Proxan sodium synthesis
- Product Name:Proxan sodium
- CAS Number:140-93-2
- Molecular formula:C4H7NaOS2
- Molecular Weight:158.22
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Yield:140-93-2 136.67 g
Reaction Conditions:
Stage #1:isopropyl alcohol with sodium at 65; for 3 h;Inert atmosphere;
Stage #2:carbon disulfide for 1 h;
Steps:
Sodium isopropyl xanthate
In a flask equipped with a mechanical stirrer, isopropanol (871.10 grams, 14.49 moles) was bubbled with nitrogen. Sodium metal cubes (20.25 grams, 0.88 moles, Sigma-Aldrich Corporation, Milwaukee, WI) were cut into small pieces and added to the flask over 3 hours. The temperature was then increased to 65 °C. The sodium dissolved with evolution of hydrogen over 3 additional hours resulting in a clear solution. The mixture was cooled to 35°C using an ice bath, which resulted in a thick slurry. Carbon disulfide (73.80 grams, 0.97 moles) was then added slowly over 30 minutes. After full addition, the mixture was stirred for an additional 30 minutes resulting in a yellow solution. Solvent was removed by placing the mixture under vacuum resulting in a yellow solid. The product was further dried under high vacuum (1 millimeter Hg) for 4 hours resulting in a yellow powder (136.67 grams).
References:
3M INNOVATIVE PROPERTIES COMPANY;LEWANDOWSKI, Kevin M.;ROSCOE, Stephen B.;GADDAM, Babu N.;WHITING, Bryan T.;BATTISTE, John L. WO2019/162806, 2019, A1 Location in patent:Page/Page column 49
