2-Hydroxychalcone
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2-Hydroxychalcone 속성
- 녹는점
- 144-150 °C(lit.)
- 끓는 점
- 396.3±34.0 °C(Predicted)
- 밀도
- 1.191±0.06 g/cm3(Predicted)
- 산도 계수 (pKa)
- 9.26±0.35(Predicted)
- 물리적 상태
- 가루
- 색상
- 노란색
- BRN
- 2049134
- CAS 데이터베이스
- 644-78-0(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
2-Hydroxychalcone C화학적 특성, 용도, 생산
개요
2-hydroxychalcone, a natural flavonoid, is a potent antioxidant, inhibiting lipid peroxidation. It is also capable of inducing apoptosis by downregulating Bcl-2 levels and inhibiting the activation of NF-kB.in vitro
2-Hydroxychalcone inhibits invasion of triple negative breast cancer cells.2-hydroxychalcone inhibits the adhesion of peripheral neutrophils to the endothelial cell monolayers by inhibiting the expression of ICAM-1, VCAM-1, and E-selectin in a concentration-dependent manner.
참고 문헌
[1]. Sun Young Kim, et al. 2-Hydroxychalcone and Xanthohumol Inhibit Invasion of Triple Negative Breast Cancer Cells. Chem Biol Interact. 2013 May 25;203(3):565-72. DOI:10.1016/j.cbi.2013.03.012[2]. B Madan, et al. 2'-hydroxychalcone Inhibits Nuclear factor-kappaB and Blocks Tumor Necrosis Factor-Alpha- And Lipopolysaccharide-Induced Adhesion of Neutrophils to Human Umbilical Vein Endothelial Cells. Mol Pharmacol. 2000 Sep;58(3):526-34. DOI:10.1124/MOL.58.3.526
[3]. Sonochemical Synthesis of 2’-Hydroxy-Chalcone Derivatives with Potential Anti-Oomycete Activity doi: 10.3390/antibiotics9090576
2-Hydroxychalcone 준비 용품 및 원자재
원자재
준비 용품
2-Hydroxychalcone 공급 업체
글로벌( 95)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 |
zheyansh@163.com | CHINA | 3620 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 |
linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 15093356674; |
laboratory@coreychem.com | China | 30255 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418671 |
sales@tnjchem.com | China | 34572 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 |
info@dycnchem.com | CHINA | 52867 | 58 |
| sgtlifesciences pvt ltd | +8617013299288 |
dj@sgtlifesciences.com | China | 12382 | 58 |
| GLR Innovations | +91 9891111994 |
info@glrgroup.in | India | 4542 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 |
support@targetmol.com | United States | 19973 | 58 |
| GIHI CHEMICALS CO.,LIMITED | +8618058761490 |
info@gihichemicals.com | China | 49999 | 58 |
| Aladdin Scientific | +1-833-552-7181 |
sales@aladdinsci.com | United States | 57511 | 58 |
2-Hydroxychalcone 관련 검색:
2-히드록시캘콘
HYDROXYCHALCONE, 4-,4-HYDROXYCHALCONE
2'-Hydroxychalcone
DIMETHOXY-2'-HYDROXYCHALCONE, 2,3-,2,3-DIMETHOXY-2'-HYDROXYCHALCONE
4'-HYDROXYCHALCONE,HYDROXYCHALCONE, 4'-
trans-Chalcone
5'-CHLORO-3,4-DIMETHOXY-2'-HYDROXYCHALCONE
4',6'-DIMETHOXY-2'-HYDROXYCHALCONE,DIMETHOXY-2'-HYDROXYCHALCONE, 4',6'-
4',6'-DIMETHOXY-4-FLUORO-2'-HYDROXYCHALCONE
(E)-2'-hydroxychalcone
5'-BROMO-4-CHLORO-2'-HYDROXYCHALCONE
5'-BROMO-3,4-DIMETHOXY-2'-HYDROXYCHALCONE
4-BUTYL-4'-HYDROXYCHALCONE
4'-FLUORO-2-HYDROXYCHALCONE
4-CHLORO-5'-FLUORO-2'-HYDROXYCHALCONE
4-CHLORO-2'-HYDROXYCHALCONE
4-CHLORO-4',6'-DIMETHOXY-2'-HYDROXYCHALCONE
4',6'-DIMETHOXY-4-DIMETHYLAMINO-2'-HYDROXYCHALCONE