벤조티아졸
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벤조티아졸 속성
- 녹는점
- 2 °C (lit.)
- 끓는 점
- 231 °C (lit.)
- 밀도
- 1.238 g/mL at 25 °C (lit.)
- 증기 밀도
- 4.66 (vs air)
- 증기압
- 34 mm Hg ( 131 °C)
- 굴절률
- n
20/D 1.642(lit.)
- FEMA
- 3256 | BENZOTHIAZOLE
- 인화점
- >230 °F
- 저장 조건
- Keep in dark place,Inert atmosphere,Room temperature
- 용해도
- 3g/L
- 물리적 상태
- 액체
- 산도 계수 (pKa)
- 0.85±0.10(Predicted)
- 색상
- 투명한 황갈색~갈색
- 냄새
- 퀴놀린 냄새, 약간의 물-졸 냄새
- ?? ??
- 유황의
- 폭발한계
- 0.9-8.2%(V)
- 생물학적 소스
- synthetic
- 수용성
- 약간 용해됨
- Merck
- 14,1107
- JECFA Number
- 1040
- BRN
- 109468
- 안정성
- 안정적 - 환경에 대한 지속성이 매우 높은 것으로 간주됩니다. 강한 산화제와 호환되지 않습니다. 연소 생성물: 질소 산화물, 일산화탄소, 이산화탄소, 황산화물.
- InChIKey
- IOJUPLGTWVMSFF-UHFFFAOYSA-N
- LogP
- 2.01
- CAS 데이터베이스
- 95-16-9(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 위험품 표기 | Xn,T,Xi | ||
|---|---|---|---|
| 위험 카페고리 넘버 | 22-20/21/22-36-25-24-20 | ||
| 안전지침서 | 23-26-36-36/37-45 | ||
| 유엔번호(UN No.) | 2810 | ||
| WGK 독일 | 2 | ||
| RTECS 번호 | DL0875000 | ||
| TSCA | Yes | ||
| 위험 등급 | 6.1 | ||
| 포장분류 | III | ||
| HS 번호 | 29342080 | ||
| 유해 물질 데이터 | 95-16-9(Hazardous Substances Data) | ||
| 독성 | LD50 i.v. in mice: 95±3 mg/kg (Domino) | ||
| 기존화학 물질 | KE-02722 |
벤조티아졸 C화학적 특성, 용도, 생산
개요
Benzothiazole and its derivative are recognized as the most important heterocyclic compounds. This series of compounds is of particular interests. It has various kinds of pharmacological properties and has been included in many kinds of natural products and pharmaceutical agents. The broad spectrum of pharmacological activity in individual benzothiazole derivative enables it to serve as unique and valuable scaffolds for experimental drug design. It is already known that benzothiazole and its derivative has various biological applications including anticancer, antimicrobial, anticonvulsant, antiviral, antidiabetic, antipsychotic, antiinflammatory, analgesic, fungicidal and diuretic. Its derivatives also have many applications in polymer chemistry, dyes, drugs, and silver photography as well as rubber industry.화학적 성질
Benzothiazole has a delicate, persistent, rose-like odor similar to that of quinoline.출처
Reported found in apricot, cooked asparagus, mozzarella cheese, skim milk powder, roasted beef, beer, malt whiskey, coconut meat, fresh mango, cooked broccoli and kelp.용도
Various benzothiazole-benzamides synthesized were evaluated for their analgesic and antidepressant activities.정의
ChEBI: An organic heterobicyclic compound that is a fusion product between benzene and thiazole. The parent of the class of benzothiazoles.제조 방법
By refluxing a mixture of zinc o-aminophenylsulfide and formic acid, followed by steam distillation of the alkalized reaction mixture; by heating formanilid or dimethylaniline with sulfur; by oxidation of 2-mercaptobenzothiazole or of the corresponding disulfide.일반 설명
Benzothiazole, a volatile sulfur-containing heterocyclic compound, is one of the key odorants of heated milk. It is also reported to occur as a flavor component of miso, coconut meat and cooked-beef.위험도
Highly toxic by ingestion.Safety Profile
Poison by ingestion,intraperitoneal, intravenous, and possibly other routes.When heated to decomposition it emits very toxic fumesof SOx, CN??, and NOx.참고 문헌
Gupta, Akhilesh, and S. Rawat. "Synthesis and cyclization of benzothiazole." J. of Current Pharmaceutical Research 3.1 (2010): 13-25.Keri, Rangappa S., et al. "A comprehensive review in current developments of benzothiazole-based molecules in medicinal chemistry." European journal of medicinal chemistry 89 (2015): 207-251.
Khokra, Sukhbir L., et al. "Common methods to synthesize benzothiazole derivatives and their medicinal significance: a review." International Journal of Pharmaceutical Sciences and Research 2.6 (2011): 1356.
벤조티아졸 준비 용품 및 원자재
원자재
준비 용품
벤조티아졸 공급 업체
글로벌( 471)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Jinan Qinmu Fine Chemical Co.,Ltd. | +8618660799346 |
sales@qinmuchem.com | China | 1009 | 58 |
| Hebei Longbang Technology Co., LTD | +86-18633929156 +86-18633929156 |
admin@hblongbang.com | China | 972 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +86-15531157085 +86-15531157085 |
abby@chuanghaibio.com | China | 8805 | 58 |
| Hebei Mujin Biotechnology Co.,Ltd | +86 13288715578 +8613288715578 |
sales@hbmojin.com | China | 12822 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 |
sales1@chuanghaibio.com | China | 5878 | 58 |
| Anhui Ruihan Technology Co., Ltd | +8617756083858 |
daisy@anhuiruihan.com | China | 973 | 58 |
| airuikechemical co., ltd. | +86-18353166132 +86-18353166132 |
sales02@airuikechemical.com | China | 983 | 58 |
| Hebei Saisier Technology Co., LTD | +86-18400010335 +86-18034520335 |
admin@hbsaisier.cn | China | 1015 | 58 |
| Hebei Zhuanglai Chemical Trading Co.,Ltd | +8613343047651 |
admin@zlchemi.com | China | 3692 | 58 |
| Shandong Deshang Chemical Co., Ltd. | +86-0531-8875-2665 +8613153039501 |
info@deshangchem.com | China | 662 | 58 |
벤조티아졸 관련 검색:
2-클로로벤조싸이아졸 2-히드록시벤조티아졸 2-벤조싸이아졸아민 2-메르캅토벤조티아졸 디벤조티아질 디설파이드 N-사이클로헥셀-벤조티아조릴 설펜아미드 벤조티아졸
Diltiazem hydrochloride
2-Amino-6-chlorobenzothiazole
2-Amino-6-methylbenzothiazole
2-Methyinaphtho[1,2-d]thiazole
2-Amino-6-methoxybenzothiazole
DIRECT PURE YELLOW 5G
2-(4-PIPERIDINYL)-1,3-BENZOTHIAZOLE
Thiazole
2,7-DICHLORO-4-METHYL-1,3-BENZOTHIAZOLE
2,5-DICHLORO-4-METHYL-1,3-BENZOTHIAZOLE
2-(6-CHLORO-3-PYRIDINYL)-1,3-BENZOTHIAZOLE