NU6140
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- $32 - $2691
- Product name: NU6140
- CAS: 444723-13-1
- MF: C23H30N6O2
- MW: 422.52
- EINECS:
- MDL Number:MFCD09264153
- Synonyms:NU6140;4-[[6-(Cyclohexylmethoxy)-1H-purin-2-yl]amino]-N,N-diethylbenzamide;4-[[6-(cyclohexylmethoxy)-7H-purin-2-yl]amino]-N,N-diethylbenzamide;Benzamide, 4-[[6-(cyclohexylmethoxy)-9H-purin-2-yl]amino]-N,N-diethyl-;CDK,Inhibitor,NU6140,Aurora Kinase,inhibit,NU 6140,NU-6140,Cyclin dependent kinase;NU6140, 10 mM in DMSO
26 prices
Selected condition：
Brand
- Ambeed
- American Custom Chemicals Corporation
- Arctom
- Cayman Chemical
- ChemScene
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 500μg
- 1mg
- 50mg
- 50
- 25 mg
- 5 mg
- 10
- 10mM*1mLinDMSO(Solution)
- 5MG
- 100mg
- 250mg
- 1g
- 10mg
- 25mg
- 10mM*1mLinDMSO(Solid+Solvent)
- ManufacturerAmbeed
- Product numberA1176612
- Product description4-((6-(Cyclohexylmethoxy)-7H-purin-2-yl)amino)-N,N-diethylbenzamide 99%
- Packaging100mg
- Price$718
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA1176612
- Product description4-((6-(Cyclohexylmethoxy)-7H-purin-2-yl)amino)-N,N-diethylbenzamide 99%
- Packaging250mg
- Price$1077
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA1176612
- Product description4-((6-(Cyclohexylmethoxy)-7H-purin-2-yl)amino)-N,N-diethylbenzamide 99%
- Packaging1g
- Price$2691
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0002495
- Product descriptionNU-6140 95.00%
- Packaging5MG
- Price$317.9
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberHY-107419
- Product descriptionNU6140 99.53%
- Packaging25mg
- Price$271
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-107419
- Product descriptionNU6140 99.53%
- Packaging10mg
- Price$133
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-107419
- Product descriptionNU6140 99.53%
- Packaging5mg
- Price$84
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-107419
- Product descriptionNU6140 99.53%
- Packaging10mM*1mLinDMSO(Solid+Solvent)
- Price$87
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-107419
- Product descriptionNU6140 99.53%
- Packaging10mM*1mLinDMSO(Solution)
- Price$92
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-107419
- Product descriptionNU6140 99.53%
- Packaging50mg
- Price$380
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-107419
- Product descriptionNU6140 99.53%
- Packaging100mg
- Price$527
- Updated2026-05-26
- Buy
- ManufacturerCayman Chemical
- Product number17271
- Product descriptionNU 6140 ≥98%
- Packaging500μg
- Price$32
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17271
- Product descriptionNU 6140 ≥98%
- Packaging500μg
- Price$36
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number17271
- Product descriptionNU 6140 ≥98%
- Packaging1mg
- Price$57
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17271
- Product descriptionNU 6140 ≥98%
- Packaging1mg
- Price$63
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number17271
- Product descriptionNU 6140 ≥98%
- Packaging5mg
- Price$139
- Updated2024-03-01
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Ambeed | A1176612 | 4-((6-(Cyclohexylmethoxy)-7H-purin-2-yl)amino)-N,N-diethylbenzamide 99% | 100mg | $718 | 2021-12-16 | Buy |
| Ambeed | A1176612 | 4-((6-(Cyclohexylmethoxy)-7H-purin-2-yl)amino)-N,N-diethylbenzamide 99% | 250mg | $1077 | 2021-12-16 | Buy |
| Ambeed | A1176612 | 4-((6-(Cyclohexylmethoxy)-7H-purin-2-yl)amino)-N,N-diethylbenzamide 99% | 1g | $2691 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0002495 | NU-6140 95.00% | 5MG | $317.9 | 2021-12-16 | Buy |
| Arctom | HY-107419 | NU6140 99.53% | 25mg | $271 | 2026-05-26 | Buy |
| Arctom | HY-107419 | NU6140 99.53% | 10mg | $133 | 2026-05-26 | Buy |
| Arctom | HY-107419 | NU6140 99.53% | 5mg | $84 | 2026-05-26 | Buy |
| Arctom | HY-107419 | NU6140 99.53% | 10mM*1mLinDMSO(Solid+Solvent) | $87 | 2026-05-26 | Buy |
| Arctom | HY-107419 | NU6140 99.53% | 10mM*1mLinDMSO(Solution) | $92 | 2026-05-26 | Buy |
| Arctom | HY-107419 | NU6140 99.53% | 50mg | $380 | 2026-05-26 | Buy |
| Arctom | HY-107419 | NU6140 99.53% | 100mg | $527 | 2026-05-26 | Buy |
| Cayman Chemical | 17271 | NU 6140 ≥98% | 500μg | $32 | 2024-03-01 | Buy |
| Cayman Chemical | 17271 | NU 6140 ≥98% | 500μg | $36 | 2026-04-30 | Buy |
| Cayman Chemical | 17271 | NU 6140 ≥98% | 1mg | $57 | 2024-03-01 | Buy |
| Cayman Chemical | 17271 | NU 6140 ≥98% | 1mg | $63 | 2026-04-30 | Buy |
| Cayman Chemical | 17271 | NU 6140 ≥98% | 5mg | $139 | 2024-03-01 | Buy |
Properties
Boiling point :707.8±70.0 °C(Predicted)
Density :1.234±0.06 g/cm3(Predicted)
storage temp. :Desiccate at +4°C
solubility :DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 30 mg/ml; Ethanol:PBS (pH 7.2) (1:3): 0.25 mg/ml
form :White to off-white solid.
pka :9.41±0.10(Predicted)
color :White to light yellow
InChI :1S/C23H30N6O2/c1-3-29(4-2)22(30)17-10-12-18(13-11-17)26-23-27-20-19(24-15-25-20)21(28-23)31-14-16-8-6-5-7-9-16/h10-13,15-16H,3-9,14H2,1-2H3,(H2,24,25,26,27,28)
InChIKey :XHEQSRJCJTWWAH-UHFFFAOYSA-N
SMILES :O=C(N(CC)CC)C1=CC=C(NC2=NC(NC=N3)=C3C(OCC4CCCCC4)=N2)C=C1
Density :1.234±0.06 g/cm3(Predicted)
storage temp. :Desiccate at +4°C
solubility :DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 30 mg/ml; Ethanol:PBS (pH 7.2) (1:3): 0.25 mg/ml
form :White to off-white solid.
pka :9.41±0.10(Predicted)
color :White to light yellow
InChI :1S/C23H30N6O2/c1-3-29(4-2)22(30)17-10-12-18(13-11-17)26-23-27-20-19(24-15-25-20)21(28-23)31-14-16-8-6-5-7-9-16/h10-13,15-16H,3-9,14H2,1-2H3,(H2,24,25,26,27,28)
InChIKey :XHEQSRJCJTWWAH-UHFFFAOYSA-N
SMILES :O=C(N(CC)CC)C1=CC=C(NC2=NC(NC=N3)=C3C(OCC4CCCCC4)=N2)C=C1
Safety Information
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| Signal word: | Warning | |||||||||||||||||||||||||||||||||||
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Description
NU 6140 is a cyclin-dependent kinase 2 (Cdk2) inhibitor (IC50 = 0.41 μM) that demonstrates 10- to 36-fold selectivity against Cdk2-cyclin A compared to Cdk1-cyclin B, Cdk4-cyclin D, Cdk5-p25, or Cdk7-cyclin H. NU 6140 has been found to induce cell-cycle arrest at the G2-M phase and to potentiate the apoptotic effect of paclitaxel in HeLa cells by inhibiting the anti-apoptotic protein, survivin.More related product prices
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