ChemicalBook CAS DataBase List Calcium Propionate

Calcium Propionate synthesis

6synthesis methods

Product Name:Calcium Propionate
CAS Number:4075-81-4
Molecular formula:C3H8CaO2
Molecular Weight:116.17

The industrial production of Calcium propionate and sodium propionate is carried out by the neutralization of propionic acid with the corresponding hydroxides and subsequent spraydrying of the concentrated aqueous solutions.

554-12-1 Synthesis

554-12-1
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$21.00/25mL

4075-81-4
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$14.00/25g

Yield:4075-81-4 95.9%

Reaction Conditions:

with water monomer;calcium(II) oxide at 60; for 2.75 h;Temperature;

Steps:

2; 5 Conversion of Methyl Propionate to Calcium Propionate

To a three-necked round bottom flask placed in a heating mantle and equipped with a mechanical stirrer, temperature-measuring thermocouple, and pressure-equalizing dropping funnel, was charged 1600 g of city water followed by 127.7 g (2.28 mole) of lime (95%; Specialty Minerals, Inc) added in 6 min. To this stirred slurry was dropwise added 399 g (4.53 mole) of methyl propionate (99.95%; Lucite) over a period of 0.75 hr. After this addition was complete, the resultant reaction solution was kept at 60° for 2 hr and had a pH of 12.2. The pH was adjusted to 7.2 by addition of 38.8 g of propionic acid. The temperature of the reaction solution was raised to 95° C. to distill volatile components into a receiver. A total of 575.9 g of distillate was collected over a period of 6 hr. Analysis of this distillate gave 426.4 g of water by Karl Fischer titration. The volatile organic constituents of the distillate were analyzed by gas chromatography to give 149.5 g of methanol (103% recovery). The removal of the water by distillation was calculated to ensure that the remaining contents of the round bottom flask was a 26% aqueous solution of calcium propionate. This solution was filtered through diatomaceous earth. Upon cooling, solids were precipitated, removed by filtration, and dried in an oven to give 404.3 g of calcium propionate (95.9% yield) as a white solid. Analysis by standard Ca-EDTA titration gave a purity of 99.8%.

References:

US2022/81384,2022,A1 Location in patent:Paragraph 0042; 0045