Betulonicacid synthesis
- Product Name:Betulonicacid
- CAS Number:4481-62-3
- Molecular formula:C30H46O3
- Molecular Weight:454.68
472-15-1
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$5.00/25mg
4481-62-3
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$25.00/5mg
Yield:4481-62-3 93%
Reaction Conditions:
with Jones reagent in dichloromethane;acetone at 20; for 0.25 h;Cooling;
Steps:
3.2.11 Betulonic acid (7)
Jones’ reagent: CrO3 (26.72 g) was dissolvedin H2SO4 (23 ml); then, the solutionwas diluted to 100 ml with water. Asolution of BA (500 mg, 1.09mmol) inCH2Cl2 (12 ml) and acetone (12 ml) wascooled, to which Jones’ reagent (1 ml) wasslowly added. The mixture was stirred atroom temperature for 15 min; then, MeOH(5 ml) was added. After another stirring for10 min, CH2Cl2 (20 ml) was added and theorganic layer was washed with water andsaturated NaCl solution sequentially, driedover anhydrous Na2SO4, and concentratedin vacuo. The product was recrystallized inMeOH for three times as a white solid(462 mg, 93%).
References:
Liu, Jin-Hong;Tang, Jia;Zhu, Zi-Fei;Chen, Li [Journal of Asian Natural Products Research,2014,vol. 16,# 1,p. 34 - 42]
473-98-3
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$16.35/10mg
4481-62-3
213 suppliers
$25.00/5mg
4439-98-9
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inquiry
4481-62-3
213 suppliers
$25.00/5mg
473-98-3
421 suppliers
$16.35/10mg
4439-98-9
11 suppliers
inquiry
4481-62-3
213 suppliers
$25.00/5mg
7020-34-0
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4481-62-3
213 suppliers
$25.00/5mg