1-EBIO
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1-EBIO 속성
- 녹는점
- 118-120 °C(Solv: ethyl acetate (141-78-6))
- 밀도
- 1.161±0.06 g/cm3(Predicted)
- 저장 조건
- Sealed in dry,Room Temperature
- 용해도
- DMSO: ≥20mg/mL
- 물리적 상태
- 가루
- 산도 계수 (pKa)
- 12.29±0.30(Predicted)
- 색상
- 수정 같은
- 안정성
- 제공된 대로 구매일로부터 1년 동안 안정적입니다. DMSO 또는 에탄올 용액은 -20°C에서 최대 3개월 동안 보관할 수 있습니다.
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
1-EBIO C화학적 특성, 용도, 생산
개요
1-EBIO is an activator of Ca2+-sensitive K+ channels (EC50 = 490 μM in T84 human carcinoma cells).This action is sensitive to the neurotoxin charybdotoxin (Ki = 3.5 nM). In mouse colonic epithelia, 1-EBIO also activates cAMP-sensitive K+ channels, a response this is inhibited by 293B.In this type of epithelium, but not mouse nasal epithelia, 1-EBIO activates both types of channels, resulting in large Cl- secretory currents.It also activates the human intermediate conductance Ca2+-activated K+ channel (EC50 = 74 μM).1-EBIO is currently used to study the role of these types of K+ channels in diverse physiological functions.용도
1-EBIO stimulates Cl- secretion in secretory epithelia through direct activation of clacium potassium channels.1-EBIO was used to study the electrical activity modulated by Ca+2-activated K+ channels in rat central neurons. The effect of 1-EBIO on human intermediate conductance channels was studied.
The K+ channel opener 1-EBIO potentiates residual function of mutant CFTR in rectal biopsies from cystic fibrosis patients
생물학적 활성
Activator of epithelial K Ca channels, stimulates a large and sustained trans-epithelial Cl - secretory response across T84 monolayers. Induces hyperpolarization to the same magnitude as ACh in aortic value endothelial cells.1-EBIO 준비 용품 및 원자재
원자재
1-(1-phenyl-vinyl)-1,3-dihydro-benzoimidazol-2-one
2H-Benzimidazol-2-one, 1-ethyl-3-(1E)-1-hexen-1-yl-1,3-dihydro-
N-에틸벤젠-1,2-디아민
N-ETHYL-2-NITROANILINE
2H-Benzimidazole-2-thione,1-ethyl-1,3-dihydro-(9CI)
1,1′-카보닐디이미다졸
O-페닐렌다이아민
준비 용품
1-EBIO 공급 업체
글로벌( 109)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
Alchem Pharmtech,Inc. | 8485655694 |
sales@alchempharmtech.com | United States | 63711 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 |
marketing@targetmol.com | United States | 19892 | 58 |
Alfa Chemistry | |
Info@alfa-chemistry.com | United States | 24072 | 58 |
Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 |
sales@molcore.com | China | 49739 | 58 |
Aladdin Scientific | +1-+1(833)-552-7181 |
sales@aladdinsci.com | United States | 57511 | 58 |
Amadis Chemical Company Limited | 571-89925085 |
sales@amadischem.com | China | 131980 | 58 |
J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 |
jkinfo@jkchemical.com | China | 96815 | 76 |
3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 |
3bsc@sina.com | China | 15848 | 69 |
Ascent Scientific | 4401179829988 |
customerservice@ascentscientific.co.uk | United Kingdom | 279 | 60 |
Artis Chemistry (Shanghai) Co. Ltd. | 86-21-60936353 |
China | 336 | 58 |
1-EBIO 관련 검색:
4-(2-케토-1-벤지미다졸린일)피페리딘 드로페리돌, 펜타닐
1-ISOPROPENYL-2-BENZIMIDAZOLIDINONE
Pimozide
1-(3-Chloropropyl)-1,3-dihydro-2H-benzimidazol-2-one
Oxatomide
1,3-DIHYDRO-1-(1,2,3,6-TETRAHYDRO-4-PYRIDINYL)-2H-BENZIMIDAZOLE-2-ONE
Domperidone
1-EBIO
1H-Benzimidazole-1-propanoic acid, 2,3-dihydro-2-oxo-
SALOR-INT L202436-1EA
ETHYL 3-(2,6-DICHLOROBENZYL)-2-OXO-2,3-DIHYDRO-1H-1,3-BENZIMIDAZOLE-1-CARBOXYLATE
ETHYL 3-(2-METHYLBENZYL)-2-OXO-2,3-DIHYDRO-1H-1,3-BENZIMIDAZOLE-1-CARBOXYLATE
ETHYL 3-(4-METHYLBENZYL)-2-OXO-2,3-DIHYDRO-1H-1,3-BENZIMIDAZOLE-1-CARBOXYLATE
ETHYL 3-(3,4-DICHLOROBENZYL)-2-OXO-2,3-DIHYDRO-1H-1,3-BENZIMIDAZOLE-1-CARBOXYLATE
ETHYL 3-(3-METHYLBENZYL)-2-OXO-2,3-DIHYDRO-1H-1,3-BENZIMIDAZOLE-1-CARBOXYLATE
3-BENZYL-2-OXO-2,3-DIHYDRO-BENZOIMIDAZOLE-1-CARBOXYLIC ACID ETHYL ESTER
ETHYL 3-(2,4-DICHLOROBENZYL)-2-OXO-2,3-DIHYDRO-1H-1,3-BENZIMIDAZOLE-1-CARBOXYLATE