플루프레드니솔론

플루프레드니솔론
플루프레드니솔론 구조식 이미지
카스 번호:
53-34-9
한글명:
플루프레드니솔론
동의어(한글):
플루프레드니솔론
상품명:
Fluprednisolone
동의어(영문):
Alphadrol;U-7800;Etadrol;NSC-47439;fluprednisolone;6α-FLUPREDNISOLONE;6α-Fluprednisolone;6-a-Fluorprednisolone;6a-fluoroprednisolone;6-α-fluoroprednisolone
CBNumber:
CB8854834
분자식:
C21H27FO5
포뮬러 무게:
378.43
MOL 파일:
53-34-9.mol

플루프레드니솔론 속성

녹는점
208-213°
알파
D +92°
밀도
1.1023 (rough estimate)
굴절률
1.5980 (estimate)
저장 조건
Refrigerator
용해도
디옥산(약간 용해됨), DMSO(약간 용해됨), 메탄올(약간 용해됨)
색상
하얀색
수용성
174.2mg/L(20 ºC)
EPA
Fluprednisolone (53-34-9)

안전

WGK 독일 3
유해 물질 데이터 53-34-9(Hazardous Substances Data)

플루프레드니솔론 MSDS


6a-Fluoroprednisolone

플루프레드니솔론 C화학적 특성, 용도, 생산

개요

Fluprednisolone (6α-fluoro-11β,17,21-trihydroxy-pregna-1,4-diene-3,20-dione) is the 16-desmethyl analogue of paramethasone. Its activity is similar to that of paramethasone, and it has approximately 2.5 times the antirheumatic potency of prednisolone. With doses of 2 to 7 mg, evidence of salt and water retention has not been noted. The therapeutic index, however, probably is the same or only a little greater than that for prednisolone. Because no new adverse reactions have been noted during the administration of this drug on a short-term basis, it seems that a 6α-fluoro group does not deleteriously affect the activity of prednisolone (49,75).

용도

6α-Fluprednisolone is an anti-inflammatory corticosteroid metabolite.

플루프레드니솔론 준비 용품 및 원자재

원자재

준비 용품


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