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ChemicalBook CAS DataBase List Aprepitant
502537-07-7

Aprepitant synthesis

3synthesis methods
407-25-0 Synthesis
Trifluoroacetic anhydride

407-25-0
468 suppliers
$9.00/1g

287930-73-8 Synthesis
4-BENZYL-2-HYDROXY-MORPHOLIN-3-ONE

287930-73-8
227 suppliers
$6.00/5g

Aprepitant

502537-07-7
10 suppliers
inquiry

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Yield:-

Reaction Conditions:

in acetonitrile at 5 - 34;

References:

Brands, Karel M. J.;Payack, Joseph F.;Rosen, Jonathan D.;Nelson, Todd D.;Candelario, Alexander;Huffman, Mark A.;Zhao, Matthew M.;Li, Jing;Craig, Bridgette;Song, Zhiguo J.;Tschaen, David M.;Hansen, Karl;Devine, Paul N.;Pye, Philip J.;Rossen, Kai;Dormer, Peter G.;Reamer, Robert A.;Welch, Christopher J.;Mathre, David J.;Tsou, Nancy N.;McNamara, James M.;Reider, Paul J. [Journal of the American Chemical Society,2003,vol. 125,# 8,p. 2129 - 2135]

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