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1,1,1,2,3,3,3-헵타플루오로프로판

1,1,1,2,3,3,3-헵타플루오로프로판
1,1,1,2,3,3,3-헵타플루오로프로판 구조식 이미지
카스 번호:
431-89-0
한글명:
1,1,1,2,3,3,3-헵타플루오로프로판
동의어(한글):
1,1,1,2,3,3,3-헵타플루오로프로페인;1,1,1,2,3,3,3-헵타플루오로프로판;하이드로플루오로카본227이에이
상품명:
1,1,1,2,3,3,3-Heptafluoropropane
동의어(영문):
hfc-227ea;R227ea;R227;HFC-227;HEPTAFLUOROPROPANE;FM-200;Apaflurane;2-hydroheptafluoropropane;Propane, 1,1,1,2,3,3,3-heptafluoro-;R 227ea
CBNumber:
CB4692270
분자식:
C3HF7
포뮬러 무게:
170.03
MOL 파일:
431-89-0.mol

1,1,1,2,3,3,3-헵타플루오로프로판 속성

녹는점
-126.8°C
끓는 점
-16.4°C
밀도
1,409 g/cm3
굴절률
1.2747 (estimate)
용해도
Soluble 1 in 1725 parts of water at 20°C.
안정성
Stable. Incompatible with strong oxidizing agents, alkali metals
CAS 데이터베이스
431-89-0(CAS DataBase Reference)
NIST
1,1,1,2,3,3,3-Heptafluoropropane(431-89-0)
EPA
HFC-227ea (431-89-0)
안전
  • 위험 및 안전 성명
위험품 표기 Xi
안전지침서 23-38
유엔번호(UN No.) 3296
위험 참고 사항 Irritant
위험 등급 2.2
유해 물질 데이터 431-89-0(Hazardous Substances Data)
기존화학 물질 97-3-48
그림문자(GHS):
신호 어:
유해·위험 문구:
암호 유해·위험 문구 위험 등급 범주 신호 어 그림 문자 P- 코드
예방조치문구:
NFPA 704
0
1 1

1,1,1,2,3,3,3-헵타플루오로프로판 MSDS


1,1,1,2,3,3,3-Heptafluoropropane

1,1,1,2,3,3,3-헵타플루오로프로판 C화학적 특성, 용도, 생산

화학적 성질

Heptafluoropropane is a liquefied gas and exists as a liquid at room temperature when contained under its own vapor pressure, or as a gas when exposed to room temperature and atmospheric pressure. The liquid is practically odorless and colorless. The gas in high concentration has a faint etherlike odor. Heptafluoropropane is noncorrosive, nonirritating, and nonflammable.

용도

HFC 227ea is being developed as a CFC replacement in refrigerants, high temperature heat pumps, air-conditioning systems; as a fire suppressant; and for pharmaceutical aerosols and metered-dose inhalers.

Pharmaceutical Applications

Heptafluoropropane is classified as a hydrofluorocarbon (HFC) aerosol propellant since the molecule consists only of carbon, fluorine, and hydrogen atoms. It does not contain any chlorine and consequently does not affect the ozone layer, nor does it have an effect upon global warming. It is therefore considered as an alternative propellant to CFCs for metered-dose inhalers (MDIs). While some of its physical and chemical properties are known, little has been published in regard to its use as a replacement for CFCs in MDIs.
The vapor pressure of heptafluoropropane is somewhat lower than that of tetrafluoroethane and dichlorodifluoromethane but considerably higher than the vapor pressure used to formulate most MDIs.
When heptafluoropropane is used for pharmaceutical aerosols and MDIs, the pharmaceutical grade must be specified. Industrial grades may not be suitable due to their impurity profile. Similarly to tetrafluoroethane, heptafluoropropane is not a good solvent for medicinal agents or for the commonly used surfactants and dispersing agents used in the formulation of MDIs.
There are several MDIs formulated with this propellant worldwide that contain a steroid as the active ingredient.

Safety

Heptafluoropropane is used as a fire extinguisher and is applicable as a non-CFC propellant in various metered-dose inhalers. Heptafluoropropane is regarded as nontoxic and nonirritating when used as directed. No acute or chronic hazard is present when it is used normally. Inhaling high concentrations of heptafluoropropane vapors can be harmful and is similar to inhaling vapors of other propellants. Deliberate inhalation of vapors of heptafluoropropane can be dangerous and may cause death. The same labeling required of CFC aerosols would be required for those containing heptafluoropropane as a propellant (except for the EPA requirement).

저장

Heptafluoropropane is a nonreactive and stable material. The liquefied gas is stable when used as a propellant and should be stored in a metal cylinder in a cool, dry place.

1,1,1,2,3,3,3-헵타플루오로프로판 준비 용품 및 원자재

원자재

준비 용품


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