3-BENZYLOXYBROMOBENZENE synthesis
- Product Name:3-BENZYLOXYBROMOBENZENE
- CAS Number:53087-13-1
- Molecular formula:C13H11BrO
- Molecular Weight:263.13
591-20-8
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100-39-0
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53087-13-1
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Yield:53087-13-1 100%
Reaction Conditions:
with potassium carbonate in acetone; for 15 h;Reflux;
Steps:
79.79-1 Preparation of 1-(benzyloxy)-3-bromobenzene
A solution of 3-bromophenol (3 g, 17.34 mmol) in acetone (100 mL) was added with benzyl bromide (2.2 mL, 19.07 mmol) and K2CO3 (7.0 g, 52.02 mmol), and the resulting mixture was refluxed for 15 hours. The reaction mixture was cooled to room temperature, filtered, and washed with acetone. The filtrate was concentrated and purified by silica gel chromatography to obtain the title compound (white solid, 5.1 g, 100% yield). 1H NMR (300 MHz, CDCl3) δ 7.50 - 7.30 (m, 5H), 7.20 - 7.01 (m, 3H), 6.98 - 6.80 (m, 1H), 5.05 (s, 2H).
References:
EP2963027,2016,A1 Location in patent:Paragraph 1227; 1228; 1229
591-20-8
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100-44-7
659 suppliers
$13.50/250G
53087-13-1
218 suppliers
$11.00/5g
89598-96-9
350 suppliers
$9.00/1g
100-39-0
437 suppliers
$10.00/10g
53087-13-1
218 suppliers
$11.00/5g
585-79-5
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100-51-6
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$5.00/100g
53087-13-1
218 suppliers
$11.00/5g
591-20-8
358 suppliers
$10.00/1g
584-08-7
1228 suppliers
$5.00/100g
100-44-7
659 suppliers
$13.50/250G
53087-13-1
218 suppliers
$11.00/5g