ChemicalBook CAS DataBase List Propamidine

Propamidine synthesis

8synthesis methods

Product Name:Propamidine
CAS Number:104-32-5
Molecular formula:C17H20N4O2
Molecular Weight:312.37

Commercial production of propamidine follows the classic industrial route for generating aromatic diamidines from dinitrile precursors. Manufacturers begin with a bis substituted aromatic dinitrile, which is converted to the corresponding imidate ester under acidic alcoholysis. This activated intermediate is then reacted with propylamine, producing the bis amidine framework through sequential nucleophilic substitution. The process requires careful control of moisture and temperature to prevent hydrolysis and to ensure full conversion of both nitrile groups. After neutralisation and purification, the technical material is isolated as a stable salt suitable for downstream formulation.

100-02-7 Synthesis

100-02-7
99 suppliers
$11.00/5G

104-32-5
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Yield:-

Steps:

Multi-step reaction with 4 steps
1: ethanolic NaOH
2: aqueous sodium sulfide
3: ueber die Diazonium-Verbindung dargestellt
4: 180 - 195 °C

References:

Partridge;Short [Journal of the Chemical Society,1947,p. 390,391]

4,4'-(1,3-Propanediylbisoxy)bisbenzonitrile

7476-06-4
6 suppliers
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104-32-5
27 suppliers
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References

767-00-0 Synthesis

767-00-0
547 suppliers
$6.00/25g

104-32-5
27 suppliers
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References

7476-06-4
6 suppliers
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19402-64-3
75 suppliers
$8.00/250mg

104-32-5
27 suppliers
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References

Ethanamine, N-[(3,5-dichlorophenyl)methylene]-2,2-diethoxy-

1000210-73-0
0 suppliers
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104-32-5
27 suppliers
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References

Propamidine Related Search:

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