ChemicalBook >제품 카탈로그 >GSK-3β Inhibitor XVIII

GSK-3β Inhibitor XVIII

GSK-3β Inhibitor XVIII 구조식 이미지

카스 번호:: 1139875-74-3

상품명:: GSK-3β Inhibitor XVIII

동의어(영문):: GSK3β-IN-1a;GSK3β-IN-1a;GSK3β Inhibitor XVIII;GSK-3β Inhibitor XVIII;GSK-3β Inhibitor XVIII - CAS 1139875-74-3 - Calbiochem;2-chloro-4-[[4-(2-thienyl)-2-pyrimidinyl]amino]phenyl](4-methyl-1-piperazinyl)-,methanone;Methanone, [2-chloro-4-[[4-(2-thienyl)-2-pyrimidinyl]amino]phenyl](4-methyl-1-piperazinyl)-

CBNumber:: CB52602508

분자식:: C20H20ClN5OS

포뮬러 무게:: 413.92

MOL 파일:: 1139875-74-3.mol

속성

안전

용도

공급 업체 15

GSK-3β Inhibitor XVIII 속성

끓는 점: 632.3±65.0 °C(Predicted)

밀도: 1.358±0.06 g/cm3(Predicted)

저장 조건: +2C to +8C

용해도: DMSO: 용해될 수 있다

산도 계수 (pKa): 6?+-.0.10(Predicted)

물리적 상태: 흰색 고체

안전

GSK-3β Inhibitor XVIII C화학적 특성, 용도, 생산

개요

GSK3β inhibitor XVIII is an inhibitor of glycogen synthase kinase 3β (GSK3β; IC₅₀ = 64 nM). It induces expression of a luciferase reporter in HEK293 cells expressing wild-type Wnt (EC₅₀ = ~1.25 μM) but not in cells expressing a β-catenin/TCF binding site-mutant Wnt. GSK3β inhibitor XVIII increases β-catenin accumulation in the nucleus of HEK293 cells. It induces proliferation of R7T1 β-cells (EC₅₀ = 1,143 nM), an effect that can be blocked by the COX and Wnt signaling inhibitor sulindac , and rat primary β-cells.

GSK-3β Inhibitor XVIII 준비 용품 및 원자재

원자재

준비 용품

GSK-3β Inhibitor XVIII 공급 업체

글로벌( 15)공급 업체

공급자	전화	이메일	국가	제품 수	이점
HANGZHOU CLAP TECHNOLOGY CO.,LTD	86-571-88216897,88216896 13588875226	sales@hzclap.com	CHINA	6313	58
BOC Sciences	16314854226	info@bocsci.com	United States	9926	65
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	info@efebio.com	China	9709	58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	18818260767	sales@chemegen.com	China	11289	58
TargetMol Chemicals Inc.	4008200310	marketing@tsbiochem.com	China	24131	58
Nanjing Tengyi Biotechnology Co., Ltd	025-58851786 17714337195	sales@tybiochem.com	China	4257	58
Nantong Hanfang Biotechnology Co. , Ltd.	3674309880	hanfangpharma@126.com	China	30968	58
Nanjing Shizhou Biology Technology Co.,Ltd	025-85560043 15850508050	cindy.huang@synzest.com	China	12007	58

GSK-3β Inhibitor XVIII 관련 검색:

2-[(6-Amino-9H-purin-9-yl)methyl]-5-methyl-3-(2-methylphenyl)-4(3H)-quinazolinone N-[4-[5-(1,3-BENZODIOXOL-5-YL)-3-METHOXY-1H-1,2,4-TRIAZOL-1-YL]PHENYL]-2-(PHENYLTHIO)ACETAMIDE NSC 23766 TETRAHYDROCHLORIDE NSC697923 MIF Antagonist, ISO-1 Pictilisib JNJ-10198409 Chk2 Inhibitor Trolox C2 CERAMIDE Motesanib PD 173074 Compound 28 Glycogen Phosphorylase Inhibitor MMP-9 INHIBITOR I Compound 23 ERK Inhibitor 6-HYDROXY-2,5,7,8-TETRAMETHYLCHROMAN-2-CARBOXYLIC ACID