Bafetinib
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- $19 - $6125
- Product name: Bafetinib
- CAS: 859212-16-1
- MF: C30H31F3N8O
- MW: 576.62
- EINECS:
- MDL Number:MFCD18633200
- Synonyms:Benzamide, N-(3-((4,5'-bipyrimidin)-2-ylamino)-4-methylphenyl)-4-(((3S)-3-(dimethylamino)-1-pyrrolidinyl)methyl)-3-(trifluoromethyl)-;Inno 406;Inno-406;4-[[(3S)-3-Dimethylaminopyrrolidin-1-yl]methyl]-N-[4-methyl-3-[(4-pyrimidin-5-ylpyrimidin-2-yl)amino]phenyl]-3-(trifluoromethyl)benzamide;Ns 187;Unii-nvw4Z03I9b;Bafetinib (INNO-406);N-[3-([4,5'-BipyriMidin]-2-ylaMino)-4-Methylphenyl]-4-[[(3S)-3-(diMethylaMino)-1-pyrrolidinyl]Methyl]-3-(trifluoroMethyl)benzaMide
62 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- Adipogen Life Sciences
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- AvaChem
- Axon Medchem
- Biorbyt Ltd
- Biosynth
- Cayman Chemical
- ChemScene
- DC Chemicals
- Labseeker
- TRC
- Usbiological
Package
- 10mM*1mLinDMSO(Solid+Solvent)
- 10mM*1mLinDMSO(Solution)
- 1mg
- 2mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 10mM*1mLinDMSO
- 200mg
- 250mg
- 1g
- 1mL(10mMinDMSO)
- Manufactureraablocks
- Product numberAA00GTUD
- Product descriptionBafetinib 98+%
- Packaging1mg
- Price$19
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00GTUD
- Product descriptionBafetinib ≥95%
- Packaging5mg
- Price$62
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00GTUD
- Product descriptionBafetinib
- Packaging10mg
- Price$104
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00GTUD
- Product descriptionBafetinib
- Packaging25mg
- Price$150
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00GTUD
- Product descriptionBafetinib
- Packaging50mg
- Price$179
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00GTUD
- Product descriptionBafetinib
- Packaging100mg
- Price$316
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00GTUD
- Product descriptionBafetinib
- Packaging200mg
- Price$404
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberM22584
- Product descriptionBafetinib 98%
- Packaging100MG
- Price$440
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberM22584
- Product descriptionBafetinib 98%
- Packaging25MG
- Price$190
- Updated2026-05-27
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberSYN-1179-M005
- Product descriptionBafetinib ≥95%
- Packaging5mg
- Price$184
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberSYN-1179-M001
- Product descriptionBafetinib ≥95%
- Packaging1mg
- Price$108
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberSYN-1179-M010
- Product descriptionBafetinib ≥95%
- Packaging10mg
- Price$335
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberSYN-1179-M050
- Product descriptionBafetinib ≥95%
- Packaging50mg
- Price$1015
- Updated2026-05-06
- Buy
- ManufacturerAK Scientific
- Product numberSYN1179
- Product descriptionBafetinib
- Packaging1mg
- Price$120
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA124910
- Product descriptionBafetinib 98+%
- Packaging50mg
- Price$156
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA124910
- Product descriptionBafetinib 98+%
- Packaging10mg
- Price$92
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA00GTUD | Bafetinib 98+% | 1mg | $19 | 2026-05-28 | Buy |
| aablocks | AA00GTUD | Bafetinib ≥95% | 5mg | $62 | 2026-05-28 | Buy |
| aablocks | AA00GTUD | Bafetinib | 10mg | $104 | 2026-05-28 | Buy |
| aablocks | AA00GTUD | Bafetinib | 25mg | $150 | 2026-05-28 | Buy |
| aablocks | AA00GTUD | Bafetinib | 50mg | $179 | 2026-05-28 | Buy |
| aablocks | AA00GTUD | Bafetinib | 100mg | $316 | 2026-05-28 | Buy |
| aablocks | AA00GTUD | Bafetinib | 200mg | $404 | 2026-05-28 | Buy |
| ACHEMBLOCK | M22584 | Bafetinib 98% | 100MG | $440 | 2026-05-27 | Buy |
| ACHEMBLOCK | M22584 | Bafetinib 98% | 25MG | $190 | 2026-05-27 | Buy |
| Adipogen Life Sciences | SYN-1179-M005 | Bafetinib ≥95% | 5mg | $184 | 2026-05-06 | Buy |
| Adipogen Life Sciences | SYN-1179-M001 | Bafetinib ≥95% | 1mg | $108 | 2026-05-06 | Buy |
| Adipogen Life Sciences | SYN-1179-M010 | Bafetinib ≥95% | 10mg | $335 | 2026-05-06 | Buy |
| Adipogen Life Sciences | SYN-1179-M050 | Bafetinib ≥95% | 50mg | $1015 | 2026-05-06 | Buy |
| AK Scientific | SYN1179 | Bafetinib | 1mg | $120 | 2021-12-16 | Buy |
| Ambeed | A124910 | Bafetinib 98+% | 50mg | $156 | 2021-12-16 | Buy |
| Ambeed | A124910 | Bafetinib 98+% | 10mg | $92 | 2021-12-16 | Buy |
Properties
Melting point :166-168°C
Density :1.36±0.1 g/cm3(Predicted)
storage temp. :Refrigerator
solubility :DMSO:42.0(Max Conc. mg/mL);72.84(Max Conc. mM)
form :A crystalline solid
pka :12.72±0.70(Predicted)
color :Light yellow to yellow
Density :1.36±0.1 g/cm3(Predicted)
storage temp. :Refrigerator
solubility :DMSO:42.0(Max Conc. mg/mL);72.84(Max Conc. mM)
form :A crystalline solid
pka :12.72±0.70(Predicted)
color :Light yellow to yellow
Safety Information
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| Signal word: | Warning | |||||||||||||||||||||
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Description
Bcr-Abl, a fusion protein with deregulated tyrosine kinase activity, is highly expressed in chronic myelogenous leukemia (CML). Bafetinib is a rationally developed tyrosine kinase inhibitor based on the chemical structure of imatinib , with modifications added to improve binding and potency against Bcr-Abl kinase (IC50 = 5.8 nM). It is 25- to 55-fold more potent than imatinib in vitro and ≥10-fold more potent in vivo. Bafetinib inhibits 12 out of the 13 most frequent imatinib-resistant Bcr-Abl point mutations, but not the T315I mutation and also targets the Src family kinase Lyn (IC50 = 19 nM), which has been associated with resistance to imatinib in CML.More related product prices
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Suppliers and manufacturers
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