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2-Iodoaniline

CAS No.
615-43-0
Chemical Name:
2-Iodoaniline
Synonyms
O-IODOANILINE;2-lodoaniline;Aniline o-iodine;2-IodoaniL;2-Iodylamine;2-IODOANILINE;Aniline, 2-iodo-;Aniline, o-iodo-;2-Iodoaniline>2-iodo-benzenamin
CBNumber:
CB5125267
Molecular Formula:
C6H6IN
Molecular Weight:
219.02
MDL Number:
MFCD00007680
MOL File:
615-43-0.mol
MSDS File:
SDS
Last updated:2024-04-26 14:09:12

2-Iodoaniline Properties

Melting point 55-58 °C (lit.)
Boiling point 262.0±23.0 °C(Predicted)
Density 1.8155 (estimate)
Flash point >230 °F
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility soluble in Chloroform, DCM, Ethyl Acetate, Toluene
form Crystalline Needles
pka 2.6(at 25℃)
color Yellow to brown
Water Solubility Insoluble in water.
Sensitive Light Sensitive
BRN 2204899
InChIKey UBPDKIDWEADHPP-UHFFFAOYSA-N
CAS DataBase Reference 615-43-0(CAS DataBase Reference)
NIST Chemistry Reference Benzenamine, 2-iodo-(615-43-0)
EPA Substance Registry System o-Iodoaniline (615-43-0)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
Hazard Codes  Xn,Xi
Risk Statements  20/21/22-37/38-36/37/38
Safety Statements  36/37-36/37/39-26-36
RIDADR  2811
WGK Germany  3
8
Hazard Note  Irritant
TSCA  T
HazardClass  6.1(b)
PackingGroup  III
HS Code  29214210
NFPA 704
0
2 0

2-Iodoaniline price More Price(47)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich I7004 2-Iodoaniline 98% 615-43-0 5g $50.2 2024-03-01 Buy
Sigma-Aldrich I7004 2-Iodoaniline 98% 615-43-0 25g $123 2024-03-01 Buy
TCI Chemical I0046 2-Iodoaniline 615-43-0 5G $36 2024-03-01 Buy
TCI Chemical I0046 2-Iodoaniline 615-43-0 25G $101 2024-03-01 Buy
Alfa Aesar A13059 2-Iodoaniline, 98+% 615-43-0 5g $37.65 2024-03-01 Buy
Product number Packaging Price Buy
I7004 5g $50.2 Buy
I7004 25g $123 Buy
I0046 5G $36 Buy
I0046 25G $101 Buy
A13059 5g $37.65 Buy

2-Iodoaniline Chemical Properties,Uses,Production

Chemical Properties

YELLOW TO BROWN CRYSTALLINE NEEDLES

Uses

2-Iodoaniline is used as an intermediate in organic synthesis.

Uses

2-Iodobenzenamine is an synthetic intermediate for the synthesis of complex organic compounds and pharmaceuticals.

Preparation

2-iodoaniline and its derivatives are commonly used for the preparation of indole-based anticancer drugs, which have high market value, and further synthesis can lead to high-end synthetic intermediates with complex structures.
Take a reaction tube, add 50mg of sodium azide, 75mg of 1-(2-iodophenyl)ethanol, 300uL of trifluoroacetic acid, 150uL of methanesulfonic acid and 1.0mL of hexane, and stir for 24 hours at 40℃. After the reaction, 10 mL of sodium hydroxide solution was added to quench the reaction. The organic phase was washed with 5 mL of brine, and the organic phase was combined and separated by column chromatography to obtain 58.4 mg of 2-iodoaniline in 89% yield.
Synthesis of 2-iodoaniline
Synthesis of 2-iodoaniline

Purification Methods

Distil 2-iodoaniline with steam and crystallise it from *benzene/pet ether. The N-acetyl derivative has m 110o. [Beilstein 12 IV 1542.]

Global( 494)Suppliers
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Dalian Richfortune Chemicals Co., Ltd
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View Lastest Price from 2-Iodoaniline manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-Iodoaniline pictures 2024-04-27 2-Iodoaniline
615-43-0
US $5.00 / kg 1kg 99.92% 50000tons Ouhuang Engineering Materials (Hubei) Co., Ltd
2-Iodoaniline pictures 2023-12-24 2-Iodoaniline
615-43-0
US $100.00-1.00 / KG 1KG 99% g-kg-tons, free sample is available Henan Fengda Chemical Co., Ltd
2-Iodoaniline pictures 2023-08-29 2-Iodoaniline
615-43-0
US $10.00 / kg 100kg 99% 10000kgs Dalian Richfortune Chemicals Co., Ltd
  • 2-Iodoaniline pictures
  • 2-Iodoaniline
    615-43-0
  • US $5.00 / kg
  • 99.92%
  • Ouhuang Engineering Materials (Hubei) Co., Ltd
  • 2-Iodoaniline pictures
  • 2-Iodoaniline
    615-43-0
  • US $100.00-1.00 / KG
  • 99%
  • Henan Fengda Chemical Co., Ltd
  • 2-Iodoaniline pictures
  • 2-Iodoaniline
    615-43-0
  • US $10.00 / kg
  • 99%
  • Dalian Richfortune Chemicals Co., Ltd
LABOTEST-BB LTBB000671 BENZENAMINE, 2-IODO- 2-Iodoaniline o-Iodoaniline 2-IODOANILINE 98% 2-Iodoaniline, 98+% 1-Amino-2-iodobenzene 2-Iodoaniline, 98% 25GR 2-Iodoaniline, 98% 5GR 2-iodo-benzenamine 2-Iodoaniline, 97+% Aniline adjacent iodine 2-iodo-benzenamin 2-Iodo-phenylamine Aniline, 2-iodo- Aniline, o-iodo- o-Aminoiodobenzene OTAVA-BB BB7020410063 2-IODOANILINE 2-IodoaniL 2-Iodoaniline, 98%, for synthesis 2-Iodoaniline> 2-Iodoaniline ISO 9001:2015 REACH 2-lodoaniline Aniline o-iodine O-IODOANILINE 2-Iodylamine 2-(Dimethylphosphinyl)benzeneamine (2-Iodoaniline) 615-43-0 C6H6NI C6H6IN AMINE C2 to C6 Building Blocks Amines Organic Building Blocks Nitrogen Compounds Anilines, Aromatic Amines and Nitro Compounds Amines Phenyls & Phenyl-Het Anilines, Amides & Amines Iodine Compounds Phenyls & Phenyl-Het C2 to C6 Nitrogen Compounds Pharmaceutical Intermediates bc0001