Methyl 6-bromopicolinate synthesis
- Product Name:Methyl 6-bromopicolinate
- CAS Number:26218-75-7
- Molecular formula:C7H6BrNO2
- Molecular Weight:216.03
21190-87-4
396 suppliers
$10.00/5g
26218-75-7
240 suppliers
$9.00/1g
Yield:26218-75-7 90%
Reaction Conditions:
with methanol;sulfuric acidHeating / reflux;
Steps:
19
To a solution of 6-bromopicolinic acid (2.5 g) in MeOH (100 mL) was added concentrated H2SO4 (5 mL). The reaction was refluxed until the 6-bromopicolinic acid was gone. The mixture was dried by evaporation and then purified by silica gel column chromatography (ISCO) to give compound 19A (ca 90% yield). LC/MS: m/z 216/218 (M+H+).
References:
Li, James J,;Hamann, Lawrence G.;Ruan, Zheming;Cooper, Christopher B.;Wu, Shung C.;Simpkins, Ligaya M.;Wang, Haixia;Nayeem, Akbar;Krystek, Stanley R. US2006/235028, 2006, A1 Location in patent:Page/Page column 32
67-56-1
776 suppliers
$7.29/5ml-f
21190-87-4
396 suppliers
$10.00/5g
26218-75-7
240 suppliers
$9.00/1g
21190-87-4
396 suppliers
$10.00/5g
74-88-4
354 suppliers
$15.00/10g
26218-75-7
240 suppliers
$9.00/1g
67-56-1
776 suppliers
$7.29/5ml-f
34160-40-2
350 suppliers
$6.00/1g
26218-75-7
240 suppliers
$9.00/1g
626-05-1
512 suppliers
$9.00/10g
26218-75-7
240 suppliers
$9.00/1g