트리에틸시트레이트
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트리에틸시트레이트 속성
- 녹는점
- -55 °C
- 끓는 점
- 235 °C/150 mmHg (lit.)
- 밀도
- 1.14 g/mL at 25 °C (lit.)
- 증기 밀도
- 9.7 (vs air)
- 증기압
- 1 mm Hg ( 107 °C)
- 굴절률
- n
20/D 1.442(lit.)
- 인화점
- >230 °F
- 저장 조건
- Store below +30°C.
- 용해도
- H2O: 용해성
- 산도 계수 (pKa)
- 11.57±0.29(Predicted)
- 물리적 상태
- 액체
- 색상
- 투명한
- 냄새
- 냄새 없는
- 수용성
- 5.7g/100mL(25℃)
- 어는점
- -55℃
- Merck
- 14,2326
- JECFA Number
- 629
- BRN
- 1801199
- InChIKey
- DOOTYTYQINUNNV-UHFFFAOYSA-N
- LogP
- 1.267 (est)
- CAS 데이터베이스
- 77-93-0(CAS DataBase Reference)
안전
- 위험 및 안전 성명
| 위험품 표기 | Xn | ||
|---|---|---|---|
| 위험 카페고리 넘버 | 20 | ||
| 안전지침서 | 24/25-45 | ||
| WGK 독일 | 1 | ||
| RTECS 번호 | GE8050000 | ||
| TSCA | Yes | ||
| HS 번호 | 2918 15 00 | ||
| 유해 물질 데이터 | 77-93-0(Hazardous Substances Data) | ||
| 독성 | LD50 orally in Rabbit: > 3200 mg/kg LD50 dermal Rabbit > 5000 mg/kg | ||
| 기존화학 물질 | KE-20840 |
트리에틸시트레이트 C화학적 특성, 용도, 생산
화학적 성질
Triethyl citrate is a clear, viscous, odorless, and practically colorless, hygroscopic liquid.출처
Reported found in Morello cherry, sour cherry and red currant. Also reported found in raw cabbage and white wine.용도
Triethyl Citrate is a sequestrant that is an oily liquid, slightly solu- ble in water. it is found in lemon drinks.제조 방법
By esterification of ethyl alcohol with citric acid.생산 방법
Triethyl citrate is prepared by the esterification of citric acid and ethanol in the presence of a catalyst.일반 설명
Triethyl citrate is a safe direct food additive.Pharmaceutical Applications
Triethyl citrate and the related esters acetyltriethyl citrate, tributyl citrate, and acetyltributyl citrate are used to plasticize polymers in formulated pharmaceutical coatings. The coating applications include capsules, tablets, beads, and granules for taste masking, immediate release, sustained-release, and enteric formulations.Triethyl citrate is also used as a direct food additive for flavoring, for solvency, and as a surface active agent.
Safety Profile
Moderately toxic by intraperitoneal route. Mildly toxic by ingestion and inhalation. Combustible liquid when exposed to heat or flame. To fight fire, use dry chemical, CO2. When heated to decomposition it emits acrid smoke and irritating fumes. See also ESTERS and CITRIC ACID.Safety
Triethyl citrate is used in oral pharmaceutical formulations and as a direct food additive. It is generally regarded as a nontoxic and nonirritant material. However, ingestion of large quantities may be harmful.LD50 (mouse, IP): 1.75 g/kg
LD50 (rat, IP): 4 g/kg
LD50 (rat, oral): 5.9 g/kg
LD50 (rat, SC): 6.6 g/kg
저장
Triethyl citrate should be stored in a closed container in a cool, dry location. When stored in accordance with these conditions, triethyl citrate is a stable product.비 호환성
Triethyl citrate is incompatible with strong alkalis and oxidizing materials.Regulatory Status
GRAS listed. Accepted for use as a food additive in Europe. Included in the FDA Inactive Ingredients Database (oral capsules and tablets). Included in the Canadian List of Acceptable Nonmedicinal Ingredients.트리에틸시트레이트 준비 용품 및 원자재
원자재
준비 용품
트리에틸시트레이트 공급 업체
글로벌( 588)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Jiangxi Alpha Hi-tech Pharmaceutical Co., Ltd | 510-85010237 |
overseamarketing@alphahi-tech.com | CHINA | 41 | 58 |
| Weifang Wehibest Supply Chain Co.,Ltd | +8613583620690 |
hotspotbiotech@163.com | China | 926 | 58 |
| Hebei Yime New Material Technology Co., Ltd. | +86-66697723 +86-17703311139 |
admin@china-yime.com | China | 563 | 58 |
| Henan Bao Enluo International TradeCo.，LTD | +86-17331933971 +86-17331933971 |
deasea125996@gmail.com | China | 2503 | 58 |
| Hebei Jingbo New Material Technology Co., Ltd | +8619931165850 |
hbjbtech@163.com | China | 1000 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 |
info@fdachem.com | China | 7845 | 58 |
| Hebei Saisier Technology Co., LTD | +86-18400010335 +86-13102810335 |
admin@hbsaisier.cn | China | 747 | 58 |
| Shaanxi TNJONE Pharmaceutical Co., Ltd | +8618740459177 |
sarah@tnjone.com | China | 893 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21691 | 55 |
| Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 |
fandachem@gmail.com | China | 9348 | 55 |