2-Amino-4,6-dihydroxypyrimidine
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2-Amino-4,6-dihydroxypyrimidine 속성
- 녹는점
- >300 °C (lit.)
- 끓는 점
- 235.85°C (rough estimate)
- 밀도
- 1.4748 (rough estimate)
- 굴절률
- 1.5000 (estimate)
- 저장 조건
- Keep in dark place,Inert atmosphere,2-8°C
- 용해도
- 수성 알칼리에 용해됩니다.
- 산도 계수 (pKa)
- 7.45±0.10(Predicted)
- 물리적 상태
- 가루
- 색상
- 황백색에서 연한 분홍색 또는 연한 노란색
- BRN
- 510297
- InChIKey
- AUFJTVGCSJNQIF-UHFFFAOYSA-N
- CAS 데이터베이스
- 56-09-7(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 위험품 표기 | Xn | ||
|---|---|---|---|
| 위험 카페고리 넘버 | 20/21/22-36/37/38 | ||
| 안전지침서 | 24/25-36-26 | ||
| WGK 독일 | 1 | ||
| RTECS 번호 | UW7361000 | ||
| TSCA | Yes | ||
| HS 번호 | 29339900 |
2-Amino-4,6-dihydroxypyrimidine C화학적 특성, 용도, 생산
개요
2-Amino-4,6-dihydroxypyrimidine is a hydroxypyrimidine.화학적 성질
White Solid용도
2-Amino-4,6-dihydroxypyrimidine acts as an intermediate in the production of antimicrobial guanylsulfonamides. It also acts as an intermediate in pharmaceuticals and agrochemicals.Synthesis
The synthesis of 2-Amino-4,6-dihydroxypyrimidine is as follows:A freshly-prepared sodiummethoxide solution in methanol (25 ml) was added to a round-bottomed flask containing guanidine hydrochloride(15 mmol), stirred for a few minutes, before dimethyl malonate (15 mmol)was slowly added. The mixture was heated under reflux for about 2-3hours. After evaporation of the solvent under reduced pressure, the resultingwhite solid was dissolved in a minimum amount of water and the pH adjusted to 6with 10% HCl. The precipitate obtained was filtered and washed with distilledwater and ethanol, respectively, to obtain pure 2-amino-4,6-pyrimidinediol.(Note: sodium methoxide solution was prepared by addition of small pieces ofsodium metal in methanol).Yield: 85%;solid, m.p. 195-197 °C.
2-Amino-4,6-dihydroxypyrimidine 준비 용품 및 원자재
원자재
준비 용품
2-Amino-4,6-dihydroxypyrimidine 공급 업체
글로벌( 372)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Nanjing Triumpharm Co.,Ltd | +86-02586182925 +86-15105172550 |
info@triumpharm.com | China | 129 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29797 | 60 |
| career henan chemical co | +86-0371-86658258 |
sales@coreychem.com | China | 29914 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 |
linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Xi'an Kono chem co., Ltd., | 029-86107037 13289246953 |
info@konochemical.com | China | 2995 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 |
linda@hubeijusheng.com | CHINA | 22968 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 |
sales@chemdad.com | China | 39916 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 |
sales@alchempharmtech.com | United States | 63711 | 58 |
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 |
sales@chemwish.com | CHINA | 10828 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 |
sales@conier.com | China | 49390 | 58 |