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ETHYLENE OXIDE

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Company Name: Hebei Guanlang Biotechnology Co., Ltd.
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Products Intro: Product Name:ETHYLENE OXIDE
CAS:75-21-8
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Company Name: Henan DaKen Chemical CO.,LTD.
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Products Intro: Product Name:ETHYLENE OXIDE
CAS:75-21-8
Purity:99% Package:100g,500g,1kg,5kg,10kg
Company Name: Henan Tianfu Chemical Co.,Ltd.
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Purity:99% Package:500G;1KG;5KG;25KG
Company Name: Mainchem Co., Ltd.
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Products Intro: Product Name:ETHYLENE OXIDE
CAS:75-21-8
Company Name: career henan chemical co
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Products Intro: Product Name:ETHYLENE OXIDE
CAS:75-21-8
Purity:99% Package:1kg;1USD

Lastest Price from ETHYLENE OXIDE manufacturers

  • ETHYLENE OXIDE
  • US $1.00 / kg
  • 2018-12-24
  • CAS:75-21-8
  • Min. Order: 1g
  • Purity: 99%
  • Supply Ability: 100KG
ETHYLENE OXIDE Basic information
Product Name:ETHYLENE OXIDE
Synonyms:ETHYLENE OXIDE, 99.5+%;ETHYLENE OXIDE CYLINDER WITH 2 L (NET ~1 .5 KG);ETHYLENE OXIDE, 1X1ML, MEOH, 50000UG/ML;ETHYLENE OXIDE 1X1ML, CH2CL2, 2000UG/ML;ETHYLENE OXIDE, CYLINDER WITH 27 L (NET ~20 KG);ETHYLENE OXIDE, 1X1ML, CH2CL2, 50000UG/M L;ETHYLENE OXIDE, PRESSURE TIN WITH 250 ML (NET ~225 G);ethylene oxide solution
CAS:75-21-8
MF:C2H4O
MW:44.05
EINECS:200-849-9
Product Categories:Organics;Oxiranes;Simple 3-Membered Ring Compounds;EQ - EZPesticides;FumigantsChromatography;General Use;Air Monitoring Standards;Alpha Sort;E;E-LAlphabetic;Insecticides;Volatiles/ Semivolatiles;Chemical Synthesis;Specialty Gases;Synthetic Reagents
Mol File:75-21-8.mol
ETHYLENE OXIDE Structure
ETHYLENE OXIDE Chemical Properties
Melting point −111 °C(lit.)
Boiling point 10.7 °C(lit.)
density 0.882 g/mL at 25 °C(lit.)
vapor pressure 1095 mmHg at 20 °C
refractive index n20/D 1.3597(lit.)
Fp <-17.7℃
storage temp. Refrigerator
OdorSweet odor detectable at 257 to 690 ppm
Merck 3802
BRN 102378
InChIKeyIAYPIBMASNFSPL-UHFFFAOYSA-N
CAS DataBase Reference75-21-8(CAS DataBase Reference)
Safety Information
Hazard Codes F+,T,F
Risk Statements 45-46-12-23-36/37/38-39/23/24/25-23/24/25-11-67-20-36/37-19-6
Safety Statements 53-45-36/37-16-24/25-23-26
RIDADR UN 2037 2.3
WGK Germany 2
RTECS KX2450000
4.5-31
Autoignition Temperature429 °C
HazardClass 2.3
HS Code 29101000
ToxicityLD50 oral (rat) 72 mg/kg
LC50 inhal (rat) 800 ppm (1600 mg/m3)
PEL (OSHA) 1 ppm (2 mg/m3)
TLV-TWA (ACGIH) 1 ppm (2 mg/m3)
MSDS Information
ProviderLanguage
SigmaAldrich English
ETHYLENE OXIDE Usage And Synthesis
DescriptionEthylene oxide (C2H4O) is a kind of cyclic ether with important industrial applications. Although it is highly toxic and dangerous for household application and consumers to use, it can be used for the manufacture of many important industrial and commercialized products as well as some chemicals and intermediates. For example, it is very useful in the production of detergents, thickeners, solvents, plastics, and many kinds of organic chemicals such as ethylene glycol, ethanolamines, simple and complex glycols, polyglycol ethers, and other compounds. It is also a commonly sterilization methods used in the healthcare industry. In addition, it can be used as an accelerator of maturation of tobacco leaves and fungicide, as well as the main component of thermobaric weapons (fuel-air explosives). In industry, it is generally manufactured through direct oxidation of ethylene. In low doses, it can be used as a pesticide and a sterilizing agent owing to its effect of causing DNA damage. However, this property also make it a potential carcinogen.
Chemical PropertiesEthylene oxide is the simplest cyclic ether. It is a colorless gas or liquid and has a sweet, etheric odor. Ethylene oxide is a flammable, very reactive and explosive chemical substance. On decomposition, vapors of pure ethylene oxide mix with air or inert gases and become highly explosive. Ethylene oxide, is used in large scale as an intermediate in the production of monoethylene glycol, diethylene glycol, triethylene glycol, poly(ethylene) glycols, ethylene glycol ethers, ethanolamine, ethoxylation products of fatty alcohols, fatty amines, alkyl phenols, cellulose, and poly(propylene glycol). It is also used as a fumigant for food and cosmetics, and in hospital sterilization of surgical equipment and heat sensitive materials.
Chemical PropertiesEthylene oxide is the simplest cyclic ether. It is a colourless gas or liquid and has a sweet, etheric odour. Etylene oxide is a flammable and very reactive and explosive chemical substance. On decomposition, vapours of pure ethylene oxide mix with air or inert gases and become highly explosive. Industrial use of ethylene oxide is extensive, as an intermediate in the production of monoethylene glycol, diethylene glycol, triethylene glycol, poly(ethylene) glycols, ethylene glycol ethers, ethanolamine, ethoxylation products of fatty alcohols, fatty amines, alkyl phenols, cellulose, and poly(propylene glycol). It is also used as a fumigant fungicide and insecticide, in the sterilisation of surgical instruments/ equipments and heat-sensitive materials in the hospital, in the sterilisation/fumigation of some imported foods, in the fumigation of books and archival materials in museums, and in the fumigation of furs, textiles, and furniture.
Chemical PropertiesEthylene oxide is a colorless, compressed, liquefied gas or liquid (below 11℃). Sweet odor; the odor threshold is 50 ppm.
UsesFumigant for foodstuffs and textiles; to sterilize surgical instruments; agricultural fungicide. In organic syntheses, especially in the production of ethylene glycol. Starting material for the manufacture of acrylonitrile and nonionic surfactants.
DefinitionChEBI: A saturated organic heteromonocyclic parent that is a three-membered heterocycle of two carbon atoms and one oxygen atom.
General DescriptionA clear colorless gas with an ethereal odor. Flash point below 0°F. May polymerize exothermically if heated or contaminated. If the polymerization takes place inside a container, the container may rupture violently. Vapors may burn inside a container. Vapors irritate the eyes, skin, and respiratory system. Prolonged skin contact may result in delayed burns. Less dense than water. Vapors heavier than air. Vapors very toxic. Under prolonged exposure to fire or heat the containers may rupture violently and rocket. Used to make other chemicals, as a fumigant and industrial sterilant (AAR, 1999).
Air & Water ReactionsHighly flammable. Flammable over a wide vapor-air concentration range. Must be diluted on the order of 24 to 1 with water to lose flammability. Soluble in water.
Reactivity ProfileColorless gas at room temperature (b.p. 11°C), confirmed carcinogen. Highly flammable, severe explosion hazard when exposed to flame. The autoignition temperature may be as low as 140° C in presence of rust. Rapid compression of the vapor with air causes explosion. ETHYLENE OXIDE vapor may be initiated into explosive decomposition in absence of air [Hess, L. G., et al., Ind. Eng. Chem., 1950, 42, p. 1251]. Metal fittings containing magnesium, copper or silver should be avoided, since traces of acetylene in ETHYLENE OXIDE may produce metal acetylides capable of detonating the vapor [MCA SD-38, 1971]. Violent polymerization occurs on contact with strong bases (alkali hydroxides, ammonia) or acids, amines, metallic potassium, oxides (aluminum oxide, iron oxide, rust), covalent halides (aluminum chloride, ferric chloride, tin(IV) chloride) [Gupta, A. K., J. Soc. Chem. Ind., 1949, 68, p. 179]. Violent reaction with m-nitroaniline, magnesium perchlorate, mercaptans, thiols, triethylamine [Bretherick, 5th ed., 1995, p. 316]. ETHYLENE OXIDE and SO2 can react violently in pyridine solution with pressurization if ETHYLENE OXIDE is in excess (Nolan, 1983, Case History 51).
HazardIrritant to eyes and skin. Confirmed carcinogen. Highly flammable, dangerous fire and explosion risk, flammable limits in air 3–100%.
Health HazardEthylene oxide is toxic by inhalation. Symptoms of overexposure include headache, dizziness, lethargy, behavioral disturbances, weakness, cyanosis, loss of sensation in the extremities, reduction in the sense of smell and/or taste, progressing with increasing exposure to convulsions, seizure and coma. Ethylene oxide is also an irritant to the skin and the respiratory tract, and inhaling the vapors may cause the lungs to fi ll with fl uid several hours after exposure. Inhalation may cause dizziness or drowsiness. Liquid contact may cause frostbite, and an allergic skin reaction. After oral exposure (ingestion) to ethylene oxide, laboratory animals show adverse effects in the blood, damage to the liver, kidneys, reproductive effects, miscarriages/spontaneous abortion, and cancer
Health HazardETHYLENE OXIDE can cause death. Lowest inhalation concentration causing toxic effects is 12500 ppm/10 seconds. It is a strong skin irritant. Neurological disorders and even death have been reported.
Health HazardEthylene oxide is a severe irritant to the eyes, skin, and respiratory tract and exhibits moderate acute toxicity by all routes of exposure. Symptoms of overexposure by inhalation may be delayed and can include nausea, vomiting, headache, drowsiness, and difficulty breathing. Ethylene oxide can cause serious burns to the skin, which may only appear after a delay of 1 to 5 hours. This substance may also be absorbed through the skin to cause the systemic effects listed above. Eye contact can result in severe burns. Ethylene oxide is not considered to have adequate warning properties. Ethylene oxide is listed by IARC in Group 2A ("probable human carcinogen") and is classified as a "select carcinogen" under the criteria of the OSHA Laboratory Standard. There is some evidence from animal studies that ethylene oxide may be a developmental and reproductive toxin in both males and females. Exposure to this substance may lead to sensitization.
Fire HazardEthylene oxide is an extremely flammable substance (NFPA rating = 4). Ethylene oxide vapor may be ignited by hot surfaces such as hot plates and static electricity discharges, and since the vapor is heavier than air, it may travel a considerable distance to an ignition source and flash back. Ethylene oxide vapor forms explosive mixtures with air at concentrations of 3 to 100% (by volume). Carbon dioxide or dry chemical extinguishers should be used for ethylene oxide fires. Ethylene oxide may explode when heated in a closed vessel.
Fire HazardSevere explosion hazard when exposed to heat or flame. Irritating vapors are generated when heated. Vapor is heavier than air and may travel considerable distance to a source of ignition and flash back. Vapor forms explosive mixtures with air over a wide range. Liquid is not detonable but the vapor may be readily initiated into explosive decomposition. Avoid metal fittings containing copper, silver, mercury or magnesium; ammonia, oxidizing agents; acids, organic bases; amines; certain salts; alcohols; mercaptans, ferric chloride; magnesium perchlorate; m-nitroaniline; trimethylamine, potassium, tin chlorides; alkanethiols; bromoethane; aluminum chloride; aluminum oxide; iron chlorides; and iron oxides. Avoid air, heat, acids and bases, metal or metal chloride catalysts. Hazardous polymerization may occur. Avoid acids; covalent halides such as chlorides of aluminum, iron (III), tin (IV); basic materials like alkali hydrides, ammonia, amines, and potassium; catalytically active solids such as aluminum or iron oxides or rust, chlorides of boron, aluminum, tin, and iron; some carbonates; and metals such as copper and copper alloys
Agricultural UsesFungicide and fumigant: Ethylene oxide is used as a fumigant for spices, seasonings, and foodstuffs and as an agricultural fungicide. When used directly in the gaseous form or in nonexplosive gaseous mixtures with nitrogen or carbon dioxide, ethylene oxide can act as a disinfectant, fumigant, sterilizing agent, and insecticide. It is a man-made chemical used as an intermediate in organic synthesis for ethylene glycol, polyglycols, glycol ethers, esters, ethanolamines, acrylonitrile, plastics, and surface-active agents. It is also used as a fumigant for textiles and for sterilization, especially for surgical instruments. It is used in drug synthesis and as a pesticide intermediate. Not approved for use in EU countries. Actively registered in the U.S.
Trade nameAMPROLENE®; ANPROLENE®; ANPROLINE®; BIODAC®; MERPOL®; OXYFUME®; OXYFUME 12®; T-GAS®; STERILIZING GAS ETHYLENE OXIDE 100%®
Contact allergensEthylene oxide is a very strong irritant widely used in the chemical industry, and as a sterilizer of medical supplies, pharmaceutical products, and food. It can produce immediate (urticaria, asthma, anaphylaxis) or delayed reactions (irritant rather than allergic contact dermatitis). For example, residues in masks or dressings can produce irritant contact dermatitis.In delayed contact allergy, it seems that cross-reaction can be observed to epichlorhydrin or epoxypropane
Safety ProfileConfirmed human carcinogen with experimental carcinogenic, tumorigenic, neoplastigenic, and teratogenic data. Poison by ingestion, intraperitoneal, subcutaneous, and intravenous routes. Moderately toxic by inhalation. Human systemic effects by inhalation: convulsions, nausea, vomiting, olfactory and pulmonary changes. Experimental reproductive effects. Mutation data reported. A skin and eye irritant. An irritant to mucous membranes of respiratory tract. High concentrations can cause pulmonary edema. Highly flammable liquid or gas. Severe explosion hazard when exposed to flame. To fight fire, use alcohol foam, CO2, dry chemical. Violent polymerization occurs on contact with ammonia, alkali hydroxides, amines, metalllc potassium, acids, covalent halides (e.g., aluminum chloride, iron(Ⅲ) chloride, tin(rv> chloride, aluminum oxide, iron oxide, rust). Explosive reaction with glycerol at 200℃. Rapid compression of the vapor with air causes explosions. Incompatible with bases, alcohols, air, m-nitroanlline, trimethyl amine, copper, iron chlorides, iron oxides, magnesium perchlorate, mercaptans, potassium, tin chlorides, contaminants, alkane thols, bromoethane. When heated to decomposition it emits acrid smoke and irritating fumes.
Potential ExposureEthylene oxide is a man-made chemical used in the production of glycols (ethylene glycol, polyglycols, glycol ethers, esters), nontonic surface-active agent; ethanolamines, acrylonitrile, plastics. It is also used as a fumigant for foodstuffs and textiles; an agricultural fungicide; and for sterilization, especially for surgical instruments. It is used in drug synthesis and as a pesticide intermediate
First aidIf ethylene oxide gets into the eyes, remove any contact lenses at once and irrigate immediately for at least 15 minutes, occasionally lifting upper and lower lids. Seek medical attention immediately. If this chemical contacts the skin, remove contaminated clothing and wash immediately with soap and water. Seek medical attention immediately. If this chemical has been inhaled, remove from exposure, begin rescue breathing (using universal precautions, including resuscitation mask) if breathing has stopped and CPR if heart action has stopped. Transfer promptly to a medical facility. When this chemical has been swallowed, get medical attention. Give large quantities of water and induce vomiting. Do not make an unconscious person vomit. If frostbite has occurred, seek medical attention immediately; do NOT rub the affected areas or flush them with water. In order to prevent further tissue damage, do NOT attempt to remove frozen clothing from frostbitten areas. If frostbite has NOT occurred, immediately and thoroughly wash contaminated skin with soap and water. Medical observation is recommended for 24 to 48 hours after breathing overexposure, as pulmonary edema may be delayed. As first aid for pulmonary edema, a doctor or authorized paramedic may consider administering a drug or other inhalation therapy.
storagework with ethylene oxide should be conducted in a fume hood to prevent exposure by inhalation, and appropriate impermeable gloves and splash goggles should be worn at all times to prevent skin and eye contact. Ethylene oxide should be used only in areas free of ignition sources and should be stored in the cold in tightly sealed containers placed within a secondary container.
ShippingUN1040 Ethylene oxide or Ethylene oxide with nitrogen up to a total pressure of 1 MPa (10 bar) at 50℃, Hazard Class: 2.3; Labels: 2.3-Poisonous gas, 2.1- Flammable gas, Inhalation Hazard Zone D. Cylinders must be transported in a secure upright position, in a wellventilated truck. Protect cylinder and labels from physical damage. The owner of the compressed gas cylinder is the only entity allowed by federal law (49CFR) to transport and refill them. It is a violation of transportation regulations to refill compressed gas cylinders without the express written permission of the owner
Purification MethodsDry oxirane with CaSO4, then distil it from crushed NaOH. It has also been purified by passage, as a gas, through towers containing solid NaOH. [Beilstein 17/1 V 3.]
Flammability and ExplosibilityEthylene oxide is an extremely flammable substance (NFPA rating = 4). Ethylene oxide vapor may be ignited by hot surfaces such as hot plates and static electricity discharges, and since the vapor is heavier than air, it may travel a considerable distance to an ignition source and flash back. Ethylene oxide vapor forms explosive mixtures with air at concentrations of 3 to 100% (by volume). Carbon dioxide or dry chemical extinguishers should be used for ethylene oxide fires. Ethylene oxide may explode when heated in a closed vessel.
IncompatibilitiesMay form explosive mixture with air. Chemically unstable. Dangerously reactive; may rearrange chemically and/or polymerize violently with evolution of heat; when in contact with highly active catalytic surfaces, such as anhydrous chlorides of iron, tin and aluminum; pure oxides of iron and aluminum; and alkali metal hydroxides. Even small amounts of strong acids; alkalis, or oxidizers can cause a reaction. Avoid contact with copper. Protect container from physical damage, sun and heat. Attacks some plastics, rubber or coatings.
Waste DisposalReturn refillable compressed gas cylinders to supplier. Concentrated waste containing no peroxides-discharge liquid at a controlled rate near a pilot flame. Concentrated waste containing peroxides-perforation of a container of the waste from a safe distance followed by open burning
PrecautionsEthylene oxide is dangerously explosive under fi re condition; it is flammable over an extremely large range of concentrations in air and burns in the absence of oxygen.
Referenceshttps://en.wikipedia.org/wiki/Ethylene_oxide
https://www.cancer.gov/about-cancer/causes-prevention/risk/substances/ethylene-oxide
ETHYLENE OXIDE Preparation Products And Raw materials
Preparation ProductsTRIETHYLENE GLYCOL MONOMETHYL ETHER-->Dipropylene glycol monomethyl ether-->Polyethylene glycol monooleate -->pesticide emulsifier BCL-->POLYETHYLENE GLYCOL MONOOLEYL ETHER-->antistatic agent F695-->leveler AC-->Antistatic agent SN-->Tween 85-->demulsifier DQ125 series-->emulsifier SOPE-15-->ETHOXYLATEDMONO-ANDDI-GLYCERIDES-->ning emulsifier 33^<#^>-->Antifoaming agent PPE-->C^{12~18^} fatty alcohol polyoxyethylene (35) ether-->additive AC1210-->Bis[2-(2-hydroxyethoxy)ethyl] ether-->2-(2-Chloroethoxy)ethanol-->Dispersing agent IW-->Tween 20 -->Fatty alcohol polyoxyethylene ether O-15-->C^{8~9^} alkyl phenyl polyoxyethylene (13) ether-->defoaming agent BAPE-->C^{12~18^} fatty alcohol polyoxyethylene (15) ether-->emulsifier SOPE-10-->TRIS(2-CHLOROETHYL) PHOSPHITE-->2-PROPOXYETHANOL-->C^{10~18^} fatty alcohol polyoxyethylene (9) ether-->Emulsifier (S-185)-->Sodium isethionate-->C^{8~9^} alkyl phenyl polyoxyethylene (14) ether-->demulsifire N-220 series-->demulsifier TA1031-->nonyl phenyl polyoxyethylene (9) ether-->2-Anilinoethanol-->Fatty amine polyoxyethylene ether-->polyoxyethlene glycerine ether monostearate
Raw materialsEtanol-->Nitrogen-->Chlorine-->Oxygen-->Calcium oxide-->2-Chloroethanol-->Silicon carbide-->Alkali Metals, plasma standard solution, Specpure, Ba,Be,Ca,Cs,K,Li,Mg,Na,Rb,Sr, 100μg/ml-->ETHYLENE-->PETROLEUM ETHER-->Silver catalyst-->Alkaline Earth Metals, plasma standard solution, Specpure, Ba, Be, Ca, Mg, Sr § 100μg/ml
Tag:ETHYLENE OXIDE(75-21-8) Related Product Information
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