2-ethylquinazolin-4-ol synthesis
- Product Name:2-ethylquinazolin-4-ol
- CAS Number:3137-64-2
- Molecular formula:C10H10N2O
- Molecular Weight:174.2
78-39-7
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$9.00/1g
134-20-3
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$13.00/25mL
3137-64-2
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$45.00/50mg
Yield: 72%
Reaction Conditions:
with ammonium acetate for 30 h;Reflux;
Steps:
2 preparation of 2-ethyl-quinazoline -4 (3H)-one (IX)
In the reaction flask by adding 2-aminobenzoic acid methyl ester (6.04g, 40mmol), ammonium acetate (7.70g, 100mmol) and orthopropionate three b ester (25 ml), heating to reflux 30h. Cooling to room temperature, solid of the absorptions, dry, recrystallized with ethanol, the white solid obtained 5.01g, yield 72%,
References:
Capital Normal University;Cao, shengli;Xu, Xingzhi;liao, Ji;Han, Xue;Yuan, xiaoli;Wang, Fucheng;Hu, xiaojie CN105503745, 2016, A Location in patent:Paragraph 0197; 0198
