헥사놀(1-) C화학적 특성, 용도, 생산
개요
Hexyl alcohol has a fruity odor and aromatic flavor. May be
synthesized by reduction of n-caproic acid; the n-hexyl alcohol
represents one of the 14 possible isomers of this alcohol.
화학적 성질
1-Hexanol is a liquid at room temperature.The absolute perceived concentration has been reported as
0.01 ppm, and the recognition level is 0.09 ppm .
출처
Reported found among the constituents of several essential oils and aromas: apple, strawberry, tea, violet
(leaves and flowers), Java citronella, Bourbon geranium, lavender, lavandin, spike, Litsea zeylanica; also identified in bitter orange.
Also reported found in over 300 natural sources including apples, banana, sweet and sour cherry, citrus peel oils and juice, kumquat
peel oil, berries, guava, grapes, raisin, melon, papaya, peach, pear, pineapple, asparagus, kohlrabi, cabbage, celery, cucumber, lettuce,
leek, garlic, raw and cooked potato, sauerkraut, tomato, bell pepper, ginger, mint oils, mustard, breads, cheeses, butter, milk, fatty
fish, meats, cognac, whiskies, rum, cider, grape wines, coffee, tea, cocoa, peanut oil, pecans, soybeans, nuts, coconut meat and milk,
avocado, olive, passion fruit, plum, beans, mushrooms, starfruit, mango, fenugreek, sesame seed oil, figs, kelp, cardamom, coriander,
gin, rice, fruit brandies, prickly pear, licorice, lovage corn oil, endive, truffles and other sources
용도
1-Hexanol was examined as a perturbing agent on actomyosin ATPase and and was found to modulate the function of actomyosin motor via intermediate-specific structural perturbation.
정의
ChEBI: A primary alcohol that is hexane substituted by a hydroxy group at position 1.
생산 방법
1-Hexanol is commercially prepared from the addition of
ethylene to triethylaluminum followed by oxidation. It
is also produced from natural products derived from coconut
or palm oils.
제조 방법
By reduction of n-caproic acid; the n-hexyl alcohol represents 1 of the 14 possible isomers of this alcohol
일반 설명
1-Hexanol is an organic alcohol, which has application in the synthesis of antiseptics, fragrances, perfumes, etc. It is also used as a component of plasticizers.
위험도
Combustible.
건강위험
Recommended Personal Protective Equipment: Chemical gloves; chemical goggles; Symptoms Following Exposure: Liquid causes eye burns and skin irritation. Breathing vapors is not expected to cause systemic illness; General Treatment for Exposure: In case of contact, immediately flush skin and eyes with plenty of water. Wash eyes at least 15 min. and get medical care; Toxicity by Inhalation (Threshold Limit Value): Data not available; Short-Term Inhalation Limits: Data not available; Toxicity by Ingestion: Grade 2, LD
50 = 0.5 to 5 g/kg (rat); Late Toxicity: Data not available; Vapor (Gas) Irritant Characteristics: Data not available; Liquid or Solid Irritant Characteristics: Causes smarting of the skin and first-degree burns on short exposure; may cause second-degree burns on long exposure; Odor Threshold: Data not available.
화학 반응
Reactivity with Water No reaction; Reactivity with Common Materials: No reactions; Stability During Transport: Stable; Neutralizing Agents for Acids and Caustics: Not pertinent; Polymerization: Not pertinent; Inhibitor of Polymerization: Not pertinent.
Carcinogenicity
1-Hexanol was not a skin tumor
promoter when applied three times a week for 60 weeks to
mice skin that had been initiated with dimethylbenz[a]
anthracene.
Purification Methods
The commercial material usually contains other alcohols which are difficult to remove. A suitable method is to esterify with hydroxybenzoic acid, recrystallise the ester and saponify. [Olivier Recl Trav Chim, Pays-Bas 55 1027 1936.] Drying agents include K2CO3 and CaSO4, followed by filtration and distillation. (Some decomposition to the olefin occurs when Al amalgam is used as drying agent at room temperature, even if the amalgam is removed prior to distillation.) If the alcohol is required anhydrous, the redistilled material can be refluxed with the appropriate alkyl phthalate or succinate, as described under Ethanol. [Beilstein 1 IV 1694.]
헥사놀(1-) 준비 용품 및 원자재
원자재
준비 용품
