Cetirizine
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Cetirizine 속성
- 녹는점
- 110-115°C
- 끓는 점
- 542.1±45.0 °C(Predicted)
- 밀도
- 1.237±0.06 g/cm3(Predicted)
- 저장 조건
- 2-8°C
- 용해도
- insoluble in EtOH; ≥122 mg/mL in H2O; ≥19.44 mg/mL in DMSO
- 물리적 상태
- 고체
- 물리적 상태
- 단단한 모양
- 산도 계수 (pKa)
- 3.46±0.10(Predicted)
- 수용성
- 101mg/L
- CAS 데이터베이스
- 83881-51-0(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| WGK 독일 | 3 | ||
|---|---|---|---|
| RTECS 번호 | AG0977500 | ||
| 유해 물질 데이터 | 83881-51-0(Hazardous Substances Data) |
| 그림문자(GHS): |
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| 신호 어: | Warning | |||||||||||||||||||||||||||||||||||
| 유해·위험 문구: |
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| 예방조치문구: |
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Cetirizine C화학적 특성, 용도, 생산
화학적 성질
white, crystalline powder용도
Cetirizine is a metabolite of the first-generation H1 antihistamine hydroxyzine. A reduced dosage (5 mg daily) is recommended in patients with chronic renal or hepatic impairment. Sedative side effects increase with dosages of cetirizine >10 mg per day.정의
ChEBI: A member of the class of piperazines that is piperazine in which the hydrogens attached to nitrogen are replaced by a (4-chlorophenyl)(phenyl)methyl and a 2-(carboxymethoxy)ethyl group respectively.일반 설명
Cetirizine, (±)-[2-[4-[(4-chlorophenyl)phenylmethyl]- 1-piperazinyl]ethoxy]acetic acid (Zyrtec), is a racemic compound available as a white crystalline powder that is water soluble. Cetirizine is the primary acid metabolite of hydroxyzine, resulting from complete oxidation of the primary alcohol moiety. This compound is zwitterionic and relatively polar and thus does not penetrate or accumulate in the CNS. Before its introduction in the United States, cetirizine was one of the most widely prescribed H1-antihistamines in Europe.Cetirizine is indicated for the temporary relief of runny nose, sneezing, itching of the nose or throat, and/or itchy, watery eyes caused by hay fever or other upper respiratory allergies. It also relieves itching caused by hives (urticaria), but it will not prevent hives or an allergic skin reaction from occurring.
Clinical Use
Cetirizine, the acid metabolite from oxidation of the primary alcohol of the antihistamine hydroxyzine, is a widely used antihistamine. It has a long duration of action and is highly selective for H1 receptors. No cardiotoxicity has been reported, but some drowsiness occurs.Cetirizine 준비 용품 및 원자재
원자재
에톡시아세트산
Piperazine, 1-[(4-chlorophenyl)phenylmethyl]-4-[2-(2,2-diethoxyethoxy)ethyl]-
히드록시진 수화염화물
Cetirizine dihydrochloride
2-[2-[4-[(4-chlorophenyl)phenylmethyl]piperazin-1-yl]ethoxy]ethanol hydrochloride
4-[(4-CHLOROPHENYL)PHENYLMETHYL]-1-PIPERAZINEETHANOL DIHYDROCHLORIDE
탄소
소듐 클로로아세테이트
클로로아세트산
준비 용품
Cetirizine 공급 업체
글로벌( 207)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 |
sales@hbmojin.com | China | 12456 | 58 |
| Hebei Yanxi Chemical Co., Ltd. | +8617531190177 |
peter@yan-xi.com | China | 5993 | 58 |
| Chengdu Aupone Pharmaceutical Co.Ltd. | +86-28-+86-28-87843998-6060-6060 +8618631098571 |
lijiaqi@aupone.com | China | 43 | 58 |
| Shaanxi TNJONE Pharmaceutical Co., Ltd | +8618740459177 |
sarah@tnjone.com | China | 958 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21691 | 55 |
| Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 |
product@chemlin.com.cn | CHINA | 3012 | 60 |
| Hebei Guanlang Biotechnology Co., Ltd. | +86-19930503282 |
alice@crovellbio.com | China | 8823 | 58 |
| Shenzhen Excellent Biotech Co., Ltd. | 13480692018 |
ramyan@ex-biotech.com | CHINA | 954 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 |
sales@conier.com | China | 49390 | 58 |
| career henan chemical co | +86-0371-86658258 15093356674; |
factory@coreychem.com | China | 29826 | 58 |
Cetirizine 관련 검색:
메틸 페닐 실로산과 실리콘 메틸파라벤 2,2-다이메틸프로판산 트리페닐주석 아세트산 초산 디메틸벤질카비닐 N-메틸피페라진 에톡시아세트산
acetic acid, triethoxy-, ethyl ester
Methyl 2,2-dimethylphenylacetate
Chlorodimethylphenylsilane
Loratadine
Ebastine
Levoceitrizine Hcl
Cetirizine-d4
Cetirizine dihydrochloride
CETIRIZINE DIHYDROCHLORIDE MM(CRM STANDARD),CETIRIZINE DIHYDROCHLORIDE EPC(CRM STANDARD)
Levocetirizine dihydrochloride
CETIRIZINE N-OXIDE