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| 1-Adamantanemethylamine Basic information |
| 1-Adamantanemethylamine Chemical Properties |
Boiling point | 83-85 °C/0.3 mmHg (lit.) | density | 0.933 g/mL at 25 °C (lit.) | refractive index | n20/D 1.5137(lit.) | Fp | 198 °F | storage temp. | 2-8°C(protect from light) | form | Liquid | pka | 10.71±0.29(Predicted) | color | Colorless to pale yellow | Sensitive | Air Sensitive | CAS DataBase Reference | 17768-41-1(CAS DataBase Reference) | NIST Chemistry Reference | 1-Adamantanemethylamine(17768-41-1) |
Hazard Codes | Xi,C | Risk Statements | 34 | Safety Statements | 24/25-45-36/37/39-27-26 | RIDADR | UN 2735 | WGK Germany | 3 | HazardClass | IRRITANT | HazardClass | 8 | HS Code | 29213000 |
| 1-Adamantanemethylamine Usage And Synthesis |
Chemical Properties | clear colourless to very slightly yellow liquid | Uses | Adamantan-1-ylmethanamine (1-Aminomethyladamantane) is a Hyt hydrophobic group. Adamantan-1-ylmethanamine can be used in the synthesis of ZX782 (HY-161972)[1]. | General Description | 1-Adamantanemethylamine is a large amine present on the wall of 6,7-diaminoquinoxaline. The thermodynamic complex formation constant of 1-adamantanemethylamine was studied. | Purification Methods | Dissolve the amine in Et2O, dry over KOH and distil it. The N-Tosyl derivative has m 134-135o (from EtOH). [Stetter & Goebel Chem Ber 96 550 1963.] | References | [1] Li X, et al. Design, Synthesis, and Biological Evaluation of Hydrophobic-Tagged Glutathione Peroxidase 4 (GPX4) Degraders. Bioorg Chem. 2024 Mar;144:107115. DOI:10.1016/j.bioorg.2024.107115 |
| 1-Adamantanemethylamine Preparation Products And Raw materials |
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