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Voriconazole

Voriconazole Suppliers list
Company Name: Capot Chemical Co.,Ltd.
Tel: +86 (0)571-855 867 18
Email: sales@capotchem.com
Products Intro: Product Name:(2R,3S)-2-(2,4-difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol
CAS:137234-62-9
Purity:98%(Min,HPLC) Package:100g;1kg;5kg,10kg,25kg,50kg
Company Name: Henan DaKen Chemical CO.,LTD.
Tel: +86-371-55531817
Email: inquiry@dakenchem.com
Products Intro: Product Name:Voriconazole
CAS:137234-62-9
Purity:99% Package:100g,500g,1KG,10KG,100KG
Company Name: Beijing Cooperate Pharmaceutical Co.,Ltd.
Tel: +86-10-60279497 +86(0)15646567669
Email: sales01@cooperate-pharm.com
Products Intro: Product Name:Voriconazole
CAS:137234-62-9
Purity:98% Package:100G;1KG;50KG;100KG;1000KG
Company Name: Henan Tianfu Chemical Co.,Ltd.
Tel: 0371-55170693
Email: info@tianfuchem.com
Products Intro: Product Name:Voriconazole
CAS:137234-62-9
Purity:99% Package:500G;1KG;5KG;25KG
Company Name: Mainchem Co., Ltd.
Tel: +86-0592-6210733
Email: sales@mainchem.com
Products Intro: Product Name:Voriconazole
CAS:137234-62-9

Lastest Price from Voriconazole manufacturers

  • VORICONAZOLE
  • US $10.00 / KG
  • 2018-09-26
  • CAS:137234-62-9
  • Min. Order: 10G
  • Purity: 99%
  • Supply Ability: 10MT
  • Voriconazole
  • US $10.00 / KG
  • 2018-09-17
  • CAS:137234-62-9
  • Min. Order: 10G
  • Purity: 99%
  • Supply Ability: 500kg/month
  • Voriconazole
  • US $1.00 / KG
  • 2018-08-21
  • CAS:137234-62-9
  • Min. Order: 1KG
  • Purity: 98%
  • Supply Ability: 100KG
Voriconazole Basic information
Product description Pharmacological interactions Uses
Product Name:Voriconazole
Synonyms:Voriconazole 2-(2,4-Difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol;Voriconazole solution;(2R,3S)-2-(2,4-Difluorophenyl)-3;2-(2,4-difluorophenyl)-3-(5-fluoro-4-pyrimidinyl)-1-(1,2,4-triazol-1-yl)butan-2-ol;2-(2,4-difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1,2,4-triazol-1-yl)butan-2-ol;Voriconazole, >=98.5%;(2R,3S)-2-(2,4-Difluorophenyl)-3-(5-fluoro-4-pyrimidinyl)-1-((1H)-1,2,4-triazol-1-yl)-butan-2-;Voriconazole≥ 99.9% (HPLC, Dried basis)
CAS:137234-62-9
MF:C16H14F3N5O
MW:349.31
EINECS:200-261-5
Product Categories:Fine Chemical;antifungal;API;Antifungal (Systemic);Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;Aromatics;Heterocycles;Pfizer compounds;Inhibitor;ZINACEF
Mol File:137234-62-9.mol
Voriconazole Structure
Voriconazole Chemical Properties
Melting point 127-130°C
alpha D25 -62° (c = 1 in methanol)
Fp 9℃
storage temp. Store at +4°C
solubility DMSO: >20mg/mL
Merck 14,10033
InChIKeyBCEHBSKCWLPMDN-MGPLVRAMSA-N
CAS DataBase Reference137234-62-9(CAS DataBase Reference)
Safety Information
Hazard Codes Xn,T,F
Risk Statements 22-36/38-52/53-48/22-40-25-61-39/23/24/25-23/24/25-11
Safety Statements 26-36-45-36/37-22-53-16
RIDADR UN1230 - class 3 - PG 2 - Methanol, solution
RTECS UV9145000
HazardClass 6.1
PackingGroup III
MSDS Information
Voriconazole Usage And Synthesis
Product description Voriconazole is a broad-spectrum triazole antifungal ,it is primarily used for the treatment of progressive, possibly life-threatening infections in immune deficiency patients. Indications include: immunosuppressed patients with severe fungal infections, acute invasive aspergillosis (the most common pathogen is Aspergillus fumigatus, followed by A. flavus, Aspergillus niger and Aspergillus soil), severe invasive infections caused by fluconazole-resistant Candida (including C. krusei) severe infection caused by Foot actinomycetes bacteria genus and Fusarium bacteria genus . Moderate to severe renal insufficiency is administered intravenously paying caution.
Pharmacological interactionsCombination With the CYP3A4 substrates, terfenadine, sirolimus, astemizole, cisapride, pimozide or quinidine , can increase blood concentrations of this drug, leading to QT prolongation, and occasionally torsades de pointes ventricular tachycardia.
Combination With Rifampicin, rifabutin, efavirenz, ritonavir (each 400mg, once every 12 hours), carbamazepine and phenobarbital, can significantly lower blood concentrations of voriconazole.
Combination with ergot alkaloids (ergotamine, dihydroergotamine) plasma concentrations of ergot drugs can cause increased ergot poisoning.
The above information is edited by the chemicalbook of Tian Ye.
Usesbroad-spectrum antifungal
Chemical PropertiesCyrstalline Solid
UsesAn antifungal (systemic). An ergosterol biosynthesis inhibitor.
Usesantibacterial
UsesAn antifungal. An Ergosterol Biosynthesis inhibitor
DefinitionChEBI: A triazole-based antifungal agent used for the treatment of esophageal candidiasis, invasive pulmonary aspergillosis, and serious fungal infections caused by Scedosporium apiospermum and Fusarium spp. It is an inhibitor of cytochr me P450 2C9 (CYP2C9) and CYP3A4.
UsesVoriconazole is a triazole, antifungal agent that inhibits a broad range of pathogenic yeasts, including Candida (MIC = 0.03-8 μg/ml), and filamentous fungi such as Aspergillus, Scedosporium, and Fusarium. Its inhibitory action results from its ability to inhibit the synthesis of ergosterol, the major sterol of the fungal cell membrane.
Brand nameVfend (Pfizer).
Biological ActivityTriazole antifungal agent. Displays potent activity against Candida , Cryptococcus and Aspergillus species.
Voriconazole Preparation Products And Raw materials
Tag:Voriconazole(137234-62-9) Related Product Information
Itraconazole Ambroxol Ravuconazole Candesartan ALBUMIN, HUMAN Fluconazole DEXMEDETOMIDINE Linezolid Meropenem Tigecycline (+)-Griseofulvin Ceftriaxone sodium Nystatin Clindamycin (2RS, 3RS)-2-(2,4-Difluorophenyl)-3-(5-fluoropyriMidin-4-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol) 5-Fluoropyrimidine Pyrimidine 6-ethyl-5-fluoropyrimidine-4(3H) one (intermediate of voriconazole)