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ChemicalBook >> CAS DataBase List >> Dexrazoxane

Dexrazoxane

Dexrazoxane price.
  • $5 - $1224
  • Product name: Dexrazoxane
  • CAS: 24584-09-6
  • MF: C11H16N4O4
  • MW: 268.27
  • EINECS:206-169-7
  • MDL Number:MFCD00866449
  • Synonyms:DEXRAZOXANE;(s)-4,4'-(1-methyl-1,2-ethanediyl)bis-2,6-piperazinedione;4’-(1-methyl-1,2-ethanediyl)bis-6-piperazinedion(+)-4 ;4’-propylenedi-6-piperazinedion(+)-4 ;adr529 ;cardioxane ;DEXTRORAZOXANE;(S)-ICRF-187
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  • aablocks
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Package
  • 10mM*1mLinDMSO(Solid+Solvent)
  • 10mg
  • 10mM*1mLinDMSO(Solution)
  • 1mg
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  • Manufactureraablocks
  • Product numberAA002OL7
  • Product descriptionDexrazoxane 98%(HPLC)
  • Packaging1mg
  • Price$9
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA002OL7
  • Product descriptionDexrazoxane ≥97%
  • Packaging5mg
  • Price$10
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA002OL7
  • Product descriptionDexrazoxane ≥97%
  • Packaging25mg
  • Price$12
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA002OL7
  • Product descriptionDexrazoxane 98%(HPLC)
  • Packaging50mg
  • Price$20
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA002OL7
  • Product descriptionDexrazoxane 98%(HPLC)
  • Packaging100mg
  • Price$24
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA002OL7
  • Product descriptionDexrazoxane 98%(HPLC)
  • Packaging250mg
  • Price$29
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA002OL7
  • Product descriptionDexrazoxane 98%(HPLC)
  • Packaging1g
  • Price$68
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA002OL7
  • Product descriptionDexrazoxane ≥97%
  • Packaging5g
  • Price$319
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA002OL7
  • Product descriptionDexrazoxane 98%
  • Packaging25g
  • Price$974
  • Updated2026-05-28
  • Buy
  • ManufacturerAK Scientific
  • Product numberE488
  • Product descriptionDexrazoxane 98%
  • Packaging25g
  • Price$1165
  • Updated2026-06-04
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  • ManufacturerAK Scientific
  • Product numberJ90038
  • Product descriptionDexrazoxane
  • Packaging5g
  • Price$600
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberE488
  • Product descriptionDexrazoxane 98%
  • Packaging5g
  • Price$388
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ90038
  • Product descriptionDexrazoxane 95%
  • Packaging5g
  • Price$290
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ90038
  • Product descriptionDexrazoxane 95%
  • Packaging25g
  • Price$870
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ90038
  • Product descriptionDexrazoxane 95%
  • Packaging1g
  • Price$86
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberE488
  • Product descriptionDexrazoxane 98%
  • Packaging1g
  • Price$114
  • Updated2026-06-04
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA002OL7 Dexrazoxane 98%(HPLC) 1mg $9 2026-05-28 Buy
aablocks AA002OL7 Dexrazoxane ≥97% 5mg $10 2026-05-28 Buy
aablocks AA002OL7 Dexrazoxane ≥97% 25mg $12 2026-05-28 Buy
aablocks AA002OL7 Dexrazoxane 98%(HPLC) 50mg $20 2026-05-28 Buy
aablocks AA002OL7 Dexrazoxane 98%(HPLC) 100mg $24 2026-05-28 Buy
aablocks AA002OL7 Dexrazoxane 98%(HPLC) 250mg $29 2026-05-28 Buy
aablocks AA002OL7 Dexrazoxane 98%(HPLC) 1g $68 2026-05-28 Buy
aablocks AA002OL7 Dexrazoxane ≥97% 5g $319 2026-05-28 Buy
aablocks AA002OL7 Dexrazoxane 98% 25g $974 2026-05-28 Buy
AK Scientific E488 Dexrazoxane 98% 25g $1165 2026-06-04 Buy
AK Scientific J90038 Dexrazoxane 5g $600 2021-12-16 Buy
AK Scientific E488 Dexrazoxane 98% 5g $388 2026-06-04 Buy
AK Scientific J90038 Dexrazoxane 95% 5g $290 2026-06-04 Buy
AK Scientific J90038 Dexrazoxane 95% 25g $870 2026-06-04 Buy
AK Scientific J90038 Dexrazoxane 95% 1g $86 2026-06-04 Buy
AK Scientific E488 Dexrazoxane 98% 1g $114 2026-06-04 Buy

Properties

Melting point :194-196°C
alpha :D +11.35° (c = 5 in DMF)
Boiling point :531.5±50.0 °C(Predicted)
Density :1.333±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: >20mg/mL
form :powder
pka :2.1(at 25℃)
color :white to off-white
Merck :14,8123
Henry's Law Constant :4.7×1013 mol/(m3Pa) at 25℃, HSDB (2015)
Major Application :clinical testing
InChI :InChI=1S/C11H16N4O4/c1-7(15-5-10(18)13-11(19)6-15)2-14-3-8(16)12-9(17)4-14/h7H,2-6H2,1H3,(H,12,16,17)(H,13,18,19)/t7-/m0/s1
InChIKey :BMKDZUISNHGIBY-ZETCQYMHSA-N
SMILES :[C@H](N1CC(=O)NC(=O)C1)(C)CN1CC(=O)NC(=O)C1
CAS DataBase Reference :24584-09-6(CAS DataBase Reference)

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Dexrazoxane is an intracellular iron chelator and an inhibitor of topoisomerase IIα. Through these activities, dexazoxane is highly protective in reducing anthracycline-induced cardiotoxicity and extravasation injury. Dexrazoxane has also been shown to act as an antioxidant that scavenges hydroxyl (IC50 = 2.1 mM), superoxide (IC50 = 0.4 mM), lipid (IC50 = 4.4 mM), 2,2-diphenyl-1-picrylhydrazyl (IC50 = 3.5 μM), and 2,2’-azino-bis(3-ethylbenzthiazoline-6-sulphonic acid) (IC50 = 3.8 mM) free radicals.

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