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JOSAMYCIN

JOSAMYCIN Suppliers list
Company Name: Henan Tianfu Chemical Co.,Ltd.
Tel: 0371-55170693
Email: info@tianfuchem.com
Products Intro: Product Name:16846-24-5
CAS:16846-24-5
Purity:0.99 Package:25KG,5KG;1KG;500G
Company Name: career henan chemical co
Tel: +86-371-86658258
Email: sales@coreychem.com
Products Intro: Product Name:JOSAMYCIN
CAS:16846-24-5
Purity:95%-99% Package:1kg;1USD
Company Name: Chemwill Asia Co.,Ltd.
Tel: 86-21-51086038
Email: chemwill_asia@126.com;sales@chemwill.com;chemwill@hotmail.com;chemwill@gmail.com
Products Intro: CAS:16846-24-5
Purity:99% Package:5KG;1KG;25KG PRICE quotation Remarks:Factory stock, quality assurance, price concessions
Company Name: BOC Sciences
Tel: 1-631-619-7922
Email: inquiry@bocsci.com
Products Intro: Product Name:LEUCOMYCIN V,3-ACETA 4β-(3-METHYL BUTANOATE)
CAS:16846-24-5
Purity:95%
Company Name: Chongqing Chemdad Co., Ltd
Tel: +86-13650506873
Email: sales@chemdad.com
Products Intro: Product Name:JOSAMYCIN
CAS:16846-24-5
Purity:0.98 Package:1kg,2kg,5kg,10kg,25kg

Lastest Price from JOSAMYCIN manufacturers

  • JOSAMYCIN
  • US $1.00 / kg
  • 2019-07-06
  • CAS:16846-24-5
  • Min. Order: 1kg
  • Purity: 95%-99%
  • Supply Ability: 1000kg
JOSAMYCIN Basic information
Product Name:JOSAMYCIN
Synonyms:LEUCOMYCIN V,3-ACETA 4β-(3-METHYL BUTANOATE);Vilprafen;Wilprafen;Leucomycin V 3-acetate 4''-(3-methylbutanoate);YL-704A3;3-acetate4(supb)-(3-methylbutanoate);antibioticyl-704a3;kitasamycina3
CAS:16846-24-5
MF:C42H69NO15
MW:827.99
EINECS:240-871-6
Product Categories:Antibiotic Explorer;A - KAntibiotics;Antibacterial;Antibiotics A to;Antibiotics G-MAntibiotics;Chemical Structure Class;Interferes with Protein SynthesisAntibiotics;Macrolides;Mechanism of Action;Spectrum of Activity;Amines;Chiral Reagents;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals
Mol File:16846-24-5.mol
JOSAMYCIN Structure
JOSAMYCIN Chemical Properties
Melting point 131.5℃
alpha D25 -70° (c = 1 in ethanol)
Boiling point 763.27°C (rough estimate)
density 1.1547 (rough estimate)
refractive index 1.6220 (estimate)
storage temp. 2-8°C
solubility Soluble in ethanol
form powder
pka7.1 (40% aq methanol)
color white to slightly yellow
Merck 13,5286
Safety Information
WGK Germany 2
RTECS OH4725810
10
ToxicityLD50 oral in rat: > 7gm/kg
MSDS Information
ProviderLanguage
SigmaAldrich English
JOSAMYCIN Usage And Synthesis
Chemical PropertiesWhite or slightly yellowish powder, slightly hygroscopic.
UsesAs a 16-membered ring macrolide antibiotic with antimicrobial activity against a wide range of pathogens. Josamycin can be particularly used in the treatment of Mycoplasma infection.
DefinitionChEBI: A macrolide antibiotic produced by certain strains of Streptomyces narbonensis var. josamyceticus.
Pharmaceutical ApplicationsA naturally occurring antibiotic produced by Streptomyces narbonensis var. josamyceticus and belonging to the leucomycin group of macrolides. It is formulated for oral administration.
Many Gram-positive and Gram-negative anaerobes are susceptible, including Peptostreptococcus spp., Propionibacterium spp., Eubacterium spp. and Bacteroides spp.
After a single 1 g oral dose, a peak serum concentration of 2.74 mg/L was achieved 0.75 h after dosing. The AUC was 4.2 mg.h/L, and the apparent elimination half-life 1.5 h. Several inactive metabolites could be detected. It penetrates into saliva, tears and sweat, and achieves high levels in bile and lungs. It is mostly metabolized and excreted in the bile in an inactive form. Less than 20% of the dose appears in the urine, producing levels of around 50 mg/L.
The drug is generally well tolerated, producing only mild gastrointestinal disturbance. Its uses are similar to those of erythromycin. It is of limited availability.
JOSAMYCIN Preparation Products And Raw materials
Tag:JOSAMYCIN(16846-24-5) Related Product Information
DL-CARNITINE Josamycin 2',9-dipropionate,Josamycin 9,2'-dipropionate,Josamycin dipropionate JOSAMYCIN EPY(CRM STANDARD) JOSAMYCIN PROPIONATE EPY(CRM STANDARD) JOSAMYCIN MM(CRM STANDARD) JOSAMYCIN PROPIONATE Deisovaleryl josamycin E,E-8,10-DODECADIEN-1-YL ACETATE 4-(Dimethylamino)tetrahydro-2H-pyran 2-Ethylhexyloxypropylamine JOSAMYCIN methyl 3-(acetoxy)octanoate 8,10-DODECADIEN-1-OL ISO-PROPYL-UNDECYLENATE ETHYL 3 ACETOXY HEXANOATE DL-3-ACETOXYBUTYRIC ACID ETHYL ESTER