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Cefmenoxime

Cefmenoxime 구조식 이미지

카스 번호:: 65085-01-0

상품명:: Cefmenoxime

동의어(영문):: CMX;SCE 1365;AB 50912;CEFMENOXIME;Cefotaxime Isomer;Cefmenoxime USP/EP/BP;7β-[[(Z)-(2-Amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-[[(1-methyl-1H-tetrazole-5-yl)thio]methyl]cepham-3-ene-4-carboxylic acid;(6R,7R)-7-[[(Z)-(2-Aminothiazol-4-yl)(methoxyimino)acetyl]amino]-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;(6R,7R)-7α-[2-(2-Amino-4-thiazolyl)-2-[(Z)-methoxyimino]acetylamino]-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;[6R-[6α，7β(Z)]]-7-[[(2-Amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-[[(1-methyl-1H-tetrazol-5-y1)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oet-2-ene-2-carboxylic acid

CBNumber:: CB7771510

분자식:: C16H17N9O5S3

포뮬러 무게:: 511.56

MOL 파일:: 65085-01-0.mol

속성

안전

용도

공급 업체 88

Cefmenoxime 속성

밀도: 1.96±0.1 g/cm3(Predicted)

산도 계수 (pKa): 2.61±0.50(Predicted)

CAS 데이터베이스: 65085-01-0(CAS DataBase Reference)

안전

Cefmenoxime C화학적 특성, 용도, 생산

용도

Cefmenoxime (cas# 65085-01-0) is a compound useful in organic synthesis.

정의

ChEBI: A third-generation cephalosporin antibiotic, bearing a 2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino group at the 7beta-position and a [(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl group at the 3-position.

Antimicrobial activity

A semisynthetic cephalosporin supplied as the hydrochloride. Its activity is very similar to that of cefotaxime. A 500 mg intramuscular injection achieves a plasma concentration of 15 mg/L after 40 min. A concentration of 200 mg/L is attained after intravenous administration of 1 g. The plasma half-life is c. 1 h. Around 77% is protein bound. Probenecid increases peak plasma levels and extends the plasma half-life to 1.8 h. Therapeutic concentrations are achieved in CSF. There is a degradation product with a long half-life (around 40 h), but 80–92% of the drug is recovered unchanged from the urine. In patients with renal insufficiency, no significant relation was found between creatinine clearance and peak serum concentrations but there was a linear relationship with plasma half-life and total body clearance. About 10% of the dose appears in the feces, mostly extensively degraded, possibly by the fecal flora.
Toxicity, side effects and clinical use are those common to group 4 cephalosporins.

Cefmenoxime 준비 용품 및 원자재

원자재

Three B Lithium tert-butoxide Acetate 브롬화암모늄 1H-TETRAZOLE 질소 세포탁심 나트륨 트리플루오로아세트 산 브로모벤젠 Cefotaxime N,N-디메틸아세트아미드 5-머캅토-1-메틸테트라졸

준비 용품

Cefmenoxime 공급 업체

글로벌( 88)공급 업체

공급자	전화	이메일	국가	제품 수	이점
Hebei Mojin Biotechnology Co., Ltd	+8613288715578	sales@hbmojin.com	China	12456	58
Hebei Lingding Biotechnology Co., Ltd.	+86-18031140164 +86-19933155420	erin@hbldbiotech.com	China	878	58
Shanghai Yingrui Biopharma Co., Ltd.	+86-21-33585366 - 03@	sales03@shyrchem.com	CHINA	738	60
Hebei Guanlang Biotechnology Co., Ltd.	+86-19930503282	alice@crovellbio.com	China	8823	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49390	58
career henan chemical co	+86-0371-86658258 15093356674;	factory@coreychem.com	China	29826	58
Hebei Runbin Biotechnology Co. LTD	13180553332	2179877681@qq.com	CHINA	996	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
Hebei Henghe Import and Export Trading Co. LTD	+8618032935937 18032916000	demi@hbtycoon.com	CHINA	449	58
Shaanxi Dideu Medichem Co. Ltd	+86-029-89586680 +86-18192503167	1026@dideu.com	China	9320	58

Cefmenoxime 관련 검색:

2-아미노-알파-(메톡시이미노)-4-티아졸아세트 산 포스티아제이트 세프티족심 나트륨 5-메틸-1,3,4-티아디아졸-2-티올 세포탁심 나트륨 디벤조티아질 디설파이드 벤조티아졸 2-메틸-4-이소티아졸린-3-온 세파렉신 산소, 냉각된 액체 7-(5-amino-5-carboxyvaleramido)cephalosporanic acid PENICILLINASE Methylchloroisothiazolinone/methylisothiazolinone mixture (MCIT/MIT) 2-(2-Aminothiazol-4-yl)glyoxylic acid Cefotaxime Ceftizoxime 7-TMCA 2Cefmenoxime·Hydrochloride,CEFMENOXIME HCL,CEFMENOXIME HYDROCHLORIDE