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ChemicalBook >> CAS DataBase List >> Crizotinib

Crizotinib

Crizotinib price.
  • $5 - $1963.5
  • Product name: Crizotinib
  • CAS: 877399-52-5
  • MF: C21H22Cl2FN5O
  • MW: 450.34
  • EINECS:638-814-9
  • MDL Number:MFCD12407409
  • Synonyms:(R)-3-[1-(2,6-Dichloro-3-fluorophenyl)ethoxy]-5-(1-piperidin-4-yl-1H- pyrazol-4-yl)pyridin-2-ylaMine;[3-[[(R)-1-(2,6-Dichloro-3- fluorophenyl)ethyl]oxy]-5-[1-(piperidin-4-yl)-1H-pyrazol-4-yl]pyridin-2-yl]aMine;2-PyridinaMine, 3-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[1-(4-piperidinyl)-1H-pyrazol-4-yl]-;Crozotinib;Crizotinib,PF-02341066;Crizotinib (PF2341066);PF-02341066 Crizotinib;3-((R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1-(piperidin-4-yl)-1H-pyrazol-4-yl)pyridin-2-amine
Price116 Properties Safety Information Description
116 prices
Selected condition：
Brand
  • aablocks
  • AccelPharmtech
  • ACHEMBLOCK
  • Adipogen Life Sciences
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Apolloscientific
  • Arctom
  • AvaChem
  • Axon Medchem
  • Biorbyt Ltd
  • Biosynth
  • Cayman Chemical
  • ChemScene
  • DC Chemicals
  • Matrix Scientific
  • Sigma-Aldrich
  • Thermo Scientific Chemicals
  • Tocris
Package
  • 10mM(1mLinDMSO)
  • 10mM*1mLinDMSO(Solid+Solvent)
  • 1unit
  • 10mM(in1mLDMSO)
  • 5mg
  • 20mg
  • 50
  • 1mg
  • 10mg
  • 10mM*1mLinDMSO(Solution)
  • 10mM*1mLinDMSO
  • 10
  • 25mg
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  • 1.00g
  • 5.00g
  • 25.00g
  • 1 g
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  • 0.1g
  • 200mg
  • 250mg
  • 0.25g
  • 10mM(in 1mL DMSO)
  • 0.5g
  • 1g
  • 2g
  • 5g
  • 25g
  • Manufactureraablocks
  • Product numberAA00368K
  • Product description3-[(1R)-1-(2,6-Dichloro-3-fluorophenyl)ethoxy]-5-[1-(4-piperidinyl)-1H-pyrazol-4-yl]pyridin-2-amine 98%
  • Packaging1mg
  • Price$8
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00368K
  • Product description3-[(1R)-1-(2,6-Dichloro-3-fluorophenyl)ethoxy]-5-[1-(4-piperidinyl)-1H-pyrazol-4-yl]pyridin-2-amine 98%
  • Packaging10mg
  • Price$10
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00368K
  • Product description3-[(1R)-1-(2,6-Dichloro-3-fluorophenyl)ethoxy]-5-[1-(4-piperidinyl)-1H-pyrazol-4-yl]pyridin-2-amine 98%
  • Packaging25mg
  • Price$12
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00368K
  • Product description3-[(1R)-1-(2,6-Dichloro-3-fluorophenyl)ethoxy]-5-[1-(4-piperidinyl)-1H-pyrazol-4-yl]pyridin-2-amine 98%
  • Packaging50mg
  • Price$15
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00368K
  • Product description3-[(1R)-1-(2,6-Dichloro-3-fluorophenyl)ethoxy]-5-[1-(4-piperidinyl)-1H-pyrazol-4-yl]pyridin-2-amine 98%
  • Packaging100mg
  • Price$18
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00368K
  • Product description3-[(1R)-1-(2,6-Dichloro-3-fluorophenyl)ethoxy]-5-[1-(4-piperidinyl)-1H-pyrazol-4-yl]pyridin-2-amine 98%
  • Packaging250mg
  • Price$22
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00368K
  • Product description3-[(1R)-1-(2,6-Dichloro-3-fluorophenyl)ethoxy]-5-[1-(4-piperidinyl)-1H-pyrazol-4-yl]pyridin-2-amine 95%
  • Packaging1g
  • Price$63
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00368K
  • Product description3-[(1R)-1-(2,6-Dichloro-3-fluorophenyl)ethoxy]-5-[1-(4-piperidinyl)-1H-pyrazol-4-yl]pyridin-2-amine 98%
  • Packaging5g
  • Price$155
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00368K
  • Product description3-[(1R)-1-(2,6-Dichloro-3-fluorophenyl)ethoxy]-5-[1-(4-piperidinyl)-1H-pyrazol-4-yl]pyridin-2-amine 95%
  • Packaging25g
  • Price$557
  • Updated2026-05-28
  • Buy
  • ManufacturerAccelPharmtech
  • Product numberHJ1487
  • Product descriptionCrizotinib 98.00%
  • Packaging1G
  • Price$170
  • Updated2026-05-21
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberG-6372
  • Product descriptionCrizotinib 98%
  • Packaging5G
  • Price$170
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberG-6372
  • Product descriptionCrizotinib 98%
  • Packaging1G
  • Price$50
  • Updated2026-05-27
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberCDX-C0699-M010
  • Product descriptionCrizotinib ≥98%(HPLC)
  • Packaging10mg
  • Price$105
  • Updated2026-05-06
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberCDX-C0699-M050
  • Product descriptionCrizotinib ≥98%(HPLC)
  • Packaging50mg
  • Price$316
  • Updated2026-05-06
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ20633
  • Product descriptionCrizotinib 98%(HPLC)
  • Packaging5g
  • Price$273
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ20633
  • Product descriptionCrizotinib 98%(HPLC)
  • Packaging1g
  • Price$97
  • Updated2026-06-04
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA00368K 3-[(1R)-1-(2,6-Dichloro-3-fluorophenyl)ethoxy]-5-[1-(4-piperidinyl)-1H-pyrazol-4-yl]pyridin-2-amine 98% 1mg $8 2026-05-28 Buy
aablocks AA00368K 3-[(1R)-1-(2,6-Dichloro-3-fluorophenyl)ethoxy]-5-[1-(4-piperidinyl)-1H-pyrazol-4-yl]pyridin-2-amine 98% 10mg $10 2026-05-28 Buy
aablocks AA00368K 3-[(1R)-1-(2,6-Dichloro-3-fluorophenyl)ethoxy]-5-[1-(4-piperidinyl)-1H-pyrazol-4-yl]pyridin-2-amine 98% 25mg $12 2026-05-28 Buy
aablocks AA00368K 3-[(1R)-1-(2,6-Dichloro-3-fluorophenyl)ethoxy]-5-[1-(4-piperidinyl)-1H-pyrazol-4-yl]pyridin-2-amine 98% 50mg $15 2026-05-28 Buy
aablocks AA00368K 3-[(1R)-1-(2,6-Dichloro-3-fluorophenyl)ethoxy]-5-[1-(4-piperidinyl)-1H-pyrazol-4-yl]pyridin-2-amine 98% 100mg $18 2026-05-28 Buy
aablocks AA00368K 3-[(1R)-1-(2,6-Dichloro-3-fluorophenyl)ethoxy]-5-[1-(4-piperidinyl)-1H-pyrazol-4-yl]pyridin-2-amine 98% 250mg $22 2026-05-28 Buy
aablocks AA00368K 3-[(1R)-1-(2,6-Dichloro-3-fluorophenyl)ethoxy]-5-[1-(4-piperidinyl)-1H-pyrazol-4-yl]pyridin-2-amine 95% 1g $63 2026-05-28 Buy
aablocks AA00368K 3-[(1R)-1-(2,6-Dichloro-3-fluorophenyl)ethoxy]-5-[1-(4-piperidinyl)-1H-pyrazol-4-yl]pyridin-2-amine 98% 5g $155 2026-05-28 Buy
aablocks AA00368K 3-[(1R)-1-(2,6-Dichloro-3-fluorophenyl)ethoxy]-5-[1-(4-piperidinyl)-1H-pyrazol-4-yl]pyridin-2-amine 95% 25g $557 2026-05-28 Buy
AccelPharmtech HJ1487 Crizotinib 98.00% 1G $170 2026-05-21 Buy
ACHEMBLOCK G-6372 Crizotinib 98% 5G $170 2026-05-27 Buy
ACHEMBLOCK G-6372 Crizotinib 98% 1G $50 2026-05-27 Buy
Adipogen Life Sciences CDX-C0699-M010 Crizotinib ≥98%(HPLC) 10mg $105 2026-05-06 Buy
Adipogen Life Sciences CDX-C0699-M050 Crizotinib ≥98%(HPLC) 50mg $316 2026-05-06 Buy
AK Scientific J20633 Crizotinib 98%(HPLC) 5g $273 2026-06-04 Buy
AK Scientific J20633 Crizotinib 98%(HPLC) 1g $97 2026-06-04 Buy
Next Last

Properties

Melting point :192 °C
Boiling point :599.2±50.0 °C(Predicted)
Density :1.47±0.1 g/cm3(Predicted)
storage temp. :room temp
solubility :Soluble in DMSO (up to 25 mg/ml with warming) or in Ethanol (up to 25 mg/ml with warming)
pka :9.81±0.10(Predicted)
form :powder
color :white to tan
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.
InChI :1S/C21H22Cl2FN5O/c1-12(19-16(22)2-3-17(24)20(19)23)30-18-8-13(9-27-21(18)25)14-10-28-29(11-14)15-4-6-26-7-5-15/h2-3,8-12,15,26H,4-7H2,1H3,(H2,25,27)/t12-/m1/s1
InChIKey :KTEIFNKAUNYNJU-GFCCVEGCSA-N
SMILES :C1(N)=NC=C(C2=CN(C3CCNCC3)N=C2)C=C1O[C@@H](C1=C(Cl)C=CC(F)=C1Cl)C
CAS DataBase Reference :877399-52-5

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)Health Hazard (GHS08)Environment (GHS09)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H317 May cause an allergic skin reaction Sensitisation, Skin Category 1 Warning P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H341 Suspected of causing genetic defects Germ cell mutagenicity Category 2 Warning P201,P202, P281, P308+P313, P405,P501
H400 Very toxic to aquatic life Hazardous to the aquatic environment, acute hazard Category 1 Warning P273, P391, P501
Precautionary statements:
P201 Obtain special instructions before use.
P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P308+P313 IF exposed or concerned: Get medical advice/attention.

Description

Crizotinib is a potent and selective dual inhibitor of mesenchymal-epithelial transition factor (c-MET) kinase and anaplastic lymphoma kinase (ALK). Crizotinib is a potential antitumor agent. In August 2011, the United States FDA approved crizotinib for the treatment of anaplastic lymphoma kinase (ALK) rearranged non-small-cell lung cancer (NSCLC).

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Suppliers and manufacturers

Hainan Chenghe Pharmaceutical Technology Co., Ltd Hangzhou Chemtrue Bio-Tech Co.,Ltd. Tai Zhou World Pharm & Chem Co., Ltd Shanghai?Medlife?Pharm-Tech?Co.,?Ltd Cangzhou Enke Pharma Tech Co.,ltd. Beijing Huikang Boyuan Chemical Tech Co., Ltd Cangzhou Nianke Pharmaceutical Technology Co., Ltd. Hubei Yuanmeng Biological Technology Co., Ltd. Guangzhou Wanqian Pharmaceutical Technology Co., Ltd Shanghai Boyle Chemical Co., Ltd.