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3-Hydroxy-3-methyl-2-butanone

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Company Name: Capot Chemical Co.,Ltd.
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Email: sales@capotchem.com
Products Intro: Product Name:3-Hydroxy-3-methyl-2-butanone
CAS:115-22-0
Purity:98%(Min,HPLC) Package:100g;1kg;5kg,10kg,25kg,50kg
Company Name: career henan chemical co
Tel: +86-0371-86658258
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Products Intro: Product Name:3-HYDROXY-3-METHYL-2-BUTANONE
CAS:115-22-0
Purity:98% Package:1kg;1USD
Company Name: SHANDONG ZHI SHANG CHEMICAL CO.LTD
Tel: +86 18953170293
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Products Intro: Product Name:3-Hydro xy-3-m ethyl-2-butanone
CAS:115-22-0
Package:2.5KG;500G
Company Name: Chongqing Chemdad Co., Ltd
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Products Intro: Product Name:3-Hydroxy-3-methyl-2-butanone
CAS:115-22-0
Purity:0.98 Package:1kg,2kg,5kg,10kg,25kg
Company Name: Alchem Pharmtech,Inc.
Tel: 8485655694
Email: sales@alchempharmtech.com
Products Intro: Product Name:3-Hydroxy-3-Methyl-2-butanone
CAS:115-22-0
Purity:97+% Package:1g;10g;100g;;1kg Remarks:Z-70440

3-Hydroxy-3-methyl-2-butanone manufacturers

3-Hydroxy-3-methyl-2-butanone Basic information
Product Name:3-Hydroxy-3-methyl-2-butanone
Synonyms:3-HYDROXY-3-METHYL-2-BUTANONE;ACETYLDIMETHYLCARBINOL;1-Hydroxy-1-methylethyl methyl ketone;2-Butanone, 3-hydroxy-3-methyl-;2-Hydroxy-2-methyl-3-butanone;2-Methyl-2-hydroxybutan-3-one;3-hydroxy-3-methyl-2-butanon;3-Hydroxy-3-methylbutanone
CAS:115-22-0
MF:C5H10O2
MW:102.13
EINECS:204-073-1
Product Categories:C3 to C6;Carbonyl Compounds;Ketones
Mol File:115-22-0.mol
3-Hydroxy-3-methyl-2-butanone Structure
3-Hydroxy-3-methyl-2-butanone Chemical Properties
Melting point 84-85 °C
Boiling point 140-141 °C (lit.)
density 0.971 g/mL at 25 °C (lit.)
refractive index n20/D 1.415(lit.)
Fp 108 °F
storage temp. Flammables area
solubility Soluble in chloroform.
pka13.28±0.29(Predicted)
form Liquid
color Clear colorless to yellow or light red
BRN 1616385
InChIKeyBNDRWEVUODOUDW-UHFFFAOYSA-N
CAS DataBase Reference115-22-0(CAS DataBase Reference)
EPA Substance Registry System2-Butanone, 3-hydroxy-3-methyl- (115-22-0)
Safety Information
Risk Statements 10
Safety Statements 23-24/25-22
RIDADR UN 1224 3/PG 3
WGK Germany 3
TSCA Yes
HazardClass 3
PackingGroup III
HS Code 29144000
MSDS Information
ProviderLanguage
ACROS English
SigmaAldrich English
ALFA English
3-Hydroxy-3-methyl-2-butanone Usage And Synthesis
Chemical PropertiesCLEAR COLOURLESS TO LIGHT YELLOW LIQUID
Uses3-Hydroxy-3-methyl-2-butanone used to produce 2,5-dihydroxy-2-methyl-heptan-3-one, laboratory chemicals.
Application3-Hydroxy-3-methyl-2-butanone is an alpha-hydroxy ketone compound. It can be used as a biologically active natural product and a pharmaceutical intermediate, and as a photoinitiator in UV-curable coatings. At the same time, α-hydroxyketone structural units are also widely used synthons in organic synthesis. Hydroxyl can be used as a mild reaction precursor for double bonds, ester groups, carbonyl groups, halogenated hydrocarbons and other groups. Carbonyl can be used as the reaction precursor of hydroxyl, amino, alkyl and other groups. Therefore, α-hydroxyketone compounds are a class of compounds with important application value.
Preparationsynthesis of 3-Hydroxy-3-methyl-2-butanone: 19ml of concentrated sulfuric acid (98wt%) was slowly mixed with 100ml of water, then 13g of yellow mercury oxide was added within 1.5h, 84g (1.0mol) of 2-methyl-3-butyn-2-ol was added dropwise to the sulfuric acid solution containing mercury oxide at 65-75°C, Then the reaction was stirred at 65-75°C for 30min, cooled to room temperature after the reaction was completed, the reaction product was subjected to suction filtration, the filtrate after suction filtration was extracted with ether (3×20ml), and the organic phase after extraction was water and hydrogen carbonate respectively. Washed with sodium solution, the washed organic phase was dried with anhydrous magnesium sulfate, and then filtered, the filtered filtrate was concentrated by rotary evaporation and then distilled, and the 140°C fraction was collected, 45.6 g of light yellow liquid was obtained as 3-hydroxy-3-methyl-2-butanone, and the yield was 32.2%.
3-Hydroxy-3-methyl-2-butanone Preparation Products And Raw materials
Preparation Products3-Methyl-3-buten-2-one-->2,3,3-Trimethyl-5-methoxy-3H-indole
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