- 4-Hydroxybenzophenone
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- $99.00/ kg
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2026-04-30
- CAS:1137-42-4
- Min. Order: 0.0010000000474974513kg
- Purity: 99%
- Supply Ability: 5000
- 4-Hydroxybenzophenone
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- $0.00 / 1removed
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2026-04-22
- CAS:1137-42-4
- Min. Order:
- Purity: 99.84%
- Supply Ability: 10g
- 4-Hydroxybenzophenone
-
- $0.00 / 1removed
-
2026-04-22
- CAS:1137-42-4
- Min. Order:
- Purity: 99.84%
- Supply Ability: 10g
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| | 4-Hydroxybenzophenone Basic information |
| | 4-Hydroxybenzophenone Chemical Properties |
| Melting point | 132-135 °C(lit.) | | Boiling point | 260-262°C 42mm | | density | 1.1184 (rough estimate) | | vapor pressure | 0Pa at 20℃ | | refractive index | 1.5954 (estimate) | | Fp | 260-262°C/24mm | | storage temp. | Store below +30°C. | | solubility | Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) | | pka | 8.14±0.13(Predicted) | | form | Powder | | color | White to beige to brown | | Water Solubility | Insoluble in water. | | BRN | 777776 | | InChI | 1S/C13H10O2/c14-12-8-6-11(7-9-12)13(15)10-4-2-1-3-5-10/h1-9,14H | | InChIKey | NPFYZDNDJHZQKY-UHFFFAOYSA-N | | SMILES | Oc1ccc(cc1)C(=O)c2ccccc2 | | LogP | 1.6 at 35℃ | | CAS DataBase Reference | 1137-42-4(CAS DataBase Reference) | | NIST Chemistry Reference | Methanone, (4-hydroxyphenyl)phenyl-(1137-42-4) | | EPA Substance Registry System | Methanone, (4-hydroxyphenyl)phenyl- (1137-42-4) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36/37-24/25-36 | | WGK Germany | 2 | | RTECS | PC4959775 | | Hazard Note | Irritant | | TSCA | TSCA listed | | HS Code | 29145000 | | Storage Class | 11 - Combustible Solids | | Hazard Classifications | Aquatic Chronic 3
STOT RE 2 |
| | 4-Hydroxybenzophenone Usage And Synthesis |
| Chemical Properties | white to beige fine crystalline powder | | Uses | 4-Hydroxybenzophenone is used in the field of organic synthesis. It is used as pharmaceutical intermediate of clomifene citrate. | | Uses | Metabolite of benzophenone. | | Preparation | Preparation by condensation of benzotrichloride,
with phenol in the presence of aluminium chloride in carbon disulfide at 0° (90%) or in the presence of zinc oxide in a water bath;
with p-bromophenol in 30% sodium hydroxide solution at 80–85° (81%). There is substitution of the bromine atom by the benzoyl group. | | Definition | ChEBI: 4-Hydroxybenzophenone is a member of benzophenones. | | Synthesis Reference(s) | Journal of the American Chemical Society, 77, p. 4674, 1955 DOI: 10.1021/ja01622a074
The Journal of Organic Chemistry, 19, p. 978, 1954 DOI: 10.1021/jo01371a016
Tetrahedron Letters, 31, p. 3943, 1990 DOI: 10.1016/S0040-4039(00)97513-0 | | Flammability and Explosibility | Not classified | | Purification Methods | Dissolve p-benzoylphenol in hot EtOH (charcoal), filter and cool. Alternatively crystallise it once from EtOH/H2O and twice from *benzene [Grunwald J Am Chem Soc 73 4934 1951, Dryland & Sheppard J Chem Soc Perkin Trans 1 125 1986]. [Beilstein 8 IV 1263.] |
| | 4-Hydroxybenzophenone Preparation Products And Raw materials |
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