ChemicalBook CAS DataBase List Dimethyl Glutarate

Dimethyl Glutarate synthesis

9synthesis methods

Product Name:Dimethyl Glutarate
CAS Number:1119-40-0
Molecular formula:C7H12O4
Molecular Weight:160.17

67-56-1 Synthesis

67-56-1
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108-55-4 Synthesis

108-55-4
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$6.00/25g

1119-40-0
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$5.00/10g

Yield:1119-40-0 96%

Reaction Conditions:

with sulfuric acid at 20; for 18 h;

Steps:

Dimethyl glutarate (1l)⁷
Glutaric anhydride (29.4 mmol, 3.35 g) was dissolved in anhydrous MeOH (100 mL) and conc. H₂SO₄ (5.9 mmol, 0.31 mL) was added. After being stirred at room temperature for 18 h, the mixture was concentrated to a half volume and quenched with water (40 mL) afterwards. The aqueous phase was extracted with CH₂Cl₂ (3 x 50 mL), the combined organic phases were washed with brine (30 mL), dried over Na₂SO₄ and concentrated to give dimethyl glutarate 1l (4.53 g, 96%) as a colourless clear oil; ¹H NMR (CDCl₃): δ =1.96 (quint, J = 7.2 Hz, 2H), 2.39 (t, J = 7.2 Hz, 4H).

References:

Sivák, Ivan;Václav, Jakub;Berkeš, Dušan;Kolarovič, Andrej [Tetrahedron,2015,vol. 71,# 47,p. 8871 - 8875] Location in patent:supporting information

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67-56-1 Synthesis

67-56-1
727 suppliers
$7.29/5ml-f

110-94-1 Synthesis