- 4-tert-Butylbenzyl bromide
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- $100.00 / 1KG
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2025-09-25
- CAS:18880-00-7
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: g-kg-tons, free sample is available
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| | 4-tert-Butylbenzyl bromide Basic information |
| | 4-tert-Butylbenzyl bromide Chemical Properties |
| Melting point | 8-12 °C (lit.) | | Boiling point | 93-94 °C/1.5 mmHg (lit.) | | density | 1.236 g/mL at 25 °C (lit.) | | refractive index | n20/D 1.545(lit.) | | Fp | >230 °F | | storage temp. | under inert gas (nitrogen or Argon) at 2-8°C | | solubility | Chloroform (Slightly), Ethyl Acetate (Slightly) | | form | Liquid | | color | Clear light yellow | | Specific Gravity | 1.236 | | BRN | 471674 | | InChI | InChI=1S/C11H15Br/c1-11(2,3)10-6-4-9(8-12)5-7-10/h4-7H,8H2,1-3H3 | | InChIKey | QZNQSIHCDAGZIA-UHFFFAOYSA-N | | SMILES | C1(CBr)=CC=C(C(C)(C)C)C=C1 | | CAS DataBase Reference | 18880-00-7(CAS DataBase Reference) | | NIST Chemistry Reference | p-tert-Butylbenzyl bromide(18880-00-7) |
| Hazard Codes | C,Xi | | Risk Statements | 34 | | Safety Statements | 26-36/37/39-45 | | RIDADR | UN 3265 8/PG 2 | | WGK Germany | 3 | | F | 19 | | HazardClass | 8 | | PackingGroup | II | | HS Code | 29036990 | | Storage Class | 8A - Combustible corrosive hazardous materials | | Hazard Classifications | Skin Corr. 1B |
| | 4-tert-Butylbenzyl bromide Usage And Synthesis |
| Chemical Properties | colorless to light yellow liquid | | Uses | 4-tert-Butylbenzyl bromide, a hydrophobic reactant, was used to keep the loaded mesoporous material particles under continuous stirring. | | General Description | The nucleophilic substitution reaction of 4-tert-butylbenzyl bromide and potassium iodide was carried out in oil-in-water microemulsions based on various surfactants. | | Synthesis | General procedure for the synthesis of 4-tert-butylbenzyl bromide from 4-tert-butyltoluene: Referring to Example 19 Preparation of N-(4-tert-butylbenzyl)methanamine (Alternative method), 4-tert-butyltoluene (14.8 g, 0.10 mol) was dissolved in carbon tetrachloride, and N-bromosuccinimide (17.8 g, 0.10 mol) and benzoyl peroxide (200 mg) were added . The reaction mixture was refluxed for 2 h and subsequently cooled to room temperature. The insoluble material was removed by filtration and the filtrate was washed with carbon tetrachloride. The filtrate was concentrated under reduced pressure and the resulting residue was dissolved in hexane and dried with magnesium sulfate. Finally, the solvent was evaporated under reduced pressure to give 22.7 g of 4-tert-butylbenzyl bromide (yield: 100%). | | References | [1] Patent: US6586633, 2003, B1
[2] Patent: CN105315127, 2016, A. Location in patent: Paragraph 0044-0050
[3] Tetrahedron Letters, 2009, vol. 50, # 16, p. 1861 - 1865
[4] Synthesis, 2009, # 11, p. 1807 - 1810
[5] Synthetic Communications, 2010, vol. 40, # 7, p. 998 - 1003 |
| | 4-tert-Butylbenzyl bromide Preparation Products And Raw materials |
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