눈에 묻으면 몇 분간 물로 조심해서 씻으시오. 가능하면 콘택트렌즈를 제거하시오. 계속 씻으시오.
NFPA 704
0
2
0
3-(azepan-1-ylsulfonyl)-N-(3-broMophenyl)benzaMide C화학적 특성, 용도, 생산
개요
The sirtuin SIRT2 is a deacetylase which targets α-tubulin, histone 4, forkhead transcription factors, and several other substrates. It has roles in metabolic diseases, cancer, age-related disorders, and neurodegenerative diseases, potentially including Alzheimer’s, Huntington’s, and Parkinson’s diseases. AK-7 is a cell- and brain-permeable inhibitor of SIRT2 (IC50 = 15.5 μM). In culture, it diminishes neuronal cell death induced by mutant huntingtin fragment. In addition, AK-7 down-regulates cholesterol biosynthetic gene expression and reduces total cholesterol levels in neurons in vivo.
3-(azepan-1-ylsulfonyl)-N-(3-broMophenyl)benzaMide 준비 용품 및 원자재
원자재
준비 용품
3-(azepan-1-ylsulfonyl)-N-(3-broMophenyl)benzaMide 공급 업체
