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LDN212854

LDN212854 Suppliers list
Company Name: ATK CHEMICAL COMPANY LIMITED
Tel: +86 21 5161 9050/ 5187 7795
Email: ivan@atkchemical.com
Products Intro: Product Name:LDN-212854
Purity:98% HPLC Package:5MG;10MG;50MG;100MG,1G,5G
Company Name: Hubei xin bonus chemical co. LTD
Tel: 86-13657291602
Email: linda@hubeijusheng.com
Products Intro: Product Name:LDN212854
CAS:1432597-26-6
Purity:0.99 Package:5KG;1KG
Company Name: career henan chemical co
Tel: 0086-371-86658258
Email: factory@coreychem.com
Products Intro: Product Name:LDN212854
CAS:1432597-26-6
Purity:99% Package:1KG;1USD
Company Name: Target Molecule Corp
Tel: 781-999-5354
Email: marketing@targetmol.com
Products Intro: Product Name:LDN212854;BMP Inhibitor III
CAS:1432597-26-6
Purity:99.38% Package:1 mg;5 mg;10 mg;25 mg;50 mg;1 mL * 10 mM (in DMSO) Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: HANGZHOU CLAP TECHNOLOGY CO.,LTD
Tel: 86-571-88216897、88216896
Email: sales@hzclap.com
Products Intro: Product Name:LDN212854
CAS:1432597-26-6
Purity:99% Package:10kg 25kg 200 kilograms per barrel Remarks:good

Lastest Price from LDN212854 manufacturers

  • LDN212854
  • US $1.00 / KG
  • 2019-12-23
  • CAS:1432597-26-6
  • Min. Order: 1KG
  • Purity: 99%
  • Supply Ability: 100KG
LDN212854 Basic information
Description In vitro In vivo
Product Name:LDN212854
Synonyms:LDN212854;Quinoline, 5-[6-[4-(1-piperazinyl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]-;BMP Inhibitor III;5-[6-[4-(1-Piperazinyl)phenyl]pyrazolo[1,5-a]pyriMidin-3-yl]quinoline;CS-1202;BMP INHIBITOR III;LDN212854;LDN 212854;5-[6-[4-(1-Piperazinyl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]quinoline LDN 212854;LDN 212854 5-[6-[4-(1-Piperazinyl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]quinoline
CAS:1432597-26-6
MF:C25H22N6
MW:406.48
EINECS:808-898-3
Product Categories:Inhibitors
Mol File:1432597-26-6.mol
LDN212854 Structure
LDN212854 Chemical Properties
density 1.33±0.1 g/cm3(Predicted)
storage temp. 2-8°C
solubility DMSO: soluble1mg/mL, clear (warmed)
form powder
pka8.79±0.10(Predicted)
color white to beige
InChIKeyBBDGBGOVJPEFBT-UHFFFAOYSA-N
CAS DataBase Reference1432597-26-6
Safety Information
Hazard Codes Xn
Risk Statements 22
WGK Germany 3
MSDS Information
LDN212854 Usage And Synthesis
DescriptionLDN-212854 is a potent and selective BMP receptor inhibitor with IC50 of 1.3 nM for ALK2, about 2-, 66-, 1641-, and 7135-fold selectivity over ALK1, ALK3, ALK4, and ALK5, respectively.
In vitroIn myofibroblast C2C12 cells, LDN-212854 exhibits greater selectivity for BMP6-versus BMP4-induced osteogenic differentiation.
In vivoLDN-212854 (6 mg/kg, i.p.) effectively neutralize ALK2 signaling in vivo, and potently inhibits heterotopic ossification in an inducible transgenic mutant ALK2 mouse model of fibrodysplasia ossificans progressiva.
LDN212854 Preparation Products And Raw materials
Tag:LDN212854(1432597-26-6) Related Product Information
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