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Profenofos

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Company Name: ATK CHEMICAL COMPANY LIMITED
Tel: +86 21 5161 9050/ 5187 7795
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Products Intro: CAS:41198-08-7
Purity:98% HPLC Package:5G;10G;25G;50G;100G;250G;1KG
Company Name: career henan chemical co
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Products Intro: Product Name:Profenofos
CAS: 41198-08-7
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Company Name: Hubei Jusheng Technology Co.,Ltd.
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Products Intro: Product Name:profenofos
CAS:41198-08-7
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Products Intro: Product Name:Probromophosphorus crude oil
CAS:41198-08-7
Company Name: Shandong chuangyingchemical Co., Ltd.
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Products Intro: Product Name:Profenofos
CAS:41198-08-7

Lastest Price from Profenofos manufacturers

  • Profenofos EC
  • US $0.00 / Kg/Bag
  • 2021-06-17
  • CAS:
  • Min. Order: 1Kg/Bag
  • Purity: 99%
  • Supply Ability: 20ton
  • Profenofos
  • US $63.00 / KG
  • 2021-06-17
  • CAS:41198-08-7
  • Min. Order: 25KG
  • Purity: 99.99%
  • Supply Ability: 200ton
  • Profenofos
  • US $8.00 / Kg/Bag
  • 2020-11-16
  • CAS:41198-08-7
  • Min. Order: 1Kg/Bag
  • Purity: 99%
  • Supply Ability: 20 Tons
Profenofos Basic information
Product Name:Profenofos
Synonyms:cga15324;Polycron E.C.;Profenofos E.C.;O-(4-bromo-2-chlorophenyl) O-ethyl S-propyl phosphorothioate profenofos (ISO);CGA 15324S;4-Bromo-2-chloro-1-(ethoxy-propylsulfanylphosphoryl)oxybenzene;O-Ethyl S-propyl O-(2-chloro-4-bromophenyl)thiophosphate;O-Ethyl-S-n-propyl-O-(2-chloro-4-bromophenyl)thiophosphate
CAS:41198-08-7
MF:C11H15BrClO3PS
MW:373.63
EINECS:255-255-2
Product Categories:NULL;Agro-Products;Aromatics;Intermediates & Fine Chemicals;Pharmaceuticals;Phosphorylating and Phosphitylating Agents;Insecticides;Oeko-Tex Standard 100;OrganophorousMethod Specific;P;Alpha sort;N-PPesticides;Pesticides&Metabolites;Sulfur & Selenium Compounds;INSECTICIDE;Pesticides;PesticidesAlphabetic;PON - PT
Mol File:41198-08-7.mol
Profenofos Structure
Profenofos Chemical Properties
Melting point <25 °C
Boiling point 110°C (0.001 torr)
density d20 1.455
vapor pressure  1.24×10-4 Pa (25 °C)
refractive index n20D 1.5466
Fp 124℃
storage temp. APPROX 4°C
form Oily Liquid
Water Solubility  28 mg l-1 (25 °C)
Specific Gravity1.455 (20℃)
Merck 13,7860
BRN 2150258
CAS DataBase Reference41198-08-7(CAS DataBase Reference)
NIST Chemistry ReferencePhosphorothioic acid, o-(4-bromo-2-chlorophenyl) o-ethyl s-propyl ester(41198-08-7)
EPA Substance Registry SystemProfenofos (41198-08-7)
Safety Information
Hazard Codes Xn,N,T
Risk Statements 20/21/22-50/53-24-20/22-43
Safety Statements 36/37-60-61-45-9-7
RIDADR 3018
WGK Germany 3
RTECS TE6975000
HazardClass 6.1(b)
PackingGroup III
HS Code 29309090
Hazardous Substances Data41198-08-7(Hazardous Substances Data)
ToxicityLD50 in rat (mg/kg): 358-400 orally; ~3300 dermally; LC50 (4 hr) in rat (mg/m3): ~3000 by inhalation (Buholzer); LC50 (96 hr) in rainbow fish: 0.91 mg/l (Kumar, Chapman).
MSDS Information
Profenofos Usage And Synthesis
DescriptionProfenofos is a pale yellow liquid, bp 100 ?C/1.80 Pa, vp 0.124 mPa (25 ?C). Solubility in water is 28 mg/L (25 ?C). It is miscible with most organic solvents. Log Kow = 4.44. It is relatively stable in neutral and mild acid media but hydrolyzed in alkaline media; DT50 values (20 ?C) at pH 5, 7, and 9 are 93 d, 14.6 d, and 5.7 h, respectively.
Chemical PropertiesProfenofos is a pale yellow liquid. Profenofos is relatively stable under neutral and slightly acidic conditions and unstable under alkaline conditions.Profenofos has a garlic-like odor.
Profenofos has limited solubility in water (28 mg/L at 25°C) but is completely soluble in organic solvents (ethanol, acetone, toluene, n-octanol and n-hexane) at 25°C.
UsesA broad-spectrum organophosphorous pesticide that is used widely in cotton fields for insect control.
UsesInsecticide; acaricide.
UsesProfenofos is used to control insects (particularly caterpillars and Lepidoptera eggs) and mites on cotton, maize, sugar beet, soyabean, potatoes, vegetables, tobacco and a number of other crops
General DescriptionPale yellow liquid with garlic-like odor. Corrosive. Used as an insecticide.
Air & Water ReactionsHydrolyzed under alkaline conditions.
Reactivity ProfileOrganophosphates are susceptible to formation of highly toxic and flammable phosphine gas in the presence of strong reducing agents such as hydrides. Partial oxidation by oxidizing agents may result in the release of toxic phosphorus oxides.
Agricultural UsesProfenofos: Profenofos is A U.S. EPA restricted Use Pesticide (RUP) used solely on cotton to control a number of pests including tobacco budworm, cotton aphid and bollworm, armyworm, fleahopper and whiteflies. It is not registered for residential use. Not approved for use in EU countries. Registered for use in the U.S.
Trade nameCGA-15324®; CURACRON®; POLYCRON®; SELECRON®
CarcinogenicityIn a 2 year carcinogenicity study mice were given diets containing 0, 1, 30, or 100 ppm profenofos (equivalent to 0, 0.15, 4.5, or 15 mg/kg/day) for 85 weeks (males) or 97 weeks (females) . No treatment related clinical signs were observed. No treatment-related gross or microscopic lesions, tumors, or biologically significant differences in body weight or food consumption were observed between controls and profenofos-treated animals. Plasma and erythrocyte cholinesterase inhibition occurred at dose levels of 4.5 and 15 mg/kg/day. In another carcinogenicity study, rats were fed diets containing 0, 0.3, 10, or 100 ppm profenofos (equivalent to 0, 0.015, 0.5, or 5 mg/kg/day) for 2 years, and there was no increase in tumor incidence in any treated group compared to the control group .
Environmental FatePlant. Dislodgable residues of profenofos on cotton leaf 0, 24, 48, 72 and 96 hours after application (1.1 kg/ha) were 3.5, 1.1, 0.74, 0.51 and 0.35 μg/m2, respectively (Buck et al., 1980)
Photolytic. When profenofos in an aqueous buffer solution (pH 7.0) was exposed to filtered UV light (λ >290 nm) for 24 hours at 25 and 50°C, 29 and 61% respectively decomposed to 4-bromo-2-chlorophenol and 4-bromo-2-chlorophenyl ethyl hydrogen ph
Chemical/Physical. Emits toxic fumes of bromine, chlorine phosphorus and sulfur oxides when heated to decomposition (Sax and Lewis, 1987).
Metabolic pathwayThe metabolic transformations of profenofos in plants and animals are similar and occur via hydrolysis to 4-bromo-2-chlorophenol which is then conjugated.
MetabolismProfenofos orally administered to rats is rapidly excreted, mainly in the urine. The principal degradation route is hydrolysis to 4-bromo-2-chlorophenol followed by conjugation. DT50 in soil is about 1 week.
Toxicity evaluationThe acute oral LD50 for rats is 358 mg/kg. Inhalation LC50 (4 h) for rats is about 3 mg/L air. NOEL (2 yr) for rats is 0.3 mg/kg diet (0.015 mg/kg/d). ADI is 0.01 mg/kg b.w.
DegradationProfenofos is stable under neutral and slightly acid conditions but it is hydrolysed in alkaline solution. The DT50 values at pH 5, 7 and 9 (20°C) were 93 days, 14.6 days and 5.7 hours, respectively (PM).
Tag:Profenofos(41198-08-7) Related Product Information
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