EAI-045
|
- $7 - $1575
- Product name: EAI-045
- CAS: 1942114-09-1
- MF: C19H14FN3O3S
- MW: 383.4
- EINECS:-0
- MDL Number:MFCD30187871
- Synonyms:EAI-045;2-(5-fluoro-2-hydroxyphenyl)-2-(1-oxoisoindolin-2-yl)-N-(thiazol-2-yl)acetamide;EA1045;α-(5-fluoro-2-hydroxyphenyl)-1,3-dihydro-1-oxo-N-2-thiazolyl-2H-Isoindole-2-acetamide;EAI 045;EAI-045;CS-2350;EAI045;EAI 045;EAI-045;N-(3-((5-fluoroethoxy)phenyl)amino)pyrimidin-4-yl)amino)phenyl)acrylamide (EAI-045)
52 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- AvaChem
- Axon Medchem
- Biosynth
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- Matrix Scientific
- Medical Isotopes, Inc.
- TRC
Package
- 10mM*1mLinDMSO
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250.00mg
- 250mg
- 1.00g
- 1g
- 5G
- 5.00g
- Manufactureraablocks
- Product numberAA00ABON
- Product descriptionEAI045 97%
- Packaging1mg
- Price$8
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00ABON
- Product descriptionEAI045 97%
- Packaging5mg
- Price$10
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00ABON
- Product descriptionEAI045 97%
- Packaging10mg
- Price$12
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00ABON
- Product descriptionEAI045 97%
- Packaging25mg
- Price$15
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00ABON
- Product descriptionEAI045 97%
- Packaging50mg
- Price$20
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00ABON
- Product descriptionEAI045 97%
- Packaging100mg
- Price$27
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00ABON
- Product descriptionEAI045 97%
- Packaging250mg
- Price$38
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00ABON
- Product descriptionEAI045 97%
- Packaging1g
- Price$95
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberM15358
- Product descriptionEAI045 98%
- Packaging5G
- Price$252
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberM15358
- Product descriptionEAI045 98%
- Packaging1G
- Price$90
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberM15358
- Product descriptionEAI045 98%
- Packaging100MG
- Price$27
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product number5125EG
- Product descriptionCID121231412
- Packaging10mg
- Price$185
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA105328
- Product description2-(5-Fluoro-2-hydroxyphenyl)-2-(1-oxoisoindolin-2-yl)-N-(thiazol-2-yl)acetamide 97%
- Packaging5mg
- Price$7
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA105328
- Product description2-(5-Fluoro-2-hydroxyphenyl)-2-(1-oxoisoindolin-2-yl)-N-(thiazol-2-yl)acetamide 97%
- Packaging1g
- Price$109
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA105328
- Product description2-(5-Fluoro-2-hydroxyphenyl)-2-(1-oxoisoindolin-2-yl)-N-(thiazol-2-yl)acetamide 97%
- Packaging50mg
- Price$20
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA105328
- Product description2-(5-Fluoro-2-hydroxyphenyl)-2-(1-oxoisoindolin-2-yl)-N-(thiazol-2-yl)acetamide 97%
- Packaging25mg
- Price$14
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA00ABON | EAI045 97% | 1mg | $8 | 2026-05-28 | Buy |
| aablocks | AA00ABON | EAI045 97% | 5mg | $10 | 2026-05-28 | Buy |
| aablocks | AA00ABON | EAI045 97% | 10mg | $12 | 2026-05-28 | Buy |
| aablocks | AA00ABON | EAI045 97% | 25mg | $15 | 2026-05-28 | Buy |
| aablocks | AA00ABON | EAI045 97% | 50mg | $20 | 2026-05-28 | Buy |
| aablocks | AA00ABON | EAI045 97% | 100mg | $27 | 2026-05-28 | Buy |
| aablocks | AA00ABON | EAI045 97% | 250mg | $38 | 2026-05-28 | Buy |
| aablocks | AA00ABON | EAI045 97% | 1g | $95 | 2026-05-28 | Buy |
| ACHEMBLOCK | M15358 | EAI045 98% | 5G | $252 | 2026-05-27 | Buy |
| ACHEMBLOCK | M15358 | EAI045 98% | 1G | $90 | 2026-05-27 | Buy |
| ACHEMBLOCK | M15358 | EAI045 98% | 100MG | $27 | 2026-05-27 | Buy |
| AK Scientific | 5125EG | CID121231412 | 10mg | $185 | 2021-12-16 | Buy |
| Ambeed | A105328 | 2-(5-Fluoro-2-hydroxyphenyl)-2-(1-oxoisoindolin-2-yl)-N-(thiazol-2-yl)acetamide 97% | 5mg | $7 | 2021-12-16 | Buy |
| Ambeed | A105328 | 2-(5-Fluoro-2-hydroxyphenyl)-2-(1-oxoisoindolin-2-yl)-N-(thiazol-2-yl)acetamide 97% | 1g | $109 | 2021-12-16 | Buy |
| Ambeed | A105328 | 2-(5-Fluoro-2-hydroxyphenyl)-2-(1-oxoisoindolin-2-yl)-N-(thiazol-2-yl)acetamide 97% | 50mg | $20 | 2021-12-16 | Buy |
| Ambeed | A105328 | 2-(5-Fluoro-2-hydroxyphenyl)-2-(1-oxoisoindolin-2-yl)-N-(thiazol-2-yl)acetamide 97% | 25mg | $14 | 2021-12-16 | Buy |
Properties
Density :1.546±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :≥38.3 mg/mL in DMSO; insoluble in H2O; insoluble in EtOH
form :solid
pka :7.20±0.50(Predicted)
color :White to khaki
InChI :InChI=1S/C19H14FN3O3S/c20-12-5-6-15(24)14(9-12)16(17(25)22-19-21-7-8-27-19)23-10-11-3-1-2-4-13(11)18(23)26/h1-9,16,24H,10H2,(H,21,22,25)
InChIKey :YTUFHOKUFOQRDF-UHFFFAOYSA-N
SMILES :C(C1C=C(F)C=CC=1O)(N1CC2=CC=CC=C2C1=O)C(=O)NC1SC=CN=1
storage temp. :2-8°C
solubility :≥38.3 mg/mL in DMSO; insoluble in H2O; insoluble in EtOH
form :solid
pka :7.20±0.50(Predicted)
color :White to khaki
InChI :InChI=1S/C19H14FN3O3S/c20-12-5-6-15(24)14(9-12)16(17(25)22-19-21-7-8-27-19)23-10-11-3-1-2-4-13(11)18(23)26/h1-9,16,24H,10H2,(H,21,22,25)
InChIKey :YTUFHOKUFOQRDF-UHFFFAOYSA-N
SMILES :C(C1C=C(F)C=CC=1O)(N1CC2=CC=CC=C2C1=O)C(=O)NC1SC=CN=1
Safety Information
| Symbol(GHS): |
|
|||||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Signal word: | Warning | |||||||||||||||||||||||||||||||||||
| Hazard statements: |
|
|||||||||||||||||||||||||||||||||||
| Precautionary statements: |
|
Description
EAI045 is a potent and selective EGFR inhibitor (fourth generation). EAI045 targets selected drug-resistant EGFR mutants without affecting the wild-type receptor. EAI045 inhibits L858R/T790M-mutant EGFR with low-nanomolar potency in biochemical assays. Therefore, it is a potential candidate drug for the treatment of related non-small cell lung cancer (NSCLC). It should be noted that EAI-045 is effectively in targeting the EGFR C797S mutation, which is resistance to the third-generation EGFR inhibitors including AZD9291 (osimertinib) and CO-1686 (rociletinib).More related product prices
Neratinib 1256580-46-7 918505-84-7 Nintedanib Olaparib Nintedanib Ethanesulfonate Salt PLERIXAFOR Afatinib (BIBW 2992) Crizotinib 918504-65-1Related product price
-
Neratinib
$10-5273 -
1256580-46-7
$8-1872 -
918505-84-7
$9-1133.9
