS

beta-Cyclodextrin hydrate 속성

녹는점
>260 °C (dec.)(lit.)
알파
161 º (c=1, H2O 25 ºC)
저장 조건
Refrigerator
용해도
물(약간 용해됨)
물리적 상태
결정성 분말
색상
하얀색
optical activity
[α]20/D +142°, c = 1 in H2O (Dry basis)
수용성
18.5g/L(25℃)
Merck
14,2718
BRN
5915513
안전
  • 위험 및 안전 성명
안전지침서 24/25
WGK 독일 2
RTECS 번호 GU2293000
TSCA Yes
HS 번호 35051000
그림문자(GHS):
신호 어:
유해·위험 문구:
암호 유해·위험 문구 위험 등급 범주 신호 어 그림 문자 P- 코드
예방조치문구:
NFPA 704
1
0 0

beta-Cyclodextrin hydrate C화학적 특성, 용도, 생산

개요

β-Cyclodextrin (β-CD) is a cyclic oligosaccharide that contains seven D-(+)-glucopyranose units and has been used to improve the aqueous solubility of various compounds, especially those containing a phenyl group. The circular arrangement of its glucose units produces a torus-shaped ring configuration in which the CH2 groups and ether linkages of the molecule face the hollow interior, resulting in a nonpolar, hydrophobic cavity and a polar, hydrophilic exterior. When combined in solution with other compounds, the nonpolar aromatic portions of that compound interact with the nonpolar interior of the β-CD molecule, thus isolating the aromatic portion of the molecule from the water and thereby increasing its aqueous solubility.

화학적 성질

white crystalline powder

용도

beta-Cyclodextrin hydrate forms clathrates. Produces a water-soluble complex with dansyl chloride for the fluorescent labeling of proteins. It is used in pharmaceutical research, as pharmaceutical intermediates and also as chemical reagents.

일반 설명

β-cyclodextrin (β-CD), a well-known macrocyclic oligosaccharide member of the CD family, is composed of seven D-glucose units connected via α(1→4) glycosidic bonds. Its ability to form several inclusion complexes with organic as well as inorganic compounds makes it a potential candidate in solid and solution state determinations.

Purification Methods

Recrystallise β-cyclodextrin from water and dry it for 12hours in a vacuum at 110o, or 24hours in a vacuum at 70o. The purity is assessed by TLC on cellulose containing a fluorescent indicator. [Taguchi, J Am Chem Soc 108 2705 1986, Tabushi et al. J Am Chem Soc 108 4514 1986, Orstam & Ross J Phys Chem 91 2739 1987.] [Beilstein 19 IV 6287, 19/12 V 801.]

beta-Cyclodextrin hydrate 준비 용품 및 원자재

원자재

준비 용품


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