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Nifuratel

Nifuratel Suppliers list
Company Name: Henan DaKen Chemical CO.,LTD.
Tel: +86-371-55531817
Email: info@dakenchem.com
Products Intro: Product Name:Nifuratel
CAS:4936-47-4
Purity:99.00% Package:100g,500g,1KG,10KG,100KG
Company Name: Henan Tianfu Chemical Co.,Ltd.
Tel: 0371-55170693
Email: info@tianfuchem.com
Products Intro: Product Name:Nifuratel
CAS:4936-47-4
Purity:0.99 Package:25KG,5KG;1KG;500G
Company Name: career henan chemical co
Tel: +86-371-86658258
Email: sales@coreychem.com
Products Intro: Product Name:Nifuratel
CAS:4936-47-4
Purity:98% Package:1KG;1USD
Company Name: Jinan Jianfeng Chemical Co., Ltd
Tel: 15562555968
Email: info@pharmachemm.com
Products Intro: Product Name:Nifuratel
CAS:4936-47-4
Purity:99% Package:5KG;1KG;25kg Remarks:pharm intermediate
Company Name: Shenzhen Nexconn Pharmatechs Ltd
Tel: 15013857715
Email: admin@nexconn.com
Products Intro: Product Name:Nifuratel
CAS:4936-47-4
Purity:95% Package:1KG;25KG

Lastest Price from Nifuratel manufacturers

  • Nifuratel
  • US $1.00 / Kg/Drum
  • 2019-10-30
  • CAS:4936-47-4
  • Min. Order: 25Kg/Drum
  • Purity: 99%
  • Supply Ability: 1ton
  • Nifuratel
  • US $1.00 / KG
  • 2019-07-06
  • CAS:4936-47-4
  • Min. Order: 1G
  • Purity: 98%
  • Supply Ability: 100KG
Nifuratel Basic information
The main effects
Product Name:Nifuratel
Synonyms:Nifuratel, >99%;Nifuratel ,98%;5-[(Methylsulfanyl)Methyl]-4-[(E)-[(5-nitrofuran-2-yl)Methylidene]aMino]-1,3-oxazolidin-2-one;Inimur;Tydantil;5-[(methylthio)methyl]-3-[(Z)-(5-nitro-2-furanyl)methylideneamino]-2-oxazolidinone;3-[(5-Nitro-2-furfurylidene)aMino]-5-[(Methylthio)Methyl]-2-oxazolidinone;5-(MethylMercaptoMethyl)-3-(5-nitro-2-furfurylidenaMino)-2-oxazolidinone
CAS:4936-47-4
MF:C10H11N3O5S
MW:285.28
EINECS:225-576-2
Product Categories:Pharmaceuticals;APIS;API;Intermediates & Fine Chemicals;TCI-
Mol File:4936-47-4.mol
Nifuratel Structure
Nifuratel Chemical Properties
Melting point 176-178°C
Boiling point 423.6±53.0 °C(Predicted)
density 1.57±0.1 g/cm3(Predicted)
storage temp. -20°C Freezer
pka-2.49±0.40(Predicted)
CAS DataBase Reference4936-47-4(CAS DataBase Reference)
Safety Information
Risk Statements 68
Safety Statements 36/37
HS Code 29321900
ToxicityLD50 oral in mouse: > 4500mg/kg
MSDS Information
Nifuratel Usage And Synthesis
The main effectsNifuratel is a derivative of nitrofuran , it is a broad spectrum antibiotic with broad-spectrum antimicrobial effect, Nystatin is a polyene antifungal,it has strong effects on trichomoniasis, bacteria, Candida albicans , it plays a strong killing role especially in common pathogens for gynecological infections such as gram-positive and gram-negative bacteria, trichomoniasis, mold, chlamydia and mycoplasma . After oral administration, it is absorbed by gastrointestinal ,most of it is excreted through the kidneys, it has higher concentrations in blood, urine, genital tissues ,so it can have a strong antibacterial effect in the urinary system, and its metabolites still have antibacterial activity, and it is excreted through the urine . Oral nifuratel can be rapidly absorbed, after oral administration of 200mg, the peak plasma concentration is 9.48μg/L in two hours . The animals acute toxicity test proves that in toxicity of the product is mild.
Nifuratel indications include:
1, bacterial vaginosis, trichomonas vaginitis, vulvovaginal candidiasis, vaginal mixed infections.
2, urinary tract infections.
3, gastrointestinal amoebiasis and trichomoniasis Jia.
The above information is edited by the chemicalbook of Tian Ye.
Chemical PropertiesYellow Solid
UsesNifuratel is a drug used as an antibacterial, antifungal, antiprotozoal (Trichomonas). Nifuratel appears to have a broad antibacterial spectrum of action and is effective against Chlamydia trachomatis and Mycoplasma spp. as well as fungal infections from Candida spp.
Brand nameMacmiror (Polichimica Sap, Italy); Magmilor (Polichimica Sap, Italy); Polmiror (Polichimica Sap, Italy); Tydantil (Polichimica Sap, Italy).
Pharmaceutical ApplicationsA synthetic compound available as tablets and vaginal preparations. It is poorly soluble in water, but readily soluble in dimethylformamide.
The activity is similar to that of nitrofurantoin but it is more active, especially against Gram-negative anaerobes. It also has modest, but clinically useful, activity against Candida albicans. Little is known about the pharmacokinetics. It structurally resembles furazolidone, and may undergo a similar degree of metabolism. It does not achieve therapeutic concentrations in the bloodstream after oral administration and it seems likely that the antibacterial activity in urine is due to active metabolites. There is little or no systemic absorption when vaginal suppositories are used.
As with other members of the group, side effects are mostly associated with the upper gastrointestinal tract. It is used to treat urinary infections and vaginal candidiasis.
Nifuratel Preparation Products And Raw materials
Tag:Nifuratel(4936-47-4) Related Product Information
Nifuratel Impurity 4 Nifuratel Impurity 1-hydrazino-3-(methylthio)propan-2-ol 1-METHYLTHIO-2,3-EPOXYPROPANE 2-Furoic acid 2-Oxazolidone Ethyl carbazate 5-Methyloxazolidin-2-one Furazolidone Methyl carbazate 3-AMINO-2-OXAZOLIDINONE 2-FURALDEHYDE DIMETHYLHYDRAZONE hydrazinecarboxylic acid Furmethoxadon N-n-propyl-N-formylhydrazine 5-NITRO-2-METHYLFURAN 2-NITROFURAN Nifuratel