트리메타디온
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트리메타디온 속성
- 녹는점
- 45-46°C
- 끓는 점
- 78-80°C 5mm
- 밀도
- 1.3075 (rough estimate)
- 굴절률
- 1.4290 (estimate)
- 인화점
- 78-80°C/5mm
- 저장 조건
- Inert atmosphere,Room Temperature
- 용해도
- 물에 용해되며 에탄올에 매우 용해됩니다(96%).
- 산도 계수 (pKa)
- -2.18±0.40(Predicted)
- 색상
- 흰색에서 황백색까지
- 수용성
- 물 50g/L에 용해됩니다.
- Merck
- 14,9706
- BRN
- 121627
- CAS 데이터베이스
- 127-48-0(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 위험품 표기 | T | ||
|---|---|---|---|
| 위험 카페고리 넘버 | 61-20/21/22 | ||
| 안전지침서 | 53-22-36/37/39-45 | ||
| WGK 독일 | 3 | ||
| RTECS 번호 | RQ2100000 |
트리메타디온 C화학적 특성, 용도, 생산
화학적 성질
White, granular, crystalline substance; camphor-like odor. Soluble in water; freely soluble in alcohol, chloroform, and ether; pH 6.0 (5% solution).용도
3,5,5-Trimethyloxazolidine-2,4-dione is used in the control of absence (petit mal) seizures that are refractory to treatment with other medications. It is used in the treatment of epilepsy.위험도
May have adverse side effects; toxic in overdose.Clinical Use
Trimethadione is indicated only for control of absence seizures refractory to treatment with other AEDs. It is ineffective against other seizure types. Trimethadione is a pro-drug and is metabolized by N-demethylation to dimethadione, which is effective in the pentylenetetrazole test, which acts by decreasing T-type calcium currents. Trimethadione is rapidly absorbed, is not protein bound, and has a half-life of 16 to 24 hours. The half-life of dimethadione, however, is substantially longer (i.e., 6–13 days), and dimethadione accumulates to concentrations greater than the parent drug. Because of its potentially fatal side effects. including aplastic anemia, nephrosis, idiosyncratic rashes, and exfoliative dermatitis, trimethadione rarely is used today.트리메타디온 준비 용품 및 원자재
원자재
요오드 메탄
요소
나트륨
에틸알코올
폴리우레탄 중합체
2(5H)-Oxazolone, 4-methoxy-5,5-dimethyl-
5,5-Dimethyl-2-thioxooxazolidin-4-one
2,4-Oxazolidinedione, 3,5-dimethyl-
Ethyl 2-hydroxyisobutyrate
다이메타다이온
디에틸에테르
메틸 이소시아네이트
이산화탄소
디메틸설페이트
준비 용품
트리메타디온 공급 업체
글로벌( 96)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 |
marketing@targetmol.com | United States | 19892 | 58 |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 |
sales@hzclap.com | CHINA | 6313 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 |
1026@dideu.com | China | 29220 | 58 |
| Alfa Chemistry | +1-5166625404 |
Info@alfa-chemistry.com | United States | 21317 | 58 |
| Nantong HI-FUTURE Biology Co., Ltd. | +undefined18051384581 |
sales@chemhifuture.com | China | 3136 | 58 |
| Aladdin Scientific | +1-833-552-7181 |
sales@aladdinsci.com | United States | 57511 | 58 |
| Mainchem Co., Ltd. | +86-0592-6210733 |
sale@mainchem.com | China | 32360 | 55 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006608290; 18621169109 |
market03@meryer.com | China | 40241 | 62 |
| Alfa Aesar | 400-6106006 |
saleschina@alfa-asia.com | China | 30132 | 84 |
| Energy Chemical | 021-021-58432009 400-005-6266 |
sales8178@energy-chemical.com | China | 44751 | 61 |
트리메타디온 관련 검색:
3-(3,5-다이클로로페닐)-5-에텐일-5-메틸-2,4-옥사졸리딘다이온 트리메타디온
Triazophos
Metribuzin
carfentrazone-ethyl
Sodium 2-propylpentanoate
LACOSAMIDE
Gabapentin
PARAMETHADIONE (500 MG)
3-ethyl-5,5-dimethyloxazolidine-2,4-dione
Docetaxel Metabolite M4
Dichlozolinate
Dichlozoline
vinzolidine
2,4-Oxazolidinedione, 3-(3,5-dichlorophenyl)-5-methyl-5-oxiranyl-
3-(2-AMINO-ETHYL)-1-OXA-3-AZA-SPIRO[4.4]NONANE-2,4-DIONE HYDROCHLORIDE
3-(2-AMINO-ETHYL)-5,5-DIMETHYL-OXAZOLIDINE-2,4-DIONE HYDROCHLORIDE
HOY-DIMETHADIONE-2-14C